The aim of this retrospective study is to investigate the prevalence, three-dimensional positions and supplementary findings of the presence of a mesiodens by using cone-beam computed tomography. A total of 5000 cone-beam computed tomography (CBCT) scans, taken between December 2015 and March 2018, from the archive of Istanbul University Faculty of Dentistry Department of Oral and Maxillofacial Radiology, were screened. In sum, 2003 CBCT scans fulfilled inclusion criteria in this study. In addition to number of mesiodens, age and sex of the patients, shape, eruption status and direction, findings of the presence of a mesiodens were also recorded. Mesiodentes were classified according to their positions in frontal, sagittal and axial planes. In this study, the prevalence of mesiodens was found 5.04% and to be more frequent in males than in females with the ratio of 1.9 : 1. One hundred thirty maxillary mesiodentes were detected in 101 cases out of 2003 CBCT scans. In 77 cases (76.2%), single mesiodens; in 19 cases (18.8%), two mesiodentes; and in 5 cases (4.9%), three mesiodentes were found. According to our classification, mesiodentes were mostly found in between midlines of central incisors (both the crown and root of mesiodens) in frontal plane, impacted and in contact with central incisors in sagittal plane, anterior to nasopalatine canal and in contact with nasopalatine canal in axial plane. Cone-beam computed tomography provides more detailed information about position, neighbouring anatomic structures, and local findings of the presence of mesiodentes in multiplanar sections.

Amaç: Bu çalışmanın amacı Türk toplumunda dental anomali görülme sıklığının cinsiyet ve yaşa göre araştırılmasıdır.Gereç ve Yöntem: Çalışmada İstanbul Üniversitesi Diş Hekimliği Fakültesi Ağız, Diş-Çene Radyolojisi Anabilim Dalı’na başvuran, yaşları 9-35 yaş arasında değişen (ortalama yaş: 25.61±10.04) 2025 hastanın (885 erkek ve 1140 kadın) panoramik radyografileri geriye dönük olarak araştırılmıştır. Hastalar hipodonti, hiperdonti, mikrodonti, taurodontizm ve diğer kök anomalileri gibi dental anomalilerin varlığı açısından incelenmiştir. Bu anomalilerin görülme oranları cinsiyet ve yaşa göre değerlendirilmiştir.Bulgular: 2025 hastanın toplam 96’sının (42 erkek, 54 kadın) incelenen dental anomalilerden en az birine sahip olduğu belirlenmiştir (%4.74). en sık gözlenen dental anomali diş eksikliği olup (%1.77) bunu sırasıyla taurodontizm (%1.18), hiperdonti (%0.79), mikrodonti (%0.54) ve diğer kök anomalileri (%0.44) takip etmektedir.Sonuç: Diş eksikliği incelenen populasyonda en sık gözlenen gelişimsel dental anomali olup bunu taurodontizm takip etmektedir

In this study, we compared the bone-healing effects of the local application of platelet-rich fibrin (PRF) and hyaluronic acid (HA) to bilateral tibial fractures in rats. Twenty-three adult male Sprague-Dawley rats were used. Twenty-two animals were randomly allocated to a control group (n = 6) and 2 study groups: PRF (n = 8) and HA (n = 8). The 23rd rat was used as a donor to obtain PRF. Each group was divided into 2 subgroups for histomorphometric and radiologic assessments at 2 and 6 weeks. Foreign body reaction, necrosis, inflammation, new bone formation, and fibrosis were investigated as bone healing parameters in terms of histopathologic analysis. The difference between the groups for these parameters was evaluated. The radiologic evaluation was performed by comparing the 3-dimensional reconstruction images of the fracture sites between the study and control groups. Histomorphometric evaluation showed that at 2 weeks postoperatively, the control group showed lesser bone formation (26.1 ± 6.6%) when compared to the study (HA: 54.7 ± 9.7%; PRF: 75.3 ± 19.2%) groups and PRF group showed highest total ossification. At 6 weeks postoperatively the PRF group showed lesser total ossification (50.7 ± 28.2%) when compared to control (76.3 ± 21.7%) and HA group. The HA (88.8 ± 13.3%) showed highest total ossification. In the control group, fibrosis was more prominent at week 6, whereas in the HA and PRF groups the amount of ossification increased. In contrast to histopathologic healing, radiologic bone healing did not differ significantly among the study and control groups 2 weeks after surgery, whereas at 6 weeks, the results of radiologic bone formation were in accordance with those of histopathologic bone healing.

Kose TE, et al. J Adv Prosthodont. 2015 Oct;7(5):380-385. http://dx.doi.org/10.4047/jap.2015.7.5.380