Antonio Lanata-Flores

Dr. Antonio Lanata-Flores

orcid

Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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ALAntonio Lanata-Flores
Antonio Lanata-Flores
MBMarcelo Armijos Briones
Marcelo Armijos Briones
PSPablo Benítez Sellán
Pablo Benítez Sellán
PAPatricia Estefanía Ayala Aguirre
Patricia Estefanía Ayala Aguirre
This randomized, statistician-blinded, parallel-group clinical trial will compare the effectiveness of three bone-augmentation techniques applied to the posterior mandible using the cortical shell approach. Eighty-seven participants will be randomly allocated into three groups (autogenous, xenogeneic, or allogeneic cortical shells), each combined with a 1:1 mixture of autogenous bone chips and biomaterial. Participants may contribute one or two eligible posterior mandibular sites; however, the unit of analysis for the primary outcome will be the participant, using a participant-level summary (mean value when two sites are treated). The study is registered at ClinicalTrials.gov (Identifier: NCT06661447). Recruitment has not yet begun. The single primary endpoint is horizontal bone gain (mm) at 6 months, evaluated by cone-beam computed tomography (CBCT). Additional CBCT assessments at 3 and 12 months will be analyzed as secondary longitudinal outcomes. Volumetric and morphometric analyses will be performed through a standardized digital workflow integrating intraoral scanning, CBCT segmentation, and surface registration. Secondary outcomes will include bone density, surgical duration, and postoperative inflammation. Based on a previous CBCT-based randomized clinical trial with a related horizontal ridge-augmentation methodology, assuming a pooled standard deviation of approximately 1.12 mm and a clinically relevant between-group difference of 1.0 mm, 26 evaluable participants per group are required to achieve approximately 81.5% power for each prespecified primary comparison using a conservative two-sided α of 0.025 for sample-size planning. To allow for an anticipated 10% attrition rate, 29 participants will be recruited per group, resulting in a total planned sample of 87 participants. The primary analysis will use an ANCOVA model adjusted for baseline ridge width. This study aims to generate controlled, quantitative evidence on the volumetric and clinical performance of different cortical graft materials for posterior mandibular reconstruction. Trial registration ClinicalTrials.gov Identifier: NCT06661447. The registry record will be updated before recruitment begins.

Verified
Open access
PDF file
ALAntonio Lanata-Flores
Antonio Lanata-Flores
MBMarcelo Armijos Briones
Marcelo Armijos Briones
PSPablo Benítez Sellán
Pablo Benítez Sellán
PAPatricia Estefanía Ayala Aguirre
Patricia Estefanía Ayala Aguirre
This randomized, statistician-blinded, parallel-group clinical trial will compare the effectiveness of three bone-augmentation techniques applied to the posterior mandible using the cortical shell approach. Eighty-seven participants will be randomly allocated into three groups (autogenous, xenogeneic, or allogeneic cortical shells), each combined with a 1:1 mixture of autogenous bone chips and biomaterial. Participants may contribute one or two eligible posterior mandibular sites; however, the unit of analysis for the primary outcome will be the participant, using a participant-level summary (mean value when two sites are treated). The study is registered at ClinicalTrials.gov (Identifier: NCT06661447). Recruitment has not yet begun. The single primary endpoint is horizontal bone gain (mm) at 6 months, evaluated by cone-beam computed tomography (CBCT). Additional CBCT assessments at 3 and 12 months will be analyzed as secondary longitudinal outcomes. Volumetric and morphometric analyses will be performed through a standardized digital workflow integrating intraoral scanning, CBCT segmentation, and surface registration. Secondary outcomes will include bone density, surgical duration, and postoperative inflammation. Based on a previous CBCT-based randomized clinical trial with a related horizontal ridge-augmentation methodology, assuming a pooled standard deviation of approximately 1.12 mm and a clinically relevant between-group difference of 1.0 mm, 26 evaluable participants per group are required to achieve approximately 81.5% power for each prespecified primary comparison using a conservative two-sided α of 0.025 for sample-size planning. To allow for an anticipated 10% attrition rate, 29 participants will be recruited per group, resulting in a total planned sample of 87 participants. The primary analysis will use an ANCOVA model adjusted for baseline ridge width. This study aims to generate controlled, quantitative evidence on the volumetric and clinical performance of different cortical graft materials for posterior mandibular reconstruction. Trial registration ClinicalTrials.gov Identifier: NCT06661447. The registry record will be updated before recruitment begins.

5 October 2026 in Dentistry Journal
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Journal Article
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PSPablo Lenin Benitez Sellan
Pablo Lenin Benitez Sellan
MRMaría Paula Sánchez Rogel
María Paula Sánchez Rogel
CBCoraima Pouleth Sandoval Bravo
Coraima Pouleth Sandoval Bravo
ALAntonio Lanata-Flores
Antonio Lanata-Flores
MBMarcelo Armijos Briones
Marcelo Armijos Briones
TGThiago Oliveira Gamba
Thiago Oliveira Gamba
Background/Objectives: Intraoral scanners (IOS) are increasingly integrated into dental curricula, yet evidence on how brief structured training affects novice students remains limited, particularly in resource-constrained settings. This pilot quasi-experimental study evaluated the effect of a structured IOS training program on the self-reported perceptions of undergraduate dental students with no prior IOS experience. Methods: Twenty first- and third-semester students at the School of Dentistry, Universidad de Especialidades Espíritu Santo (Ecuador), completed a 5-item Likert-type questionnaire (1–9 scale) before and after a training program comprising theoretical instruction and typodont-based practical sessions using a TRIOS 3 scanner (3Shape, Copenhagen, Denmark). Paired Student’s t-tests and Wilcoxon signed-rank tests were used to compare pre- and post-training scores, and effect sizes (Cohen’s dz for paired samples) were calculated for each dimension. Results: Significant improvements were observed in all five perception dimensions (all p < 0.001): familiarity (mean difference: +3.45; dz = 1.50), comfort (+3.25; dz = 1.40), confidence (+3.70; dz = 1.54), perceived scan accuracy (+3.30; dz = 1.41), and software competence (+3.55; dz = 1.30). Conclusions: Within the constraints of a single-group pilot design, the training program was associated with increases in students’ self-reported perceptions across all five dimensions. These preliminary findings may inform, but do not by themselves justify, decisions on the curricular integration of IOS training. Controlled studies with objective performance outcomes, validated instruments and follow-up assessment are required.

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Open access
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ALAntonio Lanata-Flores
Antonio Lanata-Flores
MBMarcelo Armijos Briones
Marcelo Armijos Briones
PSPablo Benítez Sellán
Pablo Benítez Sellán
PAPatricia Estefanía Ayala Aguirre
Patricia Estefanía Ayala Aguirre
This randomized, statistician-blinded, parallel-group clinical trial will compare the effectiveness of three bone-augmentation techniques applied to the posterior mandible using the cortical shell approach. Eighty-seven participants will be randomly allocated into three groups (autogenous, xenogeneic, or allogeneic cortical shells), each combined with a 1:1 mixture of autogenous bone chips and biomaterial. Participants may contribute one or two eligible posterior mandibular sites; however, the unit of analysis for the primary outcome will be the participant, using a participant-level summary (mean value when two sites are treated). The study is registered at ClinicalTrials.gov (Identifier: NCT06661447). Recruitment has not yet begun. The single primary endpoint is horizontal bone gain (mm) at 6 months, evaluated by cone-beam computed tomography (CBCT). Additional CBCT assessments at 3 and 12 months will be analyzed as secondary longitudinal outcomes. Volumetric and morphometric analyses will be performed through a standardized digital workflow integrating intraoral scanning, CBCT segmentation, and surface registration. Secondary outcomes will include bone density, surgical duration, and postoperative inflammation. Based on a previous CBCT-based randomized clinical trial with a related horizontal ridge-augmentation methodology, assuming a pooled standard deviation of approximately 1.12 mm and a clinically relevant between-group difference of 1.0 mm, 26 evaluable participants per group are required to achieve approximately 81.5% power for each prespecified primary comparison using a conservative two-sided α of 0.025 for sample-size planning. To allow for an anticipated 10% attrition rate, 29 participants will be recruited per group, resulting in a total planned sample of 87 participants. The primary analysis will use an ANCOVA model adjusted for baseline ridge width. This study aims to generate controlled, quantitative evidence on the volumetric and clinical performance of different cortical graft materials for posterior mandibular reconstruction. Trial registration ClinicalTrials.gov Identifier: NCT06661447. The registry record will be updated before recruitment begins.

Verified
Open access
PDF file
ALAntonio Lanata-Flores
Antonio Lanata-Flores
MBMarcelo Armijos Briones
Marcelo Armijos Briones
PSPablo Benítez Sellán
Pablo Benítez Sellán
PAPatricia Estefanía Ayala Aguirre
Patricia Estefanía Ayala Aguirre
This randomized, statistician-blinded, parallel-group clinical trial will compare the effectiveness of three bone-augmentation techniques applied to the posterior mandible using the cortical shell approach. Eighty-seven participants will be randomly allocated into three groups (autogenous, xenogeneic, or allogeneic cortical shells), each combined with a 1:1 mixture of autogenous bone chips and biomaterial. Participants may contribute one or two eligible posterior mandibular sites; however, the unit of analysis for the primary outcome will be the participant, using a participant-level summary (mean value when two sites are treated). The study is registered at ClinicalTrials.gov (Identifier: NCT06661447). Recruitment has not yet begun. The single primary endpoint is horizontal bone gain (mm) at 6 months, evaluated by cone-beam computed tomography (CBCT). Additional CBCT assessments at 3 and 12 months will be analyzed as secondary longitudinal outcomes. Volumetric and morphometric analyses will be performed through a standardized digital workflow integrating intraoral scanning, CBCT segmentation, and surface registration. Secondary outcomes will include bone density, surgical duration, and postoperative inflammation. Based on a previous CBCT-based randomized clinical trial with a related horizontal ridge-augmentation methodology, assuming a pooled standard deviation of approximately 1.12 mm and a clinically relevant between-group difference of 1.0 mm, 26 evaluable participants per group are required to achieve approximately 81.5% power for each prespecified primary comparison using a conservative two-sided α of 0.025 for sample-size planning. To allow for an anticipated 10% attrition rate, 29 participants will be recruited per group, resulting in a total planned sample of 87 participants. The primary analysis will use an ANCOVA model adjusted for baseline ridge width. This study aims to generate controlled, quantitative evidence on the volumetric and clinical performance of different cortical graft materials for posterior mandibular reconstruction. Trial registration ClinicalTrials.gov Identifier: NCT06661447. The registry record will be updated before recruitment begins.

Verified
Open access
PDF file
ALAntonio Lanata-Flores
Antonio Lanata-Flores
MBMarcelo Armijos Briones
Marcelo Armijos Briones
PSPablo Benítez Sellán
Pablo Benítez Sellán
PAPatricia Estefanía Ayala Aguirre
Patricia Estefanía Ayala Aguirre
This randomized, statistician-blinded, parallel-group clinical trial will compare the effectiveness of three bone-augmentation techniques applied to the posterior mandible using the cortical shell approach. Eighty-seven participants will be randomly allocated into three groups (autogenous, xenogeneic, or allogeneic cortical shells), each combined with a 1:1 mixture of autogenous bone chips and biomaterial. Participants may contribute one or two eligible posterior mandibular sites; however, the unit of analysis for the primary outcome will be the participant, using a participant-level summary (mean value when two sites are treated). The study is registered at ClinicalTrials.gov (Identifier: NCT06661447). Recruitment has not yet begun. The single primary endpoint is horizontal bone gain (mm) at 6 months, evaluated by cone-beam computed tomography (CBCT). Additional CBCT assessments at 3 and 12 months will be analyzed as secondary longitudinal outcomes. Volumetric and morphometric analyses will be performed through a standardized digital workflow integrating intraoral scanning, CBCT segmentation, and surface registration. Secondary outcomes will include bone density, surgical duration, and postoperative inflammation. Based on a previous CBCT-based randomized clinical trial with a related horizontal ridge-augmentation methodology, assuming a pooled standard deviation of approximately 1.12 mm and a clinically relevant between-group difference of 1.0 mm, 26 evaluable participants per group are required to achieve approximately 81.5% power for each prespecified primary comparison using a conservative two-sided α of 0.025 for sample-size planning. To allow for an anticipated 10% attrition rate, 29 participants will be recruited per group, resulting in a total planned sample of 87 participants. The primary analysis will use an ANCOVA model adjusted for baseline ridge width. This study aims to generate controlled, quantitative evidence on the volumetric and clinical performance of different cortical graft materials for posterior mandibular reconstruction. Trial registration ClinicalTrials.gov Identifier: NCT06661447. The registry record will be updated before recruitment begins.