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(1) Background: The volume-viscosity swallow test (V-VST) is a clinical tool for screening and diagnosis of oropharyngeal dysphagia (OD). Our aims were to examine the clinical utility of the V-VST against videofluoroscopy (VFS) or fiberoptic endoscopic evaluation of swallow (FEES) and to map the V-VST usage with patients at risk of OD across the years since it was described for the first time, carrying a systematic and a scoping review. (2) Methods: We performed both a systematic review (SR) including studies that look at the diagnostic test accuracy, and a scoping review (ScR) with articles published from September 2008 to May 2020. Searches were done in different databases, including PubMed and EMBASE from September 2008 until May 2020, and no language restrictions were applied. A meta-analysis was done in the SR to assess the psychometric properties of the V-VST. Quality of studies was assessed by Dutch Cochrane, QUADAS, GRADE (SR), and STROBE (ScR) criteria. The SR protocol was registered on PROSPERO (registration: CRD42020136252). (3) Results: For the diagnostic accuracy SR: four studies were included. V-VST had a diagnostic sensitivity for OD of 93.17%, 81.39% specificity, and an inter-rater reliability Kappa = 0.77. Likelihood ratios (LHR) for OD were 0.08 (LHR–) and 5.01 (LHR+), and the diagnostic odds ratio for OD was 51.18. Quality of studies in SR was graded as high with low risk of bias. In the ScR: 34 studies were retrieved. They indicated that V-VST has been used internationally to assess OD’s prevalence and complications. (4) Conclusions: The V-VST has strong psychometric properties and valid endpoints for OD in different phenotypes of patients. Our results support its utility in the screening and clinical diagnosis and management of OD.
Stephanie A. Riera; Sergio Marin; Mateu Serra-Prat; Noemí Tomsen; Viridiana Arreola; Omar Ortega; Margaret Walshe; Pere Clavé. A Systematic and a Scoping Review on the Psychometrics and Clinical Utility of the Volume-Viscosity Swallow Test (V-VST) in the Clinical Screening and Assessment of Oropharyngeal Dysphagia. Foods 2021, 10, 1900 .
AMA StyleStephanie A. Riera, Sergio Marin, Mateu Serra-Prat, Noemí Tomsen, Viridiana Arreola, Omar Ortega, Margaret Walshe, Pere Clavé. A Systematic and a Scoping Review on the Psychometrics and Clinical Utility of the Volume-Viscosity Swallow Test (V-VST) in the Clinical Screening and Assessment of Oropharyngeal Dysphagia. Foods. 2021; 10 (8):1900.
Chicago/Turabian StyleStephanie A. Riera; Sergio Marin; Mateu Serra-Prat; Noemí Tomsen; Viridiana Arreola; Omar Ortega; Margaret Walshe; Pere Clavé. 2021. "A Systematic and a Scoping Review on the Psychometrics and Clinical Utility of the Volume-Viscosity Swallow Test (V-VST) in the Clinical Screening and Assessment of Oropharyngeal Dysphagia." Foods 10, no. 8: 1900.
There is a two-way relationship between frailty and depression, but the mechanisms by which one may influence the other are not well understood. The objective of this study was to evaluate the relationship between psychosocial factors and frailty in community-dwelling aged populations with depression. Observational cross-sectional study. 5 primary care centres. Community-dwelling subjects with depression aged ≥70 years. Frailty status was established according to Fried criteria, depression and depression severity were evaluated by DSM-IV criteria and the Hamilton Depression Rating Scale, respectively, and psychosocial factors were assessed using the Gijón Social-Familial Evaluation Scale and ad hoc questionnaires. Recruited were 338 subjects (mean age 77.2 years), 82% women and 36.1% rated as frail. A dose–response relationship was observed between depression severity and frailty risk. Widowhood was a risk factor for frailty, while a higher educational level, home internet, stairs in the home, and an active social life had a protective effect. A multivariate analysis showed that age, number of drugs, and depression severity were independent risk factors for frailty, while an active social life was a protective factor. The severity of depressive symptoms showed higher association with frailty than other clinical and socio-demographic characteristics. In depressed elderly subjects, frailty is associated with psychologiocal factors such as the intensity of depressive symptoms and with social factors such as education level, widowhood, loneliness, and limited social life. More research is required to better understand the modifiable psychological risk factors for frailty. Existe una relación bidireccional entre la fragilidad y la depresión en la población anciana. El objetivo de este estudio fue evaluar la relación entre los factores psicosociales y la fragilidad en ancianos de la comunidad con depresión. Estudio observacional transversal. Cinco centros de atención primaria. Ancianos ≥ 70 años de la comunidad con depresión. La fragilidad se estableció de acuerdo con los criterios de Fried, la depresión y la gravedad de la depresión se evaluaron mediante los criterios DSM-IV y la Escala de Hamilton, respectivamente, y los factores psicosociales se evaluaron utilizando la Escala de Evaluación Social-Familiar de Gijón y cuestionarios ad hoc. Se reclutaron 338 sujetos (edad media 77 años), 82% mujeres y 36,1% frágiles. Se observó una relación dosis-respuesta entre la gravedad de la depresión y el riesgo de fragilidad. La viudez era un factor de riesgo para la fragilidad, mientras que un nivel educativo más alto, internet en el hogar, escaleras en el hogar y una vida social activa tenían un efecto protector. El análisis multivariado mostró que la edad, el número de medicamentos y la gravedad de la depresión eran factores de riesgo independientes para la fragilidad, mientras que una vida social activa era un factor protector. En ancianos con depresión la fragilidad se asocia con factores psicológicos como la intensidad de los síntomas depresivos y con factores sociales como el nivel de estudios, la viudez, la soledad o la escasa vida social. Se requiere más investigación para comprender mejor los factores de riesgo psicológicos modificables de fragilidad.
Joaquim Oyon; Mateu Serra-Prat; Mariona Ferrer; Antònia Llinares; Núria Pastor; Esther Limón; Tatiana Rejón; Sara Ramírez; Alba Salietti. Psychosocial factors associated with frailty in the community-dwelling aged population with depression. A cross-sectional study. Atención Primaria 2021, 53, 102048 .
AMA StyleJoaquim Oyon, Mateu Serra-Prat, Mariona Ferrer, Antònia Llinares, Núria Pastor, Esther Limón, Tatiana Rejón, Sara Ramírez, Alba Salietti. Psychosocial factors associated with frailty in the community-dwelling aged population with depression. A cross-sectional study. Atención Primaria. 2021; 53 (5):102048.
Chicago/Turabian StyleJoaquim Oyon; Mateu Serra-Prat; Mariona Ferrer; Antònia Llinares; Núria Pastor; Esther Limón; Tatiana Rejón; Sara Ramírez; Alba Salietti. 2021. "Psychosocial factors associated with frailty in the community-dwelling aged population with depression. A cross-sectional study." Atención Primaria 53, no. 5: 102048.
Incidence and clinical characteristics of foot pressure ulcers (FPU) in hospitalized elderly patients are not well known. The aim of the study was to determine the incidence of FPU during hospitalization, to describe main FPU characteristics and to assess main risk factors for FPU in hospitalised elderly subjects. An observational prospective study was performed in which patients 65 years or older admitted to Vascular Surgery, Orthopaedic or Geriatric departments were followed from admission to discharge. Trained nurses evaluated all recruited patients on a daily basis for possible FPU. Main characteristics of the patient (age, sex and co-morbidities) and the ulcer (location, grade) were registered. 299 patients were recruited (62.2% women, mean age 82.3 years, mean number of co-morbidities 2.8). Prevalence of FPU was 30.1% at admission and 73.9% at discharge. Incidence of FPU during hospitalization was 9.5 new FPU/100 person-day. 97.0% of the new FPU were grade 1 (erythema) and the most common locations were in the heel (57.6%), the external lateral part of the foot (13.1%), and the hallux of the fist toe (11.8%). Apart from immobility, main risk factors for FPU are age, geriatric residence origin and not able to outdoor life. FPU has a high incidence among hospitalised elderly patients; most of them are grade 1 and located in the heel. More attention must be paid in the prevention of pressure ulcers in hospitalized frail subjects. No se conocen bien la incidencia y las características clínicas de las úlceras por presión (UPP) en el pie en los pacientes mayores hospitalizados. El objetivo de este estudio fue determinar la incidencia de las UPP durante la hospitalización, describir sus principales características, y evaluar los principales factores de riesgo en los sujetos mayores hospitalizados. Se llevó a cabo un estudio prospectivo observacional en el que se realizó un seguimiento desde el ingreso al alta de los pacientes mayores de 65 años ingresados en las unidades de cirugía vascular, traumatología o geriatría. Las enfermeras experimentadas evaluaron diariamente a todos los pacientes reclutados en busca de una posible UPP. Se registraron las características principales del paciente (edad, sexo y comorbilidades) y de la úlcera (localización y grado). Se reclutaron 299 pacientes (62,2% mujeres, con una edad media de 82,3 años, y número medio de comorbilidades de 2,8). La prevalencia de UPP fue del 30,1% en el momento del ingreso, y del 73,9% al producirse el alta. La incidencia de UPP durante la hospitalización fue de 9,5 nuevas UPP/100 personas/día. El 97% de las nuevas UPP fueron de grado 1 (eritema), y las localizaciones más comunes fueron el talón (57,6%), la parte lateral externa del pie (13,1%) y el hallux del dedo gordo (11,8%). Aparte de la inmovilidad, los factores principales de riesgo de UPP fueron la edad, la residencia geriátrica como origen y la imposibilidad de realizar actividades en el exterior. Las UPP tienen una gran incidencia entre los pacientes mayores hospitalizados, siendo la mayoría de ellas de grado 1 con localización en el talón. Deberá prestarse más atención a la prevención de las UPP en los sujetos frágiles hospitalizados.
S. Garcia; J. Alòs; J. Guallar; M. Viu; M. Serra-Prat. Prevalence, incidence and risk factors for foot pressure ulcers in hospitalized elderly patients. An observational and prospective study. Journal of Healthcare Quality Research 2020, 36, 27 -33.
AMA StyleS. Garcia, J. Alòs, J. Guallar, M. Viu, M. Serra-Prat. Prevalence, incidence and risk factors for foot pressure ulcers in hospitalized elderly patients. An observational and prospective study. Journal of Healthcare Quality Research. 2020; 36 (1):27-33.
Chicago/Turabian StyleS. Garcia; J. Alòs; J. Guallar; M. Viu; M. Serra-Prat. 2020. "Prevalence, incidence and risk factors for foot pressure ulcers in hospitalized elderly patients. An observational and prospective study." Journal of Healthcare Quality Research 36, no. 1: 27-33.
ObjectivesTo assess the healthcare costs associated with poststroke oropharyngeal dysphagia (OD) and its complications (malnutrition, dehydration, pneumonia and death).DesignSystematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations.Data sourcesMEDLINE, Embase and the National Health Service Economic Evaluation Database were searched up to 31 December 2019.ParticipantsPatients with poststroke.Primary outcome measuresThe costs associated to poststroke OD and its complications.Data analysisData were synthetised narratively, quality evaluation was done using an adaptation of Drummond’s checklist and Grading of Recommendations Assessment, Development and Evaluation recommendations were used to assess strength of evidence.ResultsA total of 166 articles were identified, of which 10 studies were included. The cost of OD during the hospitalisation was assessed in four studies. One prospective study showed an increase of US$6589 for patients requiring tube feeding. Two retrospective studies found higher costs for those patients who developed OD, (US$7329 vs US$5939) among patients with haemorrhagic stroke transferred to inpatient rehabilitation and an increase of €3000 (US$3950) and SFr14 000 (US$15 300) in hospitalisation costs. One study did not found OD as a predictor for total medical costs in the multivariate analysis. One retrospective study showed an increase of US$4510 during the first year after stroke for those patients with OD. For pneumonia, five retrospective studies showed an increase in hospitalisation costs after stroke of between US$1456 and US$27 633. One prospective study showed an increase in hospitalisation costs during 6 months after stroke in patients at high malnutrition risk. Strength of evidence was considered moderate for OD and pneumonia and low for malnutrition.ConclusionsThis systematic review shows moderate evidence towards higher costs for those patients who developed OD after stroke. The available literature is heterogeneous, and some important aspects have not been studied yet. Further studies are needed to define the specific cost of poststroke OD.PROSPERO registration numberCRD42018099977.
Sergio Marin; Mateu Serra-Prat; Omar Ortega; Pere Clavé. Healthcare-related cost of oropharyngeal dysphagia and its complications pneumonia and malnutrition after stroke: a systematic review. BMJ Open 2020, 10, e031629 .
AMA StyleSergio Marin, Mateu Serra-Prat, Omar Ortega, Pere Clavé. Healthcare-related cost of oropharyngeal dysphagia and its complications pneumonia and malnutrition after stroke: a systematic review. BMJ Open. 2020; 10 (8):e031629.
Chicago/Turabian StyleSergio Marin; Mateu Serra-Prat; Omar Ortega; Pere Clavé. 2020. "Healthcare-related cost of oropharyngeal dysphagia and its complications pneumonia and malnutrition after stroke: a systematic review." BMJ Open 10, no. 8: e031629.
Background: In aged populations, muscle strength depends more on muscle quality than on muscle quantity, while all three are criteria for the diagnosis of sarcopenia. Intracellular water content (ICW) in lean mass (LM) has been proposed as an indicator of muscle quality related to muscle strength in older people. Objectives: To evaluate the relationship between the ICW/LM ratio, muscle strength and indicators of functional performance in obese older adults, and to assess the value of the ICW/LM ratio as an indicator of muscle quality. Methodology: Design: cross-sectional study. Population: persons aged 65–75 years with a body mass index of 30–39 kg/m2. ICW and LM were estimated by bioelectrical impedance. Hand grip, gait speed, unipedal stance test, timed up-and-go (TUG) test, Barthel score and frailty (Fried criteria) were assessed. Sarcopenia was established according to EWGSOP2 criteria. Results: Recruited were 305 subjects (66% women), mean age 68 years. The ICW/LM ratio correlated with the TUG test, gait speed and grip strength, and was also associated with sex, the unipedal stance test and frailty. Independently of age, sex and muscle mass, the ICW/LM ratio was related with gait speed, the TUG test and unipedal stance capacity. One person (0.3%) had sarcopenia defined as low muscle strength and low muscle mass, while 25 people (8.2%) had sarcopenia defined as low muscle strength and poor muscle quality (ICW/LM). With this last definition, sarcopenia was related to frailty, gait speed and the TUG test. Conclusions: ICW content in LM could be a useful muscle quality indicator for defining sarcopenia. However, more studies are required to confirm our findings for other populations.
Mateu Serra-Prat; Isabel Lorenzo; Mònica Papiol; Elisabet Palomera; Maria Bartolomé; Eulogio Pleguezuelos; Emili Burdoy. Intracellular Water Content in Lean Mass as an Indicator of Muscle Quality in an Older Obese Population. Journal of Clinical Medicine 2020, 9, 1580 .
AMA StyleMateu Serra-Prat, Isabel Lorenzo, Mònica Papiol, Elisabet Palomera, Maria Bartolomé, Eulogio Pleguezuelos, Emili Burdoy. Intracellular Water Content in Lean Mass as an Indicator of Muscle Quality in an Older Obese Population. Journal of Clinical Medicine. 2020; 9 (5):1580.
Chicago/Turabian StyleMateu Serra-Prat; Isabel Lorenzo; Mònica Papiol; Elisabet Palomera; Maria Bartolomé; Eulogio Pleguezuelos; Emili Burdoy. 2020. "Intracellular Water Content in Lean Mass as an Indicator of Muscle Quality in an Older Obese Population." Journal of Clinical Medicine 9, no. 5: 1580.
Adherence of elderly population to physical exercise programs is scarce. Our objective was to identify perceived barriers and facilitators reported by obese older adults to engage in regular physical activity and to explore their association with poor active life. A cross-sectional survey was performed. One hundred and eighty community-dwelling, obese (BMI > 30 and < 40), 65–75-year-old adults were recruited. Participants were asked to answer the “barriers and facilitators for exercise” survey and to report their usual physical activity. Approximately 60% of obese older adults engaged in poor physical activity. Lack of motivation/willpower and pain were the most reported reasons not to exercise, but significant differences exist between sexes. Women were more likely not to exercise due to pain or fatigue, while lack of time was more frequently reported in men. Age, female sex, pain, and lack of motivation and willpower were independent risk factors for not exercising, while the desire to go outdoors and to the nature was an independent protective factor for exercising. There are some important barriers which prevent obese older people to exercise. These aspects should be taken into account when designing physical exercise programs for the elderly, since considering patient’s preferences and personal limitations would improve adherence to such programs and their effectiveness.
Raquel Sebio; Mateu Serra-Prat. Opinion of community-dwelling elderly obese about the barriers and facilitators to engage physical exercise. Sport Sciences for Health 2020, 16, 411 -418.
AMA StyleRaquel Sebio, Mateu Serra-Prat. Opinion of community-dwelling elderly obese about the barriers and facilitators to engage physical exercise. Sport Sciences for Health. 2020; 16 (3):411-418.
Chicago/Turabian StyleRaquel Sebio; Mateu Serra-Prat. 2020. "Opinion of community-dwelling elderly obese about the barriers and facilitators to engage physical exercise." Sport Sciences for Health 16, no. 3: 411-418.
Mateu Serra-Prat; Elisabet Palomera. Muscle Strength, Sarcopenia and Frailty Associations with Balance and Gait Parameters: A Cross-sectional Study. European Journal of Geriatrics and Gerontology 2019, 1, 61 -66.
AMA StyleMateu Serra-Prat, Elisabet Palomera. Muscle Strength, Sarcopenia and Frailty Associations with Balance and Gait Parameters: A Cross-sectional Study. European Journal of Geriatrics and Gerontology. 2019; 1 (2):61-66.
Chicago/Turabian StyleMateu Serra-Prat; Elisabet Palomera. 2019. "Muscle Strength, Sarcopenia and Frailty Associations with Balance and Gait Parameters: A Cross-sectional Study." European Journal of Geriatrics and Gerontology 1, no. 2: 61-66.
Water, the main component of the body, is distributed in the extracellular and intracellular compartments. Water exchange between these compartments is mainly governed by osmotic pressure. Extracellular water osmolarity must remain within very narrow limits to be compatible with life. Older adults lose the thirst sensation and the ability to concentrate urine, and this favours increased extracellular osmolarity (hyperosmotic stress). This situation, in turn, leads to cell dehydration, which has severe consequences for the intracellular protein structure and function and, ultimately, results in cell damage. Moreover, the fact that water determines cell volume may act as a metabolic signal, with cell swelling acting as an anabolic signal and cell shrinkage acting as a catabolic signal. Ageing also leads to a progressive loss in muscle mass and strength. Muscle strength is the main determinant of functional capacity, and, in elderly people, depends more on muscle quality than on muscle quantity (or muscle mass). Intracellular water content in lean mass has been related to muscle strength, functional capacity, and frailty risk, and has been proposed as an indicator of muscle quality and cell hydration. This review aims to assess the role of hyperosmotic stress and cell dehydration on muscle function and frailty.
Isabel Lorenzo; Mateu Serra-Prat; Juan Carlos Yébenes. The Role of Water Homeostasis in Muscle Function and Frailty: A Review. Nutrients 2019, 11, 1857 .
AMA StyleIsabel Lorenzo, Mateu Serra-Prat, Juan Carlos Yébenes. The Role of Water Homeostasis in Muscle Function and Frailty: A Review. Nutrients. 2019; 11 (8):1857.
Chicago/Turabian StyleIsabel Lorenzo; Mateu Serra-Prat; Juan Carlos Yébenes. 2019. "The Role of Water Homeostasis in Muscle Function and Frailty: A Review." Nutrients 11, no. 8: 1857.
Critically ill patients often require life support measures such as mechanical ventilation or haemodialysis. Despite the essential role of nutrition in patients’ recovery, the inappropriate use of medical nutrition therapy can have deleterious effects, as is the case with the use of respiratory, circulatory, or renal support. To increase awareness and to monitor the effects of inappropriate medical nutrition therapy, we propose to introduce the concept of nutritrauma in clinical practice, defined as metabolic adverse events related to the inappropriate administration of medical nutrition therapy or inadequate nutritional monitoring.
Juan Carlos Yébenes; Lluis Campins; Itziar Martínez De Lagran; Lluisa Bordeje; Carol Lorencio; Teodoro Grau; Juan Carlos Montejo; Maria Bodí; Mateu Serra-Prat; Working Group on Nutrition and Metabolism of the Spanish Society of Critical Care. Nutritrauma: A Key Concept for Minimising the Harmful Effects of the Administration of Medical Nutrition Therapy. Nutrients 2019, 11, 1775 .
AMA StyleJuan Carlos Yébenes, Lluis Campins, Itziar Martínez De Lagran, Lluisa Bordeje, Carol Lorencio, Teodoro Grau, Juan Carlos Montejo, Maria Bodí, Mateu Serra-Prat, Working Group on Nutrition and Metabolism of the Spanish Society of Critical Care. Nutritrauma: A Key Concept for Minimising the Harmful Effects of the Administration of Medical Nutrition Therapy. Nutrients. 2019; 11 (8):1775.
Chicago/Turabian StyleJuan Carlos Yébenes; Lluis Campins; Itziar Martínez De Lagran; Lluisa Bordeje; Carol Lorencio; Teodoro Grau; Juan Carlos Montejo; Maria Bodí; Mateu Serra-Prat; Working Group on Nutrition and Metabolism of the Spanish Society of Critical Care. 2019. "Nutritrauma: A Key Concept for Minimising the Harmful Effects of the Administration of Medical Nutrition Therapy." Nutrients 11, no. 8: 1775.
Community-acquired pneumonia (CAP) is a frequent cause of death worldwide. As recently described, CAP shows different biological endotypes. Improving characterization of these endotypes is needed to optimize individualized treatment of this disease. The potential value of the leukogram to assist prognosis in severe CAP has not been previously addressed. A cohort of 710 patients with CAP admitted to the intensive care units (ICUs) at Hospital of Mataró and Parc Taulí Hospital of Sabadell was retrospectively analyzed. Patients were split in those with septic shock (n = 304) and those with no septic shock (n = 406). A single blood sample was drawn from all the patients at the time of admission to the emergency room. ICU mortality was the main outcome. Multivariate analysis demonstrated that lymphopenia <675 cells/mm3 or <501 cells/mm3 translated into 2.32- and 3.76-fold risk of mortality in patients with or without septic shock, respectively. In turn, neutrophil counts were associated with prognosis just in the group of patients with septic shock, where neutrophils <8850 cells/mm3 translated into 3.6-fold risk of mortality. lymphopenia is a preserved risk factor for mortality across the different clinical presentations of severe CAP (sCAP), while failing to expand circulating neutrophils counts beyond the upper limit of normality represents an incremental immunological failure observed just in those patients with the most severe form of CAP, septic shock.
Estel Güell; Marta Martín-Fernandez; Mari C. De La Torre; Elisabet Palomera; Mateu Serra; Rafael Martinez; Manel Solsona; Gloria Miró; Jordi Vallès; Samuel Fernández; Edgar Cortés; Vanessa Ferrer; Marc Morales; Juan C. Yébenes; Jordi Almirall; Jesús F. Bermejo-Martin. Impact of Lymphocyte and Neutrophil Counts on Mortality Risk in Severe Community-Acquired Pneumonia with or without Septic Shock. Journal of Clinical Medicine 2019, 8, 754 .
AMA StyleEstel Güell, Marta Martín-Fernandez, Mari C. De La Torre, Elisabet Palomera, Mateu Serra, Rafael Martinez, Manel Solsona, Gloria Miró, Jordi Vallès, Samuel Fernández, Edgar Cortés, Vanessa Ferrer, Marc Morales, Juan C. Yébenes, Jordi Almirall, Jesús F. Bermejo-Martin. Impact of Lymphocyte and Neutrophil Counts on Mortality Risk in Severe Community-Acquired Pneumonia with or without Septic Shock. Journal of Clinical Medicine. 2019; 8 (5):754.
Chicago/Turabian StyleEstel Güell; Marta Martín-Fernandez; Mari C. De La Torre; Elisabet Palomera; Mateu Serra; Rafael Martinez; Manel Solsona; Gloria Miró; Jordi Vallès; Samuel Fernández; Edgar Cortés; Vanessa Ferrer; Marc Morales; Juan C. Yébenes; Jordi Almirall; Jesús F. Bermejo-Martin. 2019. "Impact of Lymphocyte and Neutrophil Counts on Mortality Risk in Severe Community-Acquired Pneumonia with or without Septic Shock." Journal of Clinical Medicine 8, no. 5: 754.
High intracellular water (ICW) content has been associated with better functional performance and a lower frailty risk in elderly people. However, it is not clear if the protective effect of high ICW is due to greater muscle mass or better muscle quality and cell hydration. We aimed to assess the relationship between ICW content in lean mass (LM) and muscle strength, functional performance, frailty, and other clinical characteristics in elderly people. In an observational cross-sectional study of community-dwelling subjects aged ≥75 years, ICW and LM were estimated by bioelectrical impedance, and the ICW/LM ratio (mL/kg) calculated. Muscle strength was measured as hand grip, frailty status was assessed according to Fried criteria, and functional status was assessed by Barthel score. For 324 recruited subjects (mean age 80 years), mean (SD) ICW/LM ratio was 408 (29.3) mL/kg. The ICW/LM ratio was negatively correlated with age (rs = −0.249; p < 0.001). A higher ICW/LM ratio was associated with greater muscle strength, better functional capacity, and a lower frailty risk, even when adjusted by age, sex, nº of co-morbidities, and LM. ICW content in LM (including the muscle) may influence muscle strength, functional capacity and frailty. However, further studies are needed to confirm this hypothesis.
Mateu Serra-Prat; Isabel Lorenzo; Elisabet Palomera; Juan Carlos Yébenes; Lluís Campins; Mateu Cabré. Intracellular Water Content in Lean Mass is Associated with Muscle Strength, Functional Capacity, and Frailty in Community-Dwelling Elderly Individuals. A Cross-Sectional Study. Nutrients 2019, 11, 661 .
AMA StyleMateu Serra-Prat, Isabel Lorenzo, Elisabet Palomera, Juan Carlos Yébenes, Lluís Campins, Mateu Cabré. Intracellular Water Content in Lean Mass is Associated with Muscle Strength, Functional Capacity, and Frailty in Community-Dwelling Elderly Individuals. A Cross-Sectional Study. Nutrients. 2019; 11 (3):661.
Chicago/Turabian StyleMateu Serra-Prat; Isabel Lorenzo; Elisabet Palomera; Juan Carlos Yébenes; Lluís Campins; Mateu Cabré. 2019. "Intracellular Water Content in Lean Mass is Associated with Muscle Strength, Functional Capacity, and Frailty in Community-Dwelling Elderly Individuals. A Cross-Sectional Study." Nutrients 11, no. 3: 661.
Montserrat Méndez-Brich; Mateu Serra-Prat; Elisabet Palomera; Esther Vendrell; Nicolás Morón; Ramón Boixeda; Mateu Cabré; Jordi Almirall. Social Determinants of Community-acquired Pneumonia: Differences by Age Groups. Archivos de Bronconeumología 2019, 55, 447 -449.
AMA StyleMontserrat Méndez-Brich, Mateu Serra-Prat, Elisabet Palomera, Esther Vendrell, Nicolás Morón, Ramón Boixeda, Mateu Cabré, Jordi Almirall. Social Determinants of Community-acquired Pneumonia: Differences by Age Groups. Archivos de Bronconeumología. 2019; 55 (8):447-449.
Chicago/Turabian StyleMontserrat Méndez-Brich; Mateu Serra-Prat; Elisabet Palomera; Esther Vendrell; Nicolás Morón; Ramón Boixeda; Mateu Cabré; Jordi Almirall. 2019. "Social Determinants of Community-acquired Pneumonia: Differences by Age Groups." Archivos de Bronconeumología 55, no. 8: 447-449.
Tatiana Rejón; Mateu Serra-Prat; Emili Burdoy; Mateu Cabré. Diferencias de género en los factores de riesgo de caídas en las personas mayores. Revista Española de Geriatría y Gerontología 2019, 54, 238 -240.
AMA StyleTatiana Rejón, Mateu Serra-Prat, Emili Burdoy, Mateu Cabré. Diferencias de género en los factores de riesgo de caídas en las personas mayores. Revista Española de Geriatría y Gerontología. 2019; 54 (4):238-240.
Chicago/Turabian StyleTatiana Rejón; Mateu Serra-Prat; Emili Burdoy; Mateu Cabré. 2019. "Diferencias de género en los factores de riesgo de caídas en las personas mayores." Revista Española de Geriatría y Gerontología 54, no. 4: 238-240.
Evaluar si el conocimiento de la enfermedad asmática puede ser un factor protector frente al riesgo de neumonía adquirida en la comunidad (NAC) en las personas con asma mayores de 18 años que reciben tratamiento inhalado. Estudio observacional de casos y controles en población con asma. Se reclutaron 123 personas con asma diagnosticadas de neumonía por criterios clínicos y radiológicos (casos) y 246 personas con asma no diagnosticados de neumonía durante el último año (controles), apareados por edad. El principal factor de estudio fue la valoración del conocimiento sobre la enfermedad asmática mediante un cuestionario ad hoc, de 7 preguntas con 2 posibles respuestas (conoce, no conoce). El análisis bivariado muestra que el conocimiento de la enfermedad asmática tiene una asociación estadísticamente significativa como factor protector de NAC. En el análisis multivariante muestra una asociación del conocimiento de la enfermedad asmática como factor protector de NAC (OR = 0,24), independientemente de la edad, nivel de estudios, funcionalidad y gravedad del asma. Un buen conocimiento de la enfermedad asmática permite reducir el riesgo de NAC en pacientes asmáticos con tratamiento inhalado. To assess whether knowledge of asthmatic disease may be a protective factor against the risk of community-acquired pneumonia (CAP) in people with asthma over the age of 18 who receive inhaled treatment. observational study of cases and controls in a population with asthma. One hundred and twenty-three people with asthma diagnosed with pneumonia were recruited according to clinical and radiological criteria (cases), and 246 people with asthma not diagnosed with pneumonia during the past year (controls), matched by age. The main study factor was the assessment of knowledge about asthmatic disease through an ad hoc questionnaire, with seven questions and two possible answers (known, unknown). the bivariate analysis shows that knowledge of asthmatic disease has a statistically significant association as a protective factor of CAP. In the multivariate analysis, it shows an association of knowledge of asthmatic disease as a protective factor of CAP (OR = .24), regardless of age, level of studies, functionality, and severity of asthma. A good knowledge of asthmatic disease reduces the risk of CAP in asthmatic patients using inhaled treatment.
Francesc Rodríguez; Analía Duran; Zulema Muñoz; Mateu Serra-Prat; Ramón Boixeda; María Carmen Ruiz. Conocimiento de la enfermedad asmática como factor protector de neumonía. Enfermería Clínica 2018, 30, 108 -113.
AMA StyleFrancesc Rodríguez, Analía Duran, Zulema Muñoz, Mateu Serra-Prat, Ramón Boixeda, María Carmen Ruiz. Conocimiento de la enfermedad asmática como factor protector de neumonía. Enfermería Clínica. 2018; 30 (2):108-113.
Chicago/Turabian StyleFrancesc Rodríguez; Analía Duran; Zulema Muñoz; Mateu Serra-Prat; Ramón Boixeda; María Carmen Ruiz. 2018. "Conocimiento de la enfermedad asmática como factor protector de neumonía." Enfermería Clínica 30, no. 2: 108-113.
IntroductionOropharyngeal dysphagia (OD) is a major disorder following stroke. OD can produce alterations in both the efficacy and safety of deglutition and may result in malnutrition, dehydration, frailty, respiratory infections and pneumonia. These complications can be avoided by early detection and treatment of OD in poststroke patients, and hospital stays, medication and mortality rates can be reduced. In addition to acute in-hospital costs from OD complications, there are other costs related to poststroke OD such as direct non-healthcare costs or indirect costs. The objective of this systematic review is to assess and summarise literature on the costs related to OD in poststroke patients.Methods and analysisA systematic review of studies on the cost of OD and its complications (aspiration, malnutrition, dehydration, aspiration pneumonia and death) in patients who had a stroke will be performed from the perspectives of the hospital, the healthcare system and/or the society. The main outcomes of interest are the costs related to poststroke OD. We will search MEDLINE, Embase and the National Health Service Economic Evaluation Database. Studies will be included if they are partial economic evaluation studies, studies that provide information on costs in adult (>17 years) poststroke patients with OD and/or its complications (malnutrition, dehydration, frailty, respiratory infections and pneumonia) or economic evaluation studies in which the cost of this condition has been estimated. Studies will be excluded if they refer to oesophageal dysphagia or OD caused by causes other than stroke. Main study information will be presented and summarised in tables, separately for studies that provide incremental costs attributable to OD or its complications and studies that report the effect of OD or its complications on total costs of stroke, and according to the perspective from which costs were measured.Ethics and disseminationThe results of this systematic review will be published in a peer-reviewed journal.PROSPERO registration numberCRD42018099977.
Sergio Marin; Mateu Serra-Prat; Omar Ortega; Pere Clavé. Cost of oropharyngeal dysphagia after stroke: protocol for a systematic review. BMJ Open 2018, 8, e022775 .
AMA StyleSergio Marin, Mateu Serra-Prat, Omar Ortega, Pere Clavé. Cost of oropharyngeal dysphagia after stroke: protocol for a systematic review. BMJ Open. 2018; 8 (12):e022775.
Chicago/Turabian StyleSergio Marin; Mateu Serra-Prat; Omar Ortega; Pere Clavé. 2018. "Cost of oropharyngeal dysphagia after stroke: protocol for a systematic review." BMJ Open 8, no. 12: e022775.
To assess the clinical characteristics of patients with Charcot neuroarthropathy (CN) in Spain and to identify predictors for CN-related complications. A retrospective study was conducted at five tertiary hospitals with diabetic foot care units in Spain. Data were collected from 83 patients, including demographic profiles, foot factors, diabetes characteristics, and presence of microvascular and macrovascular comorbidity, and a podiatric examination was also performed. Logistic regression analyses were used to determine significant predictors of the predefined clinical events. Signs of diabetic neuropathy were found in almost all patients (98.9%) at the initial assessment, approximately half of them had diabetic retinopathy or nephropathy (61.5% and 51.8%, respectively), and peripheral artery disease was uncommon (8.6%). Thirty-eight patients (47.5%) experienced one or more relevant clinical events: 22 (27.5%) a new foot ulcer; 7 (8.7%) a major amputation; 20 (25%) were admitted to hospital; and 4 (5%) died. Only the presence of diabetic nephropathy was independently associated to development of any of the complications studied (p = 0.009; odds ratio = 3.37; 95% CI: 1.12-10.1). Almost half the patients with CN attending specialised foot care units in tertiary hospitals experienced short-term CN-associated complications, and the risk was 3 times higher in those with a history of diabetic nephropathy. Determinar las características clínicas de pacientes con neuroartropatía de Charcot (NC) en España e identificar predictores de complicaciones relacionadas. Estudio retrospectivo llevado a cabo en 5 hospitales terciarios de España con unidad de pie diabético. Se recopilaron datos de 83 pacientes incluyendo perfil demográfico, datos provenientes de la exploración podológica, características de la diabetes y presencia de comorbilidad micro y macro vascular. Para determinar los predictores significativos de acontecimientos clínicos predefinidos se utilizaron análisis de regresión logística. Casi todos los pacientes (98,9%) tenían signos de neuropatía diabética en la evaluación inicial, aproximadamente la mitad tenían retinopatía o nefropatía diabética (61,5 y 51,8%, respectivamente) y la enfermedad arterial periférica era infrecuente (8,6%). Treinta y ocho pacientes (47,5%) experimentaron uno o más acontecimientos clínicos relevantes: 22 (27,5%) una nueva úlcera en el pie, 7 (8,7%) una amputación mayor, 20 (25%) fueron hospitalizados y 4 (5%) murieron. Solamente la presencia de nefropatía diabética se encontró independientemente asociada al desarrollo de alguna de las complicaciones estudiadas (p = 0,009; odds ratio = 3,37; 95% CI: 1,12-10,1). Casi la mitad de los pacientes con NC atendidos en unidades de cuidado del pie diabético en hospitales terciarios experimentaron complicaciones asociadas a NC a corto plazo, y el riesgo entre aquellos sujetos con historia de úlcera previa era 3 veces mayor.
Montserrat Doria; Jordi Viadé; Elisabet Palomera; Ricard Pérez; Melcior Lladó; Elisabet Costa; Teresa Huguet; Jordi Lluís Reverter; Mateu Serra-Prat; Josep Franch-Nadal; Dídac Mauricio. Short-term foot complications in Charcot neuroarthropathy: A retrospective study in tertiary care centres in Spain. Endocrinología, Diabetes y Nutrición (English ed.) 2018, 65, 479 -485.
AMA StyleMontserrat Doria, Jordi Viadé, Elisabet Palomera, Ricard Pérez, Melcior Lladó, Elisabet Costa, Teresa Huguet, Jordi Lluís Reverter, Mateu Serra-Prat, Josep Franch-Nadal, Dídac Mauricio. Short-term foot complications in Charcot neuroarthropathy: A retrospective study in tertiary care centres in Spain. Endocrinología, Diabetes y Nutrición (English ed.). 2018; 65 (9):479-485.
Chicago/Turabian StyleMontserrat Doria; Jordi Viadé; Elisabet Palomera; Ricard Pérez; Melcior Lladó; Elisabet Costa; Teresa Huguet; Jordi Lluís Reverter; Mateu Serra-Prat; Josep Franch-Nadal; Dídac Mauricio. 2018. "Short-term foot complications in Charcot neuroarthropathy: A retrospective study in tertiary care centres in Spain." Endocrinología, Diabetes y Nutrición (English ed.) 65, no. 9: 479-485.
As a person ages, total body water (TBW), intracellular water (ICW), muscle mass and muscle strength tend to decline. The decline in ICW may reflect losses in the number of muscle cells but may also be responsible for less hydrated muscle cells. To assess whether TBW and ICW are associated with muscle strength, functional performance and frailty in an aged population, independently of muscle mass. Methodology An observational cross-sectional study of community-dwelling individuals aged 75 years and older. TBW, ICW, fat mass, lean mass and muscle mass were assessed by bioelectrical impedance analysis, frailty status was measured according to Fried criteria, handgrip strength was measured using the hand-held JAMAR dynamometer, and functional performance was measured according to the Barthel index and gait speed. A total of 324 subjects were recruited (mean age 80.1 years, 47.5% women). TBW and ICW were closely correlated with muscle mass in both sexes. ICW was also associated with Barthel score, gait speed and frailty in both sexes and with handgrip in men. Considerable variability in ICW was observed for the same muscle mass. Multivariate analysis showed a positive effect of ICW on handgrip, functional performance and gait speed and a protective effect of ICW on frailty, independently of age, sex, body mass index and number of comorbidities. In elderly individuals with similar muscle mass, those with higher ICW had a better functional performance and a lower frailty risk, suggesting a protective effect of cell hydration, independently of muscle mass.
Mateu Serra-Prat; I. Lorenzo; E. Palomera; S. Ramírez; J. C. Yébenes. Total Body Water and Intracellular Water Relationships with Muscle Strength, Frailty and Functional Performance in an Elderly Population. A Cross-Sectional Study. The journal of nutrition, health & aging 2018, 23, 96 -101.
AMA StyleMateu Serra-Prat, I. Lorenzo, E. Palomera, S. Ramírez, J. C. Yébenes. Total Body Water and Intracellular Water Relationships with Muscle Strength, Frailty and Functional Performance in an Elderly Population. A Cross-Sectional Study. The journal of nutrition, health & aging. 2018; 23 (1):96-101.
Chicago/Turabian StyleMateu Serra-Prat; I. Lorenzo; E. Palomera; S. Ramírez; J. C. Yébenes. 2018. "Total Body Water and Intracellular Water Relationships with Muscle Strength, Frailty and Functional Performance in an Elderly Population. A Cross-Sectional Study." The journal of nutrition, health & aging 23, no. 1: 96-101.
Background: A change in healthcare systems is needed, due to the increased prevalence of chronic diseases. Patient empowerment improves results in terms of patient quality of life (QoL) and satisfaction. Introduction: We have developed a telehealth program Control Telehealth Claudication Intermittent (CONTECI) for patients with peripheral arterial disease (PAD), aimed at enhancing patient satisfaction and QoL, while improving health system efficiency. Materials and Methods: We conducted a randomized clinical trial of patients with PAD, at the intermittent claudication stage. Study subjects were randomized into either (1) an intervention arm (IA), which utilized our CONTECI program for promoting patient self-management, or (2) a control arm (CA), utilizing the familiar system of in-person patient visits. All patients were followed up at 1 year. Results: The trial included 150 patients, 75 in each arm. Complications were diagnosed more quickly in the IA (7.85 days standard deviation (SD) 9.95 vs. 53.89 days SD 41.56; p = 0.016) compared with the CA. Rest pain decreased (1.4% vs. 8.4%; p = 0.05) in the IA group, as did the number of scheduled visits—decreased by 95.95%—and the number of emergency visits (p = 0.017). QoL scores in IA patients improved from baseline (67.87 vs. 72.25; p = 0.047), as did patient satisfaction (67.36 vs. 76.78; p = 0.03). Discussion: Telemedicine can improve health results and aid communication and visit scheduling. Our e-Health programs are financially viable. Conclusions: Self-management using the CONTECI telehealth program is feasible for patients with PAD. The program promotes patient expertise, encourages proactivity, increases QoL and satisfaction with disease control, and improves health resource use, with no evidence of clinical inferiority to conventional practices.
Meritxell Davins Riu; Xavier Borràs Pérez; Vicenç Artigas Raventós; Elisabet Palomera Fanegas; Mateu Serra Prat; Jesus Alós Villacrosa. Use of Telehealth as a New Model for Following Intermittent Claudication and Promoting Patient Expertise. Telemedicine and e-Health 2018, 24, 773 -781.
AMA StyleMeritxell Davins Riu, Xavier Borràs Pérez, Vicenç Artigas Raventós, Elisabet Palomera Fanegas, Mateu Serra Prat, Jesus Alós Villacrosa. Use of Telehealth as a New Model for Following Intermittent Claudication and Promoting Patient Expertise. Telemedicine and e-Health. 2018; 24 (10):773-781.
Chicago/Turabian StyleMeritxell Davins Riu; Xavier Borràs Pérez; Vicenç Artigas Raventós; Elisabet Palomera Fanegas; Mateu Serra Prat; Jesus Alós Villacrosa. 2018. "Use of Telehealth as a New Model for Following Intermittent Claudication and Promoting Patient Expertise." Telemedicine and e-Health 24, no. 10: 773-781.
To assess the clinical characteristics of patients with Charcot neuroarthropathy (CN) in Spain and to identify predictors for CN-related complications. A retrospective study was conducted at five tertiary hospitals with diabetic foot care units in Spain. Data were collected from 83 patients, including demographic profiles, foot factors, diabetes characteristics, and presence of microvascular and macrovascular comorbidity, and a podiatric examination was also performed. Logistic regression analyses were used to determine significant predictors of the predefined clinical events. Signs of diabetic neuropathy were found in almost all patients (98.9%) at the initial assessment, approximately half of them had diabetic retinopathy or nephropathy (61.5% and 51.8%, respectively), and peripheral artery disease was uncommon (8.6%). Thirty-eight patients (47.5%) experienced one or more relevant clinical events: 22 (27.5%) a new foot ulcer; 7 (8.7%) a major amputation; 20 (25%) were admitted to hospital; and 4 (5%) died. Only the presence of diabetic nephropathy was independently associated to development of any of the complications studied (p = 0.009; odds ratio = 3.37; 95% CI: 1.12-10.1). Almost half the patients with CN attending specialised foot care units in tertiary hospitals experienced short-term CN-associated complications, and the risk was 3 times higher in those with a history of diabetic nephropathy. Determinar las características clínicas de pacientes con neuroartropatía de Charcot (NC) en España e identificar predictores de complicaciones relacionadas. Estudio retrospectivo llevado a cabo en 5 hospitales terciarios de España con unidad de pie diabético. Se recopilaron datos de 83 pacientes incluyendo perfil demográfico, datos provenientes de la exploración podológica, características de la diabetes y presencia de comorbilidad micro y macro vascular. Para determinar los predictores significativos de acontecimientos clínicos predefinidos se utilizaron análisis de regresión logística. Casi todos los pacientes (98,9%) tenían signos de neuropatía diabética en la evaluación inicial, aproximadamente la mitad tenían retinopatía o nefropatía diabética (61,5 y 51,8%, respectivamente) y la enfermedad arterial periférica era infrecuente (8,6%). Treinta y ocho pacientes (47,5%) experimentaron uno o más acontecimientos clínicos relevantes: 22 (27,5%) una nueva úlcera en el pie, 7 (8,7%) una amputación mayor, 20 (25%) fueron hospitalizados y 4 (5%) murieron. Solamente la presencia de nefropatía diabética se encontró independientemente asociada al desarrollo de alguna de las complicaciones estudiadas (p = 0,009; odds ratio = 3,37; 95% CI: 1,12-10,1). Casi la mitad de los pacientes con NC atendidos en unidades de cuidado del pie diabético en hospitales terciarios experimentaron complicaciones asociadas a NC a corto plazo, y el riesgo entre aquellos sujetos con historia de úlcera previa era 3 veces mayor.
Montserrat Doria; Jordi Viadé; Elisabet Palomera; Ricard Pérez; Melcior Lladó; Elisabet Costa; Teresa Huguet; Jordi Lluís Reverter; Mateu Serra-Prat; Josep Franch-Nadal; Dídac Mauricio. Short-term foot complications in Charcot neuroarthropathy: A retrospective study in tertiary care centres in Spain. Endocrinología, Diabetes y Nutrición 2018, 65, 479 -485.
AMA StyleMontserrat Doria, Jordi Viadé, Elisabet Palomera, Ricard Pérez, Melcior Lladó, Elisabet Costa, Teresa Huguet, Jordi Lluís Reverter, Mateu Serra-Prat, Josep Franch-Nadal, Dídac Mauricio. Short-term foot complications in Charcot neuroarthropathy: A retrospective study in tertiary care centres in Spain. Endocrinología, Diabetes y Nutrición. 2018; 65 (9):479-485.
Chicago/Turabian StyleMontserrat Doria; Jordi Viadé; Elisabet Palomera; Ricard Pérez; Melcior Lladó; Elisabet Costa; Teresa Huguet; Jordi Lluís Reverter; Mateu Serra-Prat; Josep Franch-Nadal; Dídac Mauricio. 2018. "Short-term foot complications in Charcot neuroarthropathy: A retrospective study in tertiary care centres in Spain." Endocrinología, Diabetes y Nutrición 65, no. 9: 479-485.
Francesc Rodríguez; Analía Duran; Zulema Muñoz; Elisabet Palomera; Mateu Serra-Prat; Ramón Boixeda; Vanesa Vicente; Jordi Almirall. Salud bucodental y riesgo de neumonía en pacientes asmáticos con tratamiento inhalado. Medicina Clínica 2018, 150, 455 -459.
AMA StyleFrancesc Rodríguez, Analía Duran, Zulema Muñoz, Elisabet Palomera, Mateu Serra-Prat, Ramón Boixeda, Vanesa Vicente, Jordi Almirall. Salud bucodental y riesgo de neumonía en pacientes asmáticos con tratamiento inhalado. Medicina Clínica. 2018; 150 (12):455-459.
Chicago/Turabian StyleFrancesc Rodríguez; Analía Duran; Zulema Muñoz; Elisabet Palomera; Mateu Serra-Prat; Ramón Boixeda; Vanesa Vicente; Jordi Almirall. 2018. "Salud bucodental y riesgo de neumonía en pacientes asmáticos con tratamiento inhalado." Medicina Clínica 150, no. 12: 455-459.