This paper provides an overview of collaborative robotics towards manufacturing applications. Over the last decade, the market has seen the introduction of a new category of robots—collaborative robots (or “cobots”)—designed to physically interact with humans in a shared environment, without the typical barriers or protective cages used in traditional robotics systems. Their potential is undisputed, especially regarding their flexible ability to make simple, quick, and cheap layout changes; however, it is necessary to have adequate knowledge of their correct uses and characteristics to obtain the advantages of this form of robotics, which can be a barrier for industry uptake. The paper starts with an introduction of human–robot collaboration, presenting the related standards and modes of operation. An extensive literature review of works published in this area is undertaken, with particular attention to the main industrial cases of application. The paper concludes with an analysis of the future trends in human–robot collaboration as determined by the authors.

This paper presents the development of and clinical tests on NeReBot (NEuroREhabilitation roBOT): a three degrees-of-freedom (DoF), wire-driven robot for poststroke upper-limb rehabilitation. Basically, the robot consists of a set of three wires independently driven by three electric motors. The wires are connected to the patient's upper limb by means of a splint and are supported by a transportable frame, located above the patient. By controlling wire length, rehabilitation treatment (based on the passive or active-assistive spatial motion of the limb) can be delivered over a wide working space. The arm trajectory is set by the therapist through a very simple teaching-by-showing procedure, enabling most common ldquohands onrdquo therapy exercises to be reproduced by the robot. Compared to other rehabilitation robots, NeReBot offers the advantages of a low-cost mechanical structure, intrinsically safe treatment thanks to the use of wires, high acceptability by the patient, who does not feel constrained by an ldquoindustrial-likerdquo robot, transportability (it can be easily placed aside a hospital bed and/or a wheelchair), and a good trade-off between low number of DoF and spatial performance. These features and the very encouraging results of the first clinical trials make the NeReBot a good candidate for adoption in the rehabilitation treatment of subacute stroke survivors. Clinical trials were performed with a 12-patient experimental group and a 12-patient control group. Resulted that the patients who received robotic therapy in addition to conventional therapy showed greater reductions in motor impairment (in terms of Medical Research Council score, the upper limb subsection of the Fugl-Meyer score, and the Motor Status Score) and improvements in functional abilities (as measured by the Functional Independence Measure and its motor component). No adverse effects occurred and the robotic approach was very well accepted. According to these results, the NeReBot therapy may efficaciously complement standard poststroke multidisciplinary rehabilitation and offer novel therapeutic strategies for neurological rehabilitation.

Introduction. The role of robotics in poststroke patients’ rehabilitation has been investigated intensively. This paper presents the state-of-the-art and the possible future role of robotics in poststroke rehabilitation, for both upper and lower limbs.Materials and Methods. We performed a comprehensive search of PubMed, Cochrane, and PeDRO databases using as keywords “robot AND stroke AND rehabilitation.”Results and Discussion. In upper limb robotic rehabilitation, training seems to improve arm function in activities of daily living. In addition, electromechanical gait training after stroke seems to be effective. It is still unclear whether robot-assisted arm training may improve muscle strength, and which electromechanical gait-training device may be the most effective for walking training implementation.Conclusions. In the field of robotic technologies for stroke patients’ rehabilitation we identified currently relevant growing points and areas timely for developing research. Among the growing points there is the development of new easily transportable, wearable devices that could improve rehabilitation also after discharge, in an outpatient or home-based setting. For developing research, efforts are being made to establish the ideal type of treatment, the length and amount of training protocol, and the patient’s characteristics to be successfully enrolled to this treatment.

The successful motor rehabilitation of stroke patients requires early intensive and task-specific therapy. A recent Cochrane Review, although based on a limited number of randomized controlled trials (RCTs), showed that early robotic training of the upper limb (i.e., during acute or subacute phase) can enhance motor learning and improve functional abilities more than chronic-phase training. In this article, a new subacute-phase RCT with the Neuro-Rehabilitation-roBot (NeReBot) is presented. While in our first study we used the NeReBot in addition to conventional therapy, in this new trial we used the same device in substitution of standard proximal upper-limb rehabilitation. With this protocol, robot patients achieved similar reductions in motor impairment and enhancements in paretic upper-limb function to those gained by patients in a control group. By analyzing these results and those of previous studies, we hypothesize a new robotic protocol for acute and subacute stroke patients based on both treatment modalities (in addition and in substitution).

In this paper, we discuss robot-mediated neurorehabilitation as a significant emerging field in clinical medicine. Stroke rehabilitation is advancing toward more integrated processes, using robotics to facilitate this integration. Rehabilitation approaches have tremendous value in reducing long-term impairments in stroke patients during hospitalization and after discharge, of which robotic systems are a new modality that can provide more effective rehabilitation. The function of robotics in rehabilitative interventions has been examined extensively, generating positive yet not completely satisfactory clinical results. This article presents state-of-the-art robotic systems and their prospective function in poststroke rehabilitation of the upper and lower limbs.