Katarzyna Dorota Zawada

Dr. Katarzyna Dorota Zawada

orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 November 2016 in Journal of the American Chemical Society
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KRKatarzyna Rybicka-Jasińska
Katarzyna Rybicka-Jasińska
WSWenqian Shan
Wenqian Shan
KZKatarzyna Dorota Zawada
Katarzyna Dorota Zawada
KKKarl M. Kadish
Karl M. Kadish
DGDorota Gryko
Dorota Gryko

28 December 2022 in Molecules
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NDNatalia Dobros
Natalia Dobros
KZKatarzyna Dorota Zawada
Katarzyna Dorota Zawada
Katarzyna ParadowskaKatarzyna Paradowska
Katarzyna Paradowska
Lavender is a valuable medicinal plant belonging to the Lamiaceae family. Currently 39 species are known, but only Lavandula angustifolia is a pharmacopoeial raw material. Lavender has a long history of medicinal use and mainly exhibits antioxidant, anti-inflammatory, sedative, antidepressant, spasmolytic, anticholinesterases, antifungal and antibacterial properties. Used internally, it relieves symptoms of mental stress and insomnia and supports digestion. Topical use of lavender in aromatherapy, neuralgia and antiseptics is also known. The constant interest in lavender, and in particular in Lavandula angustifolia, in the field of medicine and pharmacy is evidenced by the growing number of publications. In view of so many studies, it seems important to review traditional and modern extraction techniques that determine the chemical composition responsible for the antioxidant and anti-inflammatory effects of various extracts from the species of the Lavandula genus.

5 April 2022 in Antioxidants
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NDNatalia Dobros
Natalia Dobros
KZKatarzyna Dorota Zawada
Katarzyna Dorota Zawada
Katarzyna ParadowskaKatarzyna Paradowska
Katarzyna Paradowska
Lavender is a valuable perennial plant from the Lamiaceae family. It is grown mainly for its essential oil, but it also contains polar bioactive compounds such as polyphenols and coumarins. Their level depends on the species, cultivars, geographical origin, climatic conditions, harvest time and extraction method. The authors investigated the effect of several extraction procedures (maceration, decoction and ultrasound-assisted extraction) applied to three cultivars of Lavandula angustifolia (Betty’s Blue, Elizabeth, Hidcote) and two cultivars of Lavandula x intermedia (Grosso, Gros Bleu) on the yield of the polyphenolic compounds and antioxidant activity. HPLC analysis showed the presence of rosmarinic acid (2.52–10.82 mg/g), ferulic acid glucoside (2.94–8.67 mg/g), caffeic acid (1.70–3.10 mg/g), morin (1.02–13.63 mg/g), coumarin (1.01–5.97 mg/g) and herniarin (1.05–8.02 mg/g). The content of phenolic acids and flavonoids was higher in lavender, while the content of coumarins was higher in lavandin in all types of extracts. The antioxidant activity was determined by DPPH-EPR assay for antiradical properties (104.58–206.77 μmol Trolox/g) and FRAP assay for reducing properties (79.21–203.06 μmol Trolox/g). The obtained results showed that the cultivar is the dominant factor differentiating the samples. Still, the extraction method plays an important role in the final bioactive substances content and antioxidant properties of obtained extracts.

4 September 2020 in Molecules
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MBMariusz Banach
Mariusz Banach
MWMagdalena Wiloch
Magdalena Wiloch
KZKatarzyna Dorota Zawada
Katarzyna Dorota Zawada
WCWojciech Cyplik
Wojciech Cyplik
Wojciech KujawskiWojciech Kujawski
Wojciech Kujawski
Aronia fruits contain many valuable components that are beneficial to human health. However, fruits are characterized by significant variations in chemical composition dependent on the growing conditions and harvesting period. Therefore, there is a need to formulate the extracts with a precisely defined content of health-promoting substances. Aronia dry extracts (ADE) were prepared from frozen pomace applying water extraction, followed by purification and spray-drying. Subsequently, the content of anthocyanins, phenolic acids, and polyphenols was determined. The high-quality chokeberry pomace enabled obtaining extracts with anthocyanin content much higher than the typical market standards. Moreover, it was found that the antioxidant capacity of aronia extracts exceeded those found in other fruit preparations. Antioxidant and free-radical scavenging properties were evaluated using a 2,2′-diphenyl-1-picrylhydrazyl using Electron Paramagnetic Resonance (EPR) spectroscopy (DPPH-EPR) test and Oxygen Radical Absorbance Capacity (ORAC) assay. The inhibition of lipid peroxidation and the level of inflammatory markers have been also investigated using lipopolysaccharide (LPS)-stimulated RAW 264 cells. It was revealed that ADE standardized to 25% of anthocyanins depresses the level of markers of inflammation and lipid peroxidation (Interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), and malondialdehyde (MDA)) in in vitro conditions. Additionally, it was confirmed that ADE at all analyzed concentrations did not show any cytotoxic effect as demonstrated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.

24 May 2013 in Journal of the Science of Food and Agriculture
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MJMarta K Jamróz
Marta K Jamróz
Katarzyna ParadowskaKatarzyna Paradowska
Katarzyna Paradowska
KZKatarzyna Dorota Zawada
Katarzyna Dorota Zawada
KMKaterina Makarova
Katerina Makarova
SKSławomir Kaźmierski
Sławomir Kaźmierski
IWIwona Wawer
Iwona Wawer

23 March 2021 in Molecules
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BKBartosz Kruszewski
Bartosz Kruszewski
KZKatarzyna Dorota Zawada
Katarzyna Dorota Zawada
PKPiotr Karpiński
Piotr Karpiński
High-pressure homogenization (HPH) is one of the food-processing methods being tested for use in food preservation as an alternative to pasteurization. The effects of the HPH process on food can vary depending on the process parameters used and product characteristics. The study aimed to investigate the effect of pressure, the number of passes, and the inlet temperature of HPH processing on the quality of cloudy blackcurrant juice as an example of food rich in bioactive compounds. For this purpose, the HPH treatment (pressure of 50, 150, and 220 MPa; one, three, and five passes; inlet temperature at 4 and 20 °C) and the pasteurization of the juice were performed. Titratable acidity, pH, turbidity, anthocyanin, vitamin C, and total phenolics content, as well as colour, and antioxidant activity were measured. Heat treatment significantly decreased the quality of the juice. For processing of the juice, the best were the combinations of the following: one pass, the inlet temperature of 4 °C, any of the used pressures (50, 150, and 220 MPa); and one pass, the inlet temperature of 20 °C, and the pressure of 150 MPa. Vitamin C and anthocyanin degradation have been reported during the HPH. The multiple passes of the juice through the machine were only beneficial in increasing the antioxidant capacity but negatively affected the colour stability.