Monitoring fetal heart rate (FHR) variability plays a fundamental role in fetal state assessment. Reliable FHR signal can be obtained from an invasive direct fetal electrocardiogram (FECG), but this is limited to labour. Alternative abdominal (indirect) FECG signals can be recorded during pregnancy and labour. Quality, however, is much lower and the maternal heart and uterine contractions provide sources of interference. Here, we present ten twenty-minute pregnancy signals and 12 five-minute labour signals. Abdominal FECG and reference direct FECG were recorded simultaneously during labour. Reference pregnancy signal data came from an automated detector and were corrected by clinical experts. The resulting dataset exhibits a large variety of interferences and clinically significant FHR patterns. We thus provide the scientific community with access to bioelectrical fetal heart activity signals that may enable the development of new methods for FECG signals analysis, and may ultimately advance the use and accuracy of abdominal electrocardiography methods.
Monitoring of uterine contraction activity is an important diagnostic tool used during both pregnancy and labour. The strain the pregnant uterus exerts on the maternal abdomen is measured via external tocography. However, limitation of this approach has caused the development of another technique-electrohysterography--which is based on the recording of electrical uterine activity. A computer-aided system is presented, which allows the recording of electrohysterographic signals from the maternal abdomen and their on-line analysis both in time and frequency domains. As a research material, we acquired 108 traces during a 24 h period before labour from a group of patients between 37 and 40 weeks of gestation. The comparison study between electrohysterography and tocography was carried out thanks to the possibility of simultaneous recording of mechanical and electrical uterine activities. The obtained results show that both methods demonstrate high agreement in relation to the number of contractions recognized as being consistent. However, their agreement in relation to the quantitative description of recognized patterns has appeared to be unacceptable to consider these methods as fully alternative. The appropriate way of further development of electrohysterography seems to be spectral analysis. Several spectral parameters describing electrophysiological properties of uterine muscle can be obtained by the use of electrohysterographic signals.
Atrial fibrillation (AF) is a serious heart arrhythmia leading to a significant increase of the risk for occurrence of ischemic stroke. Clinically, the AF episode is recognized in an electrocardiogram. However, detection of asymptomatic AF, which requires a long-term monitoring, is more efficient when based on irregularity of beat-to-beat intervals estimated by the heart rate (HR) features. Automated classification of heartbeats into AF and non-AF by means of the Lagrangian Support Vector Machine has been proposed. The classifier input vector consisted of sixteen features, including four coefficients very sensitive to beat-to-beat heart changes, taken from the fetal heart rate analysis in perinatal medicine. Effectiveness of the proposed classifier has been verified on the MIT-BIH Atrial Fibrillation Database. Designing of the LSVM classifier using very large number of feature vectors requires extreme computational efforts. Therefore, an original approach has been proposed to determine a training set of the smallest possible size that still would guarantee a high quality of AF detection. It enables to obtain satisfactory results using only 1.39% of all heartbeats as the training data. Post-processing stage based on aggregation of classified heartbeats into AF episodes has been applied to provide more reliable information on patient risk. Results obtained during the testing phase showed the sensitivity of 98.94%, positive predictive value of 98.39%, and classification accuracy of 98.86%.
18 April 2006 in IEEE Transactions on Biomedical Engineering
A method for comparison of two acquisition techniques that are applied in clinical practice to provide information on fetal condition is presented. The aim of this work was to evaluate the commonly used Doppler ultrasound technique for monitoring of mechanical activity of fetal heart. Accuracy of beat-to-beat interval determination together with its influence on indices describing the fetal heart rate (FHR) variability calculated automatically using computer-aided fetal monitoring system were examined. We considered the direct fetal electrocardiography as a reference technique because it ensures the highest possible accuracy of heart interval measurement, and additionally all the definitions of popular time domain parameters quantifying FHR variability formerly have been created using the fetal electrocardiogram. We evaluated the reliability of various so called short-term and long-term variability indices, when they are calculated automatically using the signal obtained via the Doppler US from a fetal monitor. The results proved that evaluation of the acquisition technique influence on fetal well-being assessment cannot be accomplished basing on direct measurements of heartbeats only. The more relevant is the estimation of accuracy of the variability indices, since analysis of their changes can significantly increase predictability of fetal distress
Background: The currently used fetal monitoring instrumentation that is based on Doppler ultrasound technique provides the fetal heart rate (FHR) signal with limited accuracy. It is particularly noticeable as significant decrease of clinically important feature - the variability of FHR signal. The aim of our work was to develop a novel efficient technique for processing of the ultrasound signal, which could estimate the cardiac cycle duration with accuracy comparable to a direct electrocardiography. Methods: We have proposed a new technique which provides the true beat-to-beat values of the FHR signal through multiple measurement of a given cardiac cycle in the ultrasound signal. The method consists in three steps: the dynamic adjustment of autocorrelation window, the adaptive autocorrelation peak detection and determination of beat-to-beat intervals. The estimated fetal heart rate values and calculated indices describing variability of FHR, were compared to the reference data obtained from the direct fetal electrocardiogram, as well as to another method for FHR estimation. Results: The results revealed that our method increases the accuracy in comparison to currently used fetal monitoring instrumentation, and thus enables to calculate reliable parameters describing the variability of FHR. Relating these results to the other method for FHR estimation we showed that in our approach a much lower number of measured cardiac cycles was rejected as being invalid. Conclusions: The proposed method for fetal heart rate determination on a beat-to-beat basis offers a high accuracy of the heart interval measurement enabling reliable quantitative assessment of the FHR variability, at the same time reducing the number of invalid cardiac cycle measurements.
1 October 2011 in Computer Methods and Programs in Biomedicine