This paper proposes a deep learning model based on an artificial neural network with a single hidden layer for predicting the diagnosis of multiple sclerosis. The hidden layer includes a regularization term that prevents overfitting and reduces the model complexity. The purposed learning model achieved higher prediction accuracy and lower loss than four conventional machine learning techniques. A dimensionality reduction method was used to select the most relevant features from 74 gene expression profiles for training the learning models. The analysis of variance test was performed to identify the statistical difference between the mean of the proposed model and the compared classifiers. The experimental results show the effectiveness of the proposed artificial neural network.

Crouch gait is one of the most common gait abnormalities; it is usually caused by cerebral palsy. There are few works related to the modeling of crouch gait kinematics, crouch gait analysis, and visualization in both the workspace and joint space. In this work, we present a quaternion-based method to solve the forward kinematics of the position of the lower limbs during walking. For this purpose, we propose a modified eight-DoF human skeletal model. Using this model, we present a geometric method to calculate the gait inverse kinematics. Both methods are applied for gait analysis over normal, mild, and severe crouch gaits, respectively. A metric-based comparison of workspace and joint space for the three gaits for a gait cycle is conducted. In addition, gait visualization is performed using Autodesk Maya for the three anatomical planes. The obtained results allow us to determine the capabilities of the proposed methods to assess the performance of crouch gaits, using a normal pattern as a reference. Both forward and inverse kinematic methods could ultimately be applied in rehabilitation settings for the diagnosis and treatment of diseases derived from crouch gaits or other types of gait abnormalities.

The objective of this research is to present a comparative analysis using various lengths of time windows (TW) during emotion recognition, employing machine learning techniques and the portable wireless sensing device EPOC+. In this study, entropy will be utilized as a feature to evaluate the performance of different classifier models across various TW lengths, based on a dataset of EEG signals extracted from individuals during emotional stimulation. Two types of analyses were conducted: between-subjects and within-subjects. Performance measures such as accuracy, area under the curve, and Cohen's Kappa coefficient were compared among five supervised classifier models: K-Nearest Neighbors (KNN), Support Vector Machine (SVM), Logistic Regression (LR), Random Forest (RF), and Decision Trees (DT). The results indicate that, in both analyses, all five models exhibit higher performance in TW ranging from 2 to 15 seconds, with the 10 seconds TW particularly standing out for between-subjects analysis and the 5-second TW for within-subjects; furthermore, TW exceeding 20 seconds are not recommended. These findings provide valuable guidance for selecting TW in EEG signal analysis when studying emotions.

There exist several methods aimed at human–robot physical interaction (HRpI) to provide physical therapy in patients. The use of haptics has become an option to display forces along a given path so as to it guides the physiotherapist protocol. Critical in this regard is the motion control for haptic guidance to convey the specifications of the clinical protocol. Given the inherent patient variability, a conclusive demand of these HRpI methods is the need to modify online its response with neither rejecting nor neglecting interaction forces but to process them as patient interaction. In this paper, considering the nonlinear dynamics of the robot interacting bilaterally with a patient, we propose a novel adaptive control to guarantee stable haptic guidance by processing the causality of patient interaction forces, despite unknown robot dynamics and uncertainties. The controller implements radial basis neural network with daughter RASP1 wavelets activation function to identify the coupled interaction dynamics. For an efficient online implementation, an output infinite impulse response filter prunes negligible signals and nodes to deal with overparametrization. This contributes to adapt online the feedback gains of a globally stable discrete PID regulator to yield stiffness control, so the user is guided within a perceptual force field. Effectiveness of the proposed method is verified in real-time bimanual human-in-the-loop experiments.

Crouch gait, also referred to as flexed knee gait, is an abnormal walking pattern, characterized by an excessive flexion of the knee, and sometimes also with anomalous flexion in the hip and/or the ankle, during the stance phase of gait. Due to the fact that the amount of clinical data related to crouch gait are scarce, it is difficult to find studies addressing this problem from a data-based perspective. Consequently, in this paper we propose a gait recognition strategy using synthetic data that have been obtained using a polynomial based-generator. Furthermore, though this study, we consider datasets that correspond to different levels of crouch gait severity. The classification of the elements of the datasets into the different levels of abnormality is achieved by using different algorithms like k-nearest neighbors (KNN) and Naive Bayes (NB), among others. On the other hand, to evaluate the classification performance we consider different metrics, including accuracy (Acc) and F measure (FM). The obtained results show that the proposed strategy is able to recognize crouch gait with an accuracy of more than 92%. Thus, it is our belief that this recognition strategy may be useful during the diagnosis phase of crouch gait disease. Finally, the crouch gait recognition approach introduced here may be extended to identify other gait abnormalities.