The increase in stroke incidence with the aging of the Korean population will rapidly impose an economic burden on society. Timely treatment can improve stroke prognosis. Awareness of stroke warning signs and appropriate actions in the event of a stroke improve outcomes. Medical service use and health behavior data are easier to collect than medical imaging data. Here, we used a deep neural network to detect stroke using medical service use and health behavior data; we identified 15,099 patients with stroke. Principal component analysis (PCA) featuring quantile scaling was used to extract relevant background features from medical records; we used these to predict stroke. We compared our method (a scaled PCA/deep neural network [DNN] approach) to five other machine-learning methods. The area under the curve (AUC) value of our method was 83.48%; hence; it can be used by both patients and doctors to prescreen for possible stroke.

A large number of people suffer from certain types of osteoarthritis, such as knee, hip, and spine osteoarthritis. A correct prediction of osteoarthritis is an essential step to effectively diagnose and prevent severe osteoarthritis. Osteoarthritis is commonly diagnosed by experts through manual inspection of patients’ medical images, which are usually collected in hospitals. Checking the occurrence of osteoarthritis is somewhat time-consuming for patients. In addition, the current studies are focused on automatically detecting osteoarthritis through image-based deep learning algorithms. This needs patients’ medical images, which requires patients to visit the hospital. However, medical utilization and health behavior information as statistical data are easier to collect and access than medical images. Using indirect statistical data without any medical images to predict the occurrence of diverse forms of OA can have significant impacts on pro-active and preventive medical care. In this study, we used a deep neural network for detecting the occurrence of osteoarthritis using patient’s statistical data of medical utilization and health behavior information. The study was based on 5749 subjects. Principal component analysis with quantile transformer scaling was employed to generate features from the patients’ simple background medical records and identify the occurrence of osteoarthritis. Our experiments showed that the proposed method using deep neural network with scaled PCA resulted in 76.8% of area under the curve (AUC) and minimized the effort to generate features. Hence, this methos can be a promising tool for patients and doctors to prescreen for possible osteoarthritis to reduce health costs and patients’ time in hospitals.

Many previous studies have identified that physiological responses of a driver are significantly associated with driving stress. However, research is limited to identifying the effects of traffic conditions (low vs. high traffic) and road types (highway vs. city) on driving stress. The objective of this study is to quantify the relationship between driving stress and traffic conditions, and driving stress and road types, respectively. In this study, electrodermal activity (EDA) signals for a male driver were collected in real road driving conditions for 60 min a day for 21 days. To classify the levels of driving stress (low vs. high), two separate models were developed by incorporating the statistical features of the EDA signals, one for traffic conditions and the other for road types. Both models were based on the application of EDA features with the logistic regression analysis. City driving turned out to be more stressful than highway driving. Traffic conditions, defined as traffic jam also significantly affected the stress level of the driver, when using the criteria of the vehicle speed of 40 km/h and standard deviation of the speed of 20 km/h. Relevance to industry: The classification results of the two models indicate that the traffic conditions and the road types are important features for driving stress and its related applications.

Mental health-related disorders are common in elderly populations. Among the various mental health disorders, one most significant threat is dementia, and prediction of dementia has become an important issue related to well-being in old age, because the disease progression of dementia can be slowed by early diagnosis and disease control. In this paper, we propose an unobtrusive dementia-prediction system for monitoring physical activities of elderly persons either living alone or as a couple in different house structures, achieved through passive infrared (PIR) motion sensors combined with data processing. The proposed feature extraction algorithm extracts feature values related to physical activities from simple passive infrared sensors located in each room space. We then apply a variety of common popular classification models, including Deep Neural Networks (DNNs), to predict the risk of dementia in a sensor-enabled home. We implemented and validated algorithms on data collected for over a month from 18 participants who were engaged with a variety of living conditions. The proposed system was effective in predicting dementia risk, with up to an 0.99 area under the curve (AUC) using DNN with principal component analysis (PCA) and a quantile transformer scaler. In terms of the result based on leave-one-subject-out (LOSO) analysis, an accuracy of 63.38% was achieved using DNN with PCA and a standard scaler. The proposed methodology is non-invasive and cost-effective, and can be used for a variety of long-term monitoring and early symptom detection systems, helping caregivers provide optimal interventions to elderly individuals at risk for dementia.

Aging population is a worldwide trend, which has created a societal crisis as many countries face the challenges of supporting an aging population with increasing costs of healthcare and decreasing numbers of caregivers. Sleep related disorders are common diseases, especially among the elderly. In this paper, we propose a simple and affordable unobtrusive sensing environment including a high-sensitive accelerometer on a bed and passive infrared (PIR) motion sensors in every room, following the generic framework of Internet of Health Things (IoHT) for monitoring the elderly’s sleep-wake conditions, to assess their sleep quality. The environment is nonintrusive, comfortable and can be used for long-term sleep monitoring, detecting early symptoms of sleep related disorders, and responding to caregivers. We implement and pilot test the environment under different daily living situations related to sleep quality. We develop a feature extraction algorithm and applied five popular data analytics models to assess their relative performance. Our study shows that all classifiers except Naïve Bayes can effectively detect sleep quality with the Area under ROC curve (AUC) performance higher than 90%. Among which multilayer feed-forward neural network achieved the best results, in which the detecting sensitivity is up to 96.61%, specificity is 91.81% and AUC performance is 94.21%.

Sleep apnea is a common sleep-related disorder that significantly affects the population. It is characterized by repeated breathing interruption during sleep. Such events can induce hypoxia, which is a risk factor for multiple cardiovascular and cerebrovascular diseases. Polysomnography, the gold standard, is expensive, inaccessible, uncomfortable and an expert technician is needed to score sleep-related events. To address these limitations, many previous studies have proposed and implemented automatic scoring processes based on fewer sensors and machine learning classification algorithms. However, alternative device technologies developed for both home and hospital still have limited diagnostic accuracy for detecting apnea events even though many of the previous investigational algorithms are based on multiple physiological channel inputs. In this paper, we propose a new probabilistic algorithm based on (only) oronasal respiration signal for automated detection of apnea events during sleep. The proposed model leverages AASM recommendations for characterizing apnea events with respect to dynamic changes in the local respiratory airflow baseline. Unlike classical threshold-based classification models, we use a Gaussian mixture probability model for detecting sleep apnea based on the posterior probabilities of the respective events. Our results show significant improvement in the ability to detect sleep apnea events compared to a rule-based classifier that uses the same classification features and also compared to two previously published studies for automated apnea detection using the same respiratory flow signal. We use 96 sleep patients with different apnea severity levels as reflected by their Apnea-Hypopnea Index (AHI) levels. The performance was not only analyzed over obstructive sleep apnea (OSA) but also over other types of sleep apnea events including central and mixed sleep apnea (CSA, MSA). Also the performance was comprehensively analyzed and evaluated over patients with varying disease severity conditions, where it achieved an overall performance of $TPR=88.5\%$, $TNR=82.5\%$, and $AUC=86.7\%$. The proposed approach contributes a new probabilistic framework for detecting sleep apnea events using a single airflow record with an improved capability to generalize over different apnea severity conditions