Dr. Rosalba Senese

Professor Rosalba Senese is an Associate Professor of Physiology at the University of Campania “Luigi Vanvitelli.” Professor Senese's scientific activity is part of the general theme of molecular and cellular mechanisms involved in the control of energy homeostasis, with particular attention to the regulation exerted by iodothyronines. In the first years of research activity, she investigated the mechanisms through which thyroid hormones are able to induce, at the mitochondrial level, an uncoupling between the electron transport and ATP synthesis, and thus regulate heat production at the cell level. Her studies contributed to the demonstration that Uncoupling Protein 3 (UCP3) is a molecular determinant of the calorigenic effect of T3 and that the mechanism of regulation of UCP3 expression by T3 is species-specific. More recently, her studies have revealed other important actions of T2 on visceral white adipose tissue, aimed at counteracting the inflammatory state inevitably associated with hyperlipidic diets. Professor Senese has published 60 papers in international journals, accumulating a total of 1536 citations and achieving an H-index of 24. Additionally, she serves as a referee for various international journals and is currently an editor for a research topic within Frontiers in Physiology.