A small scale (~270 Nm³·h⁻¹) vacuum pressure swing adsorption (VPSA) air separation system was established in Qinghai Province (in China) with an altitude of 3800 m, which was used to supply oxygen for relieving the hypoxia. The effects of adsorption and desorption time, purge and pressure equalization step and feed temperature on the performance of the process were investigated by performing experiments under plateau special conditions. Results showed that pressure equalization and intermittent purge steps could effectively improve the performance of the VPSA process. The system could produce 270 Nm³·h⁻¹ of 90% O₂ with 62.6% oxygen recovery from compressed air. The maximum productivity and minimum energy consumption with pressure ratio of 160:42 for ~90% O₂ were 121.7 L·h⁻¹·kg⁻¹ and 0.55 kWh·Nm⁻³, respectively.

Rapid-cycle pressure swing adsorption (PSA) with small adsorbents particles is intended to improve mass transfer rate and productivity. However, the mass transfer mechanisms are changed with reduction of particle size during rapid-cycle adsorption process. A heat and mass transfer model of rapid-cycle PSA air separation process employing small LiLSX zeolite particles is developed and experimentally validated to numerically analyze the effects of mass transfer resistances on the characteristics of cyclic adsorption process. Multicomponent Langmuir model and linear driving force model are employed for characterizing the adsorption equilibrium and kinetic. The results of numerical analysis demonstrate that the dominant mass transfer resistance of small adsorbents particles is a combination of film resistance, axial dispersion effect and macropore diffusion resistance. The oxygen purity, recovery and productivity of the product are overestimated by ~2–4% when the effect of axial dispersion on mass transfer is ignored. As particle size decreases, the front of nitrogen-adsorbed concentration and gas temperature become sharp, which effectively improves the performance. However, the adverse effect of axial dispersion on the mass transfer becomes significant at very small particles conditions. It is nearly identical shapes of nitrogen concentration and gas temperature profiles after adsorption and desorption steps. The profiles are pushed forward near the production end with an increase in bed porosities. The optimal oxygen recovery and productivity are achieved with a particle diameter of 0.45 mm and bed porosity of 0.39 during the PSA process.