Marco Valussi

Marco Valussi


Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2017 in Molecules
Verified
Journal Article
Open access
PDF file
Javad Sharifi-RadJavad Sharifi-Rad
Javad Sharifi-Rad
Antoni SuredaAntoni Sureda
Antoni Sureda
Gian Carlo TenoreGian Carlo Tenore
Gian Carlo Tenore
Maria DagliaMaria Daglia
Maria Daglia
MSMehdi Sharifi-Rad
Mehdi Sharifi-Rad
Marcello IritiMarcello Iriti
Marcello Iriti
Essential oils are complex mixtures of hydrocarbons and their oxygenated derivatives arising from two different isoprenoid pathways. Essential oils are produced by glandular trichomes and other secretory structures, specialized secretory tissues mainly diffused onto the surface of plant organs, particularly flowers and leaves, thus exerting a pivotal ecological role in plant. In addition, essential oils have been used, since ancient times, in many different traditional healing systems all over the world, because of their biological activities. Many preclinical studies have documented antimicrobial, antioxidant, anti-inflammatory and anticancer activities of essential oils in a number of cell and animal models, also elucidating their mechanism of action and pharmacological targets, though the paucity of in human studies limits the potential of essential oils as effective and safe phytotherapeutic agents. More well-designed clinical trials are needed in order to ascertain the real efficacy and safety of these plant products.

7 April 2019 in Molecules
Verified
Journal Article
Open access
PDF file
BSBahare Salehi
Bahare Salehi
ZZZainul Amiruddin Zakaria
Zainul Amiruddin Zakaria
RGRabin Gyawali
Rabin Gyawali
Salam IbrahimSalam Ibrahim
Salam Ibrahim
JRJovana Rajkovic
Jovana Rajkovic
William N. SetzerWilliam N. Setzer
William N. Setzer
Piper species are aromatic plants used as spices in the kitchen, but their secondary metabolites have also shown biological effects on human health. These plants are rich in essential oils, which can be found in their fruits, seeds, leaves, branches, roots and stems. Some Piper species have simple chemical profiles, while others, such as Piper nigrum, Piper betle, and Piper auritum, contain very diverse suites of secondary metabolites. In traditional medicine, Piper species have been used worldwide to treat several diseases such as urological problems, skin, liver and stomach ailments, for wound healing, and as antipyretic and anti-inflammatory agents. In addition, Piper species could be used as natural antioxidants and antimicrobial agents in food preservation. The phytochemicals and essential oils of Piper species have shown strong antioxidant activity, in comparison with synthetic antioxidants, and demonstrated antibacterial and antifungal activities against human pathogens. Moreover, Piper species possess therapeutic and preventive potential against several chronic disorders. Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, and neuropharmacological activities of the extracts and extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro and in vivo studies, besides clinical studies. Habitats and cultivation of Piper species are also covered in this review. In this current work, available literature of chemical constituents of the essential oils Piper plants, their use in traditional medicine, their applications as a food preservative, their antiparasitic activities and other important biological activities are reviewed.

Michele AntonelliMichele Antonelli
Michele Antonelli
Davide DonelliDavide Donelli
Davide Donelli
GBGrazia Barbieri
Grazia Barbieri
MVMarco Valussi
Marco Valussi
VMValentina Maggini
Valentina Maggini
FFFabio Firenzuoli
Fabio Firenzuoli
The aim of this research work is to analyze the chemistry and diversity of forest VOCs (volatile organic compounds) and to outline their evidence-based effects on health. This research work was designed as a narrative overview of the scientific literature. Inhaling forest VOCs like limonene and pinene can result in useful antioxidant and anti-inflammatory effects on the airways, and the pharmacological activity of some terpenes absorbed through inhalation may be also beneficial to promote brain functions by decreasing mental fatigue, inducing relaxation, and improving cognitive performance and mood. The tree composition can markedly influence the concentration of specific VOCs in the forest air, which also exhibits cyclic diurnal variations. Moreover, beneficial psychological and physiological effects of visiting a forest cannot be solely attributed to VOC inhalation but are due to a global and integrated stimulation of the five senses, induced by all specific characteristics of the natural environment, with the visual component probably playing a fundamental role in the overall effect. Globally, these findings can have useful implications for individual wellbeing, public health, and landscape design. Further clinical and environmental studies are advised, since the majority of the existing evidence is derived from laboratory findings.

1 November 2018 in Molecules
Verified
Journal Article
Open access
PDF file
BSBahare Salehi
Bahare Salehi
MVMarco Valussi
Marco Valussi
MMMaria Flaviana Bezerra Morais-Braga
Maria Flaviana Bezerra Morais-Braga
JCJoara Nalyda Pereira Carneiro
Joara Nalyda Pereira Carneiro
ALAntonio Leal
Antonio Leal
Javad Sharifi-RadJavad Sharifi-Rad
Javad Sharifi-Rad
Tagetes (marigold) is native to America, and its cultivation currently extends to other countries in Africa, Asia, and Europe. Many species of this genus, such as T. minuta, T. erecta, T. patula, and T. tenuifolia, are cultivated as ornamental plants and studied for their medicinal properties on the basis of their use in folk medicine. Different parts of the Tagetes species are used as remedies to treat various health problems, including dental, stomach, intestinal, emotional, and nervous disorders, as well as muscular pain, across the world. Furthermore, these plants are studied in the field of agriculture for their fungicidal, bactericidal, and insecticidal activities. The phytochemical composition of the extracts of different Tagetes species parts are reported in this work. These compounds exhibit antioxidant, antiinflammatory, and enzyme inhibitory properties. Cultivation and the factors affecting the chemical composition of Tagetes species are also covered. In the current work, available literature on Tagetes species in traditional medicine, their application as a food preservative, and their antimicrobial activities are reviewed.

1 October 2018 in Trends in Food Science & Technology
Verified
Journal Article
Closed access
BSBahare Salehi
Bahare Salehi
MVMarco Valussi
Marco Valussi
AJArun Jugran
Arun Jugran
Miquel MartorellMiquel Martorell
Miquel Martorell
KRKarina Ester Ramírez-Alarcón
Karina Ester Ramírez-Alarcón
Javad Sharifi-RadJavad Sharifi-Rad
Javad Sharifi-Rad

19 October 2011 in International Journal of Food Sciences and Nutrition
Verified
Journal Article
Closed access
MVMarco Valussi
Marco Valussi
On analyzing the traditional societies' plant lore by treatment and plant categories, one cannot but notice the greater weight given to treatment of digestive disturbances and ailments compared to modern Western pharmacopoeias, and the blurred boundaries between medicines and foods, in contrast to the clear-cut distinction made in contemporary industrialized societies. Hence, there is an interest in exploring the issue of multifunctional food and traditional ingredients with digestive properties. In this paper, I examine the coevolutionary foundations for digestive activities, the problems and ambiguities that emerge in the analysis of traditional data, and the possible biological mechanisms underlying the actions of bitter, aromatic and pungent compounds. After these premises, this paper presents a short review of those plants with a significant body of research supporting the claims that they have a digestive action, with particular emphasis on clinical data. The plants that have a substantial body of data in support of their digestion-enhancing activities mainly belong to one of three groups: bitter, aromatic and pungent plants. Amongst the most important we can find ginger, peppermint, aniseed and fennel, citrus fruits, dandelion and artichoke, melissa and chamomile, but many more have a significant body of experimental data available.