Objective: Delta neutrophil index is a parameter that shows the ratio of immature granulocytes to the neutrophil count. This study aims to determine the power of DNI in predicting the presence of strangulation in incarcerated inguinal hernias. Methods: The files of the patients who were admitted to our clinic and operated due to incarcerated inguinal hernia between May 2021 and May 2022 were reviewed retrospectively. The patients' age, gender, hernia type, leukocyte, lymphocyte, neutrophil, platelet, monocyte values, delta neuthrophil index, the surgical method applied, and whether bowel resection was performed were extracted from the patient files. The patients were divided into two groups patients who underwent bowel resection because of bowel ischemia (group 1) and those who did not (group 2). Results: Eighty-one patients were included in the study. It was determined that 70 (86.4%) patients did not undergo bowel resection, and 11 (13.6%) underwent bowel resection. The median DNI value of the patients in Group 1 was 0.30 (0.10 - 1.20), and the median DNI value of the patients in Group 2 was 0.30 (0.10 - 1.30), and the difference was not statistically significant (p=0.77) Conclusion: Delta neutrophil index may not be an accurate predictive value to predict the presence of ischemia in the incarcerated bowel segment in patients with incarcerated inguinal hernia.
30 August 2022 in JOURNAL OF BIOTECHNOLOGY AND STRATEGIC HEALTH RESEARCH
Background: Thyroid nodules are mostly benign. Although it varies by region, 5.4% of nodules in men and 6.5% of nodules in women may be malignant. In rural regions where a radiologist, an endocrine surgeon, a cytologist, and an endocrinologist are not present, difficulties may be experienced in the management of thyroid nodules. Objectives: This present study aims to determine if it is possible to comment on whether the nodule is malignant by evaluating the biological markers in patients with thyroid nodules. Methods: We reviewed retrospectively the data of patients between January 2019 and September 2020 who underwent total thyroidectomy in terms of thyroid ultrasonography results, thyroid fine-needle aspiration biopsy results, neutrophil, platelet, lymphocyte, red blood cell, and mean erythrocyte volume (MCV) values, histopathological examination results of thyroid specimens. Subsequently, we calculated Mentzer index, Systemic immune-inflammatory index, and neutrophil-lymphocyte ratio for each patient. Results: 140 patients were included in the study. 110 (78.6%) of the patients were female and 30 (21.4%) were male. The mean age of the patients was 48 ± 12.5 (20-76). There was no statistically significant difference in Mentzer index, Systemic inflammatory index, and neutrophil-lymphocyte ratios between patients with malignant and benign thyroid nodules. Conclusion: Biological markers have limited predictive power in the management of thyroid nodules. Therefore, the use of biomarkers that we have studied in the treatment of thyroid nodules does not seem possible at present.
Amaç : Günümüzde yapılan bazı tiroid biyopsi sonuçlarında takip mi yoksa tedavi mi konusu halen tartışmalıdır. Hangi özelliklere sahip Tiroid nodüllerinde ameliyat veya takip yapılmasında birden fazla biyopsi yapılmasının tedavideki yerini araştırmayı amaçladık Yöntem : Bir üçüncü basamak hastanede 2014-2022 yılları arasında Tiroidektomi yapılan olgular retrospektif incelendi. Preoperatif biyopsi ve postoperatif patoloji sonuçları bağımsız değişkenlerle karşılaştırıldı. Bulgular : Radyolojik TI-RADS sınıflaması yüksek, artmış nodül çapı olan ve ilaçla regüle olan grupta artmış malignite riski görüldü (p < 0.05). Önemi belirsiz atipi grubunda artmış TI-RADS postoperatif malign patolojiyle uyumlu bulundu. Sonuç : İlk biyopsi sonucu cerrahi açıdan şüpheli olgularda TI-RADS sınıflaması ve nodül çapı tedavi açısından yol gösterici olabilir.
Purpose: The objective of this study was to determine the depression, anxiety, and stress levels of operating room workers during the COVID-19 pandemic. Materials and Methods: The data were collected using the “Personal Information Form” and "Depression Anxiety Stress-21 (DASS-21)" scale. The personal information form consisted of eight questions including age, gender, profession, professional seniority, status of being diagnosed with COVID-19, being afraid of developing COVID-19, presence of chronic diseases and change in weight during the pandemic period. DASS-21 scale is a 4-point Likert type (never=0; always=3) scale and consists of seven questions with each predicting "depression, stress and anxiety dimensions". Results: A total of 253 volunteers with 161 (63.6%) being female and 92 (36.4%) male were included in this observational screening study. Anxiety score of female participants (5.65±4.44) was found to be statistically significantly higher compared to the male participants (3.94±4.68). Depression (5.97±4.41), anxiety (5.48±4.53) and stress (6.94±4.59) scores were significantly higher in the participants who were afraid of developing COVID-19. Depression, anxiety and stress scores were significantly higher in the participants with chronic diseases than in those without chronic diseases. Conclusion: The findings of our study indicate that the mean depression, anxiety and stress scores of the operating room personnel were mild.