Luca Vollero

Prof. Luca Vollero

Computer Systems and Bioinformatics Lab, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Roma, Italy
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Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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FDFederico D'Antoni
Federico D'Antoni
Fabrizio RussoFabrizio Russo
Fabrizio Russo
Luca AmbrosioLuca Ambrosio
Luca Ambrosio
LBLuca Bacco
Luca Bacco
Luca VolleroLuca Vollero
Luca Vollero
VDVincenzo Denaro
Vincenzo Denaro
Low Back Pain (LBP) is currently the first cause of disability in the world, with a significant socioeconomic burden. Diagnosis and treatment of LBP often involve a multidisciplinary, individualized approach consisting of several outcome measures and imaging data along with emerging technologies. The increased amount of data generated in this process has led to the development of methods related to artificial intelligence (AI), and to computer-aided diagnosis (CAD) in particular, which aim to assist and improve the diagnosis and treatment of LBP. In this manuscript, we have systematically reviewed the available literature on the use of CAD in the diagnosis and treatment of chronic LBP. A systematic research of PubMed, Scopus, and Web of Science electronic databases was performed. The search strategy was set as the combinations of the following keywords: “Artificial Intelligence”, “Machine Learning”, “Deep Learning”, “Neural Network”, “Computer Aided Diagnosis”, “Low Back Pain”, “Lumbar”, “Intervertebral Disc Degeneration”, “Spine Surgery”, etc. The search returned a total of 1536 articles. After duplication removal and evaluation of the abstracts, 1386 were excluded, whereas 93 papers were excluded after full-text examination, taking the number of eligible articles to 57. The main applications of CAD in LBP included classification and regression. Classification is used to identify or categorize a disease, whereas regression is used to produce a numerical output as a quantitative evaluation of some measure. The best performing systems were developed to diagnose degenerative changes of the spine from imaging data, with average accuracy rates >80%. However, notable outcomes were also reported for CAD tools executing different tasks including analysis of clinical, biomechanical, electrophysiological, and functional imaging data. Further studies are needed to better define the role of CAD in LBP care.

FDFederico D'Antoni
Federico D'Antoni
Fabrizio RussoFabrizio Russo
Fabrizio Russo
Luca AmbrosioLuca Ambrosio
Luca Ambrosio
Luca VolleroLuca Vollero
Luca Vollero
Gianluca VadalàGianluca Vadalà
Gianluca Vadalà
VDVincenzo Denaro
Vincenzo Denaro
Chronic Low Back Pain (LBP) is a symptom that may be caused by several diseases, and it is currently the leading cause of disability worldwide. The increased amount of digital images in orthopaedics has led to the development of methods related to artificial intelligence, and to computer vision in particular, which aim to improve diagnosis and treatment of LBP. In this manuscript, we have systematically reviewed the available literature on the use of computer vision in the diagnosis and treatment of LBP. A systematic research of PubMed electronic database was performed. The search strategy was set as the combinations of the following keywords: “Artificial Intelligence”, “Feature Extraction”, “Segmentation”, “Computer Vision”, “Machine Learning”, “Deep Learning”, “Neural Network”, “Low Back Pain”, “Lumbar”. Results: The search returned a total of 558 articles. After careful evaluation of the abstracts, 358 were excluded, whereas 124 papers were excluded after full-text examination, taking the number of eligible articles to 76. The main applications of computer vision in LBP include feature extraction and segmentation, which are usually followed by further tasks. Most recent methods use deep learning models rather than digital image processing techniques. The best performing methods for segmentation of vertebrae, intervertebral discs, spinal canal and lumbar muscles achieve Sørensen–Dice scores greater than 90%, whereas studies focusing on localization and identification of structures collectively showed an accuracy greater than 80%. Future advances in artificial intelligence are expected to increase systems’ autonomy and reliability, thus providing even more effective tools for the diagnosis and treatment of LBP.

26 August 2024 in IEEE Access
Verified
Journal Article
Open access
LBLuca Bacco
Luca Bacco
LPLorenzo Petrosino
Lorenzo Petrosino
DADomenico Arganese
Domenico Arganese
Luca VolleroLuca Vollero
Luca Vollero
MPMarco Papi
Marco Papi
Mario MeroneMario Merone
Mario Merone
The investigation focused on the prediction of stock prices amidst significant macroeconomic and geopolitical volatility, particularly targeting North-American and European banks in 2022 — a year marked by intense economic shocks, including inflation, geopolitical tensions, and supply chain disruptions. A multidimensional approach was employed, integrating advanced Artificial Intelligence (AI) techniques such as Recurrent Neural Networks (RNNs) and sentiment analysis, utilizing a comprehensive dataset that includes traditional financial metrics and sentiment-driven data from social media, specifically Twitter (recently renamed X). By employing LSTM and FinBERT models, the study revolved around several key analyses: assessing the impact of different market conditions across the US and EU; exploring the potential benefits of data aggregation from multiple banks within these markets; examining the influence of varying historical data spans on model performance; and integrating sentiment analysis to capture the nuanced influence of public sentiment on stock movements. The findings indicate that market-specific dynamics significantly affect the predictive models, with higher inter-bank correlation observed in the US compared to a more fragmented European market. Additionally, models incorporating recent data streams and public sentiments tend to outperform those relying on traditional, longer historical data.

Verified
Journal Article
Open access
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FLFrancesco Lodato
Francesco Lodato
NCNicola Colonna
Nicola Colonna
Giorgio PennazzaGiorgio Pennazza
Giorgio Pennazza
Salvatore PraticòSalvatore Praticò
Salvatore Praticò
Marco SantonicoMarco Santonico
Marco Santonico
Maurizio PollinoMaurizio Pollino
Maurizio Pollino
This study analyzes, through remote sensing techniques and innovative clouding services, the recent land use dynamics in the North-Roman littoral zone, an area where the latest development has witnessed an important reconversion of purely rural areas to new residential and commercial services. The survey area includes five municipalities and encompasses important infrastructure, such as the “Leonardo Da Vinci” Airport and the harbor of Civitavecchia. The proximity to the metropolis, supported by an efficient network of connections, has modified the urban and peri-urban structure of these areas, which were formerly exclusively agricultural. Hereby, urban expansion has been quantified by classifying Landsat satellite images using the cloud computing platform “Google Earth Engine” (GEE). Landsat multispectral images from 1985 up to 2020 were used for the diachronic analysis, with a five-yearly interval. In order to achieve a high accuracy of the final result, work was carried out along the temporal dimension of the images, selecting specific time windows for the creation of datasets, which were adjusted by the information related to the NDVI index variation through time. This implementation showed interesting improvements in the model performance for each year, suggesting the importance of the NDVI standard deviation parameter. The results showed an increase in the overall accuracy, being from 90 to 97%, with improvements in distinguishing urban surfaces from impervious surfaces. The final results highlighted a significant increase in the study area of the “Urban” and “Woodland” classes over the 35-year time span that was considered, being 67.4 km2 and 70.4 km2, respectively. The accurate obtained results have allowed us to quantify and understand the landscape transformations in the area of interest, with particular reference to the dynamics of urban development.

21 April 2022 in Bioengineering
Verified
Journal Article
Open access
PDF file
FDFederico D'Antoni
Federico D'Antoni
LPLorenzo Petrosino
Lorenzo Petrosino
FSFabiola Sgarro
Fabiola Sgarro
APAntonio Pagano
Antonio Pagano
Luca VolleroLuca Vollero
Luca Vollero
Mario MeroneMario Merone
Mario Merone
Background: Type 1 Diabetes Mellitus (T1D) is an autoimmune disease that can cause serious complications that can be avoided by preventing the glycemic levels from exceeding the physiological range. Straightforwardly, many data-driven models were developed to forecast future glycemic levels and to allow patients to avoid adverse events. Most models are tuned on data of adult patients, whereas the prediction of glycemic levels of pediatric patients has been rarely investigated, as they represent the most challenging T1D population. Methods: A Convolutional Neural Network (CNN) and a Long Short-Term Memory (LSTM) Recurrent Neural Network were optimized on glucose, insulin, and meal data of 10 virtual pediatric patients. The trained models were then implemented on two edge-computing boards to evaluate the feasibility of an edge system for glucose forecasting in terms of prediction accuracy and inference time. Results: The LSTM model achieved the best numeric and clinical accuracy when tested in the .tflite format, whereas the CNN achieved the best clinical accuracy in uint8. The inference time for each prediction was far under the limit represented by the sampling period. Conclusion: Both models effectively predict glucose in pediatric patients in terms of numerical and clinical accuracy. The edge implementation did not show a significant performance decrease, and the inference time was largely adequate for a real-time application.

14 May 2019
Verified
Book Chapter
Closed access
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LFLuca Faramondi
Luca Faramondi
GOGabriele Oliva
Gabriele Oliva
RSRoberto Setola
Roberto Setola
Luca VolleroLuca Vollero
Luca Vollero