The presented review focuses on design strategies to develop tailor-made MOFs/CPs of main group, transition and inner-transition elements and their photocatalytic properties to decompose dyes in wastewater discharge and their photocatalytic mechanism.

Metal-organic frameworks (MOFs) show promising application in biomedicine and pharmaceutics owing to their extraordinarily high surface area, tunable pore size, and adjustable internal surface properties. However, MOFs are prepared from non-renewable or toxic materials, which limit their real-world applications. Cyclodextrins (CDs) are a typical natural and biodegradable cyclic oligosaccharide and are primarily used to enhance the aqueous solubility, safety, and bioavailability of drugs by virtue of its low toxicity and highly flexible structure, offering a peculiar ability to form CD/drug inclusions. A sophisticated strategy where CD is deployed as a ligand to form an assembly of cyclodextrin-based MOFs (CD-MOFs) may overcome real-world application drawbacks of MOFs. CD-MOFs incorporate the porous features of MOFs and the encapsulation capability of CD for drug molecules, leading to outstanding properties when compared with traditional hybrid materials. This review focuses on the inclusion technology and drug delivery properties associated with CD-MOFs. In addition, synthetic strategies and currently developed uses of CD-MOFs are highlighted as well. Also, perspectives and future challenges in this rapidly developing research area are discussed.

An overview on the recent progress in bimetallic MOFs regarding their design strategies, syntheses and multifarious applications.

Still today, cancer remains a threat to human health. Possible common treatments to cure this disease include chemotherapy (CT), radiotherapy (RT), photothermal therapy (PTT), and surgical resection, which give unreasonable results because of their limited efficiency and also lead to side-effects. Hence, different strategies are now being exploited to not only enhance the efficiency of these traditional therapeutic methods or treat the tumor cells but also curtail the side effects. A latest method with authentic proof of chemodynamic therapy (CDT) utilizing the Fenton reaction is now gaining importance. This approach, which is developed based on the high level of hydrogen peroxide (H₂O₂) in a tumor microenvironment (TME), can be used to catalyze the Fenton reaction to generate cancer cell-killing reactive oxygen species (ROS). The selection of materials is extremely important and nanomaterials offer the most likely method to facilitate CDT. Among various materials, metal–organic frameworks (MOFs) which have been extensively applied in medical areas are regarded as a promising material and possess potential for the next generation of nanotechnology. This review focuses on summarizing the use of MOFs in CDT and their synergetic therapeutics as well as the challenges, obstacles, and development.

In the present perspective, the use of MOFs in bone therapy and bone repair has been summarized, and an outlook on the future direction of MOFs in bone therapy and bone repair has been provided.

The incremental use of antibiotics is now posing a pollution problem in the aquatic system. Therefore, it is necessary to decompose this class of harmful components existing in wastewater. Metal–organic frameworks (MOFs) are a peculiar class of multidimensional materials that can be employed as a photocatalyst to decompose antibiotics present in the wastewater discharged. Herein, a stable Cd(II)-based metal–organic framework with the composition {[Cd₄(L)₂(dib)(H₂O)₃]·H₂O}_n (1), (H₄L = 3-(2,4-di-carboxyphenoxy)phthalic acid, dib = 1,4-bis(1-imidazolyl)benzene) has been synthesized hydrothermally and characterized. The single-crystal X-ray diffraction results indicate that 1 is a 3D 8-connected uninodal net with the point (3⁶·4¹⁸·5³·6). Further, 1 was employed as a catalyst for the oxidation of antibiotics viz. ornidazole (ODZ), nitrofural (NZF), and oxytetracycline (OXY) in an aqueous medium, amongst which the MOF exhibited the best photocatalytic decomposition performance against OXY. The plausible photocatalytic mechanism has been explained with the help of density of states calculations and Hirshfeld surface analysis.