Emmanouil Pikoulis

Dr. Emmanouil Pikoulis

3rd Department of Surgery, “Attikon” University General Hospital, National and Kapodistrian, University of Athens (NKUA), 11527 Athens, Greece

Research Focus & Metrics

Academic Career Length

28Years (1999-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
30 March 2020 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
TPThe Wses Expert Panel
The Wses Expert Panel
ACand Federico Coccolini
and Federico Coccolini
RCRaul Coimbra
Raul Coimbra
COCarlos Ordonez
Carlos Ordonez
YKYoram Kluger
Yoram Kluger
Fausto CatenaFausto Catena
Fausto Catena
Liver injuries represent one of the most frequent life-threatening injuries in trauma patients. In determining the optimal management strategy, the anatomic injury, the hemodynamic status, and the associated injuries should be taken into consideration. Liver trauma approach may require non-operative or operative management with the intent to restore the homeostasis and the normal physiology. The management of liver trauma should be multidisciplinary including trauma surgeons, interventional radiologists, and emergency and ICU physicians. The aim of this paper is to present the World Society of Emergency Surgery (WSES) liver trauma management guidelines.

2 December 2019 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
NDNicola De'Angelis
Nicola De'Angelis
ACand Federico Coccolini
and Federico Coccolini
EMErnest Moore
Ernest Moore
YKYoram Kluger
Yoram Kluger
WBWalter L. Biffl
Walter L. Biffl
Fausto CatenaFausto Catena
Fausto Catena
Renal and urogenital injuries occur in approximately 10-20% of abdominal trauma in adults and children. Optimal management should take into consideration the anatomic injury, the hemodynamic status, and the associated injuries. The management of urogenital trauma aims to restore homeostasis and normal physiology especially in pediatric patients where non-operative management is considered the gold standard. As with all traumatic conditions, the management of urogenital trauma should be multidisciplinary including urologists, interventional radiologists, and trauma surgeons, as well as emergency and ICU physicians. The aim of this paper is to present the World Society of Emergency Surgery (WSES) and the American Association for the Surgery of Trauma (AAST) kidney and urogenital trauma management guidelines.

11 December 2019 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
NDNicola De'Angelis
Nicola De'Angelis
ACand Federico Coccolini
and Federico Coccolini
LKLeslie Kobayashi
Leslie Kobayashi
YKYoram Kluger
Yoram Kluger
EMErnest Moore
Ernest Moore
RCRaul Coimbra
Raul Coimbra
Duodeno-pancreatic and extrahepatic biliary tree injuries are rare in both adult and pediatric trauma patients, and due to their anatomical location, associated injuries are very common. Mortality is primarily related to associated injuries, but morbidity remains high even in isolated injuries. Optimal management of duodeno-bilio-pancreatic injuries is dictated primarily by hemodynamic stability, clinical presentation, and grade of injury. Endoscopic and percutaneous interventions have increased the ability to non-operatively manage these injuries. Late diagnosis and treatment are both associated to increased morbidity and mortality. Sequelae of late presentations of pancreatic injury and complications of severe pancreatic trauma are also increasingly addressed endoscopically and with interventional radiology procedures. However, for moderate and severe extrahepatic biliary and severe duodeno-pancreatic injuries, immediate operative intervention is preferred as associated injuries are frequent and commonly present with hemodynamic instability or peritonitis. The aim of this paper is to present the World Society of Emergency Surgery (WSES) and American Association for the Surgery of Trauma (AAST) duodenal, pancreatic, and extrahepatic biliary tree trauma management guidelines.

15 December 2021 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
MTMarina Tsoumpa
Marina Tsoumpa
AKAikaterini Kyttari
Aikaterini Kyttari
SMStamo Matiatou
Stamo Matiatou
MTMaria Tzoufi
Maria Tzoufi
PGPanagiota Griva
Panagiota Griva
Tatiana SidiropoulouTatiana Sidiropoulou
Tatiana Sidiropoulou
(1) Background: The Hypotension Prediction Index (HPI) is an algorithm that predicts hypotension, defined as mean arterial pressure (MAP) less than 65 mmHg for at least 1 min, based on arterial waveform features. We tested the hypothesis that the use of this index reduces the duration and severity of hypotension during noncardiac surgery. (2) Methods: We enrolled adults having moderate- or high-risk noncardiac surgery with invasive arterial pressure monitoring. Participating patients were randomized 1:1 to standard of care or hemodynamic management with HPI guidance with a goal directed hemodynamic treatment protocol. The trigger to initiate treatment (with fluids, vasopressors, or inotropes) was a value of HPI of 85 (range, 0–100) or higher in the intervention group. Primary outcome was the amount of hypotension, defined as time-weighted average (TWA) MAP less than 65 mmHg. Secondary outcomes were time spent in hypertension defined as MAP more than 100 mmHg for at least 1 min; medication and fluids administered and postoperative complications. (3) Results: We obtained data from 99 patients. The median (IQR) TWA of hypotension was 0.16 mmHg (IQR, 0.01–0.32 mmHg) in the intervention group versus 0.50 mmHg (IQR, 0.11–0.97 mmHg) in the control group, for a median difference of −0.28 (95% CI, −0.48 to −0.09 mmHg; p = 0.0003). We also observed an increase in hypertension in the intervention group as well as a higher weight-adjusted administration of phenylephrine in the intervention group. (4) Conclusions: In this single-center prospective study of patients undergoing elective noncardiac surgery, the use of this prediction model resulted in less intraoperative hypotension compared with standard care. An increase in the time spent in hypertension in the treatment group was also observed, probably as a result of overtreatment. This should provide an insight for refining the use of this prediction index in future studies to avoid excessive correction of blood pressure.

9 August 2021 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
ACand Federico Coccolini
and Federico Coccolini
MIMario Improta
Mario Improta
MSMassimo Sartelli
Massimo Sartelli
Huseyin Kemal RasaHuseyin Kemal Rasa
Huseyin Kemal Rasa
Robert G SawyerRobert G Sawyer
Robert G Sawyer
Fausto CatenaFausto Catena
Fausto Catena
Immunocompromised patients are a heterogeneous and diffuse category frequently presenting to the emergency department with acute surgical diseases. Diagnosis and treatment in immunocompromised patients are often complex and must be multidisciplinary. Misdiagnosis of an acute surgical disease may be followed by increased morbidity and mortality. Delayed diagnosis and treatment of surgical disease occur; these patients may seek medical assistance late because their symptoms are often ambiguous. Also, they develop unique surgical problems that do not affect the general population. Management of this population must be multidisciplinary.This paper presents the World Society of Emergency Surgery (WSES), Surgical Infection Society Europe (SIS-E), World Surgical Infection Society (WSIS), American Association for the Surgery of Trauma (AAST), and Global Alliance for Infection in Surgery (GAIS) joined guidelines about the management of acute abdomen in immunocompromised patients.

9 April 2020 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
ACand Federico Coccolini
and Federico Coccolini
Massimo SartelliMassimo Sartelli
Massimo Sartelli
YKYoram Kluger
Yoram Kluger
Emmanouil PikoulisEmmanouil Pikoulis
Emmanouil Pikoulis
EKEvika Karamagioli
Evika Karamagioli
Fausto CatenaFausto Catena
Fausto Catena
Since December 2019, the world is potentially facing one of the most difficult infectious situations of the last decades. COVID-19 epidemic warrants consideration as a mass casualty incident (MCI) of the highest nature. An optimal MCI/disaster management should consider all four phases of the so-called disaster cycle: mitigation, planning, response, and recovery. COVID-19 outbreak has demonstrated the worldwide unpreparedness to face a global MCI.This present paper thus represents a call for action to solicitate governments and the Global Community to actively start effective plans to promote and improve MCI management preparedness in general, and with an obvious current focus on COVID-19.