Transparent self-cleaning coatings for photovoltaic (PV) glass require an effective balance among contaminant removal, optical transparency, and environmental durability. In this study, octadecyltrichlorosilane-modified silica (OTS-SiO2) coatings were fabricated on glass substrates using a simple spray-deposition method, and the effects of initial SiO2 suspension concentration on surface morphology, wettability, droplet mobility, self-cleaning performance, and optical transmittance were systematically investigated. Increasing the SiO2 concentration promoted the development of particulate surface structures, enhanced water repellency, and reduced contact angle hysteresis, accompanied by improved droplet mobility and dust-removal performance. The OTS-SiO2-15 coating, prepared using a SiO2 concentration of 15 mg mL−1, achieved a water contact angle of 140 ± 1.6°, a sliding angle of 3.9 ± 1.5°, a dust-removal efficiency of 91.6%, and a visible-light transmittance of 90.6 ± 0.3%. Further increases in SiO2 concentration provided only limited improvements in droplet mobility and cleaning performance while substantially reducing optical transparency. Under mechanical impact, both sliding angle and contact angle hysteresis increased despite the retention of relatively high water contact angles, indicating deteriorated droplet mobility. When applied as photovoltaic cover glass, OTS-SiO2-15 maintained an initial power conversion efficiency (PCE) comparable to that of uncoated glass (8.41% versus 8.43%). After 40 days of outdoor exposure, the normalized PCE decreased by 4.6% for the coated configuration, compared with 10.8% for uncoated glass. These results demonstrate that spray-deposited OTS-SiO2 coatings can provide a practical balance among droplet mobility, self-cleaning performance, and optical transparency, supporting their potential application in photovoltaic glass protection.