Pavel Michalek

Prof. Pavel Michalek

General University Hospital in Prague, Czech Republic
+1
orcid

Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 December 2015 in BioMed Research International
Verified
Journal Article
Open access
PDF file
Pavel MichalekPavel Michalek
Pavel Michalek
WDWilliam Donaldson
William Donaldson
EVEliska Vobrubova
Eliska Vobrubova
MHMarek Hakl
Marek Hakl
Supraglottic airway devices are routinely used for airway maintenance in elective surgical procedures where aspiration is not a significant risk and also as rescue devices in difficult airway management. Some devices now have features mitigating risk of aspiration, such as drain tubes or compartments to manage regurgitated content. Despite this, the use of these device may be associated with various complications including aspiration. This review highlights the types and incidence of these complications. They include regurgitation and aspiration of gastric contents, compression of vascular structures, trauma, and nerve injury. The incidence of such complications is quite low, but as some carry with them a significant degree of morbidity the need to follow manufacturers’ advice is underlined. The incidence of gastric content aspiration associated with the devices is estimated to be as low as 0.02% with perioperative regurgitation being significantly higher but underreported. Other serious, but extremely rare, complications include pharyngeal rupture, pneumomediastinum, mediastinitis, or arytenoid dislocation. Mild short-lasting adverse effects of the devices have significantly higher incidence than serious complications and involve postoperative sore throat, dysphagia, pain on swallowing, or hoarseness. Devices may have deleterious effect on cervical mucosa or vasculature depending on their cuff volume and pressure.

1 May 2008 in Anesthesia & Analgesia
Verified
Journal Article
Closed access
Pavel MichalekPavel Michalek
Pavel Michalek
PHPhilip Hodgkinson
Philip Hodgkinson
WDWilliam Donaldson
William Donaldson
We describe successful fiberoptic-guided tracheal intubation through the novel supraglottic "I-gel" airway in two uncooperative adult patients with genetic syndromes, learning disability, and predicted difficult airway, scheduled for complex dental treatment under general anesthesia. The I-gel maintained the airway immediately after induction, allowing oxygenation and ventilation. Location of the laryngeal inlet was successful on the first attempt with a fiberscope, and the tracheal tube was inserted into the trachea over the endoscope without complication in both patients. This report suggests another option for management of predicted difficult airways.

26 January 2022 in Current Atherosclerosis Reports
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Journal Article
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Jan MalikJan Malik
Jan Malik
LNLudmila Nováková
Ludmila Nováková
VAValerianova A.
Valerianova A.
CEChytilova E.
Chytilova E.
LVLejsek V.
Lejsek V.
Pavel MichalekPavel Michalek
Pavel Michalek

1 January 2010 in Resuscitation
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Journal Article
Closed access
Pavel MichalekPavel Michalek
Pavel Michalek
WDW. Donaldson
W. Donaldson
CGC. Graham
C. Graham
JHJ.D. Hinds
J.D. Hinds

1 December 2004 in Journal of Vascular Surgery
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Journal Article
Closed access
PŠPetr Štádler
Petr Štádler
OBOtakar Bìlohlávek
Otakar Bìlohlávek
MŠMiroslav Špaček
Miroslav Špaček
Pavel MichalekPavel Michalek
Pavel Michalek

9 July 2007 in British Journal of Anaesthesia
Verified
Journal Article
Open access
PDF file
MHM. Hakl
M. Hakl
Pavel MichalekPavel Michalek
Pavel Michalek
PŠP. Ševčík
P. Ševčík
JPJ. Pavlíková
J. Pavlíková
MSM. Stern
M. Stern
The aim of this retrospective study was to compare the failure rates and the frequency of anaesthesia-related complications of two different methods of regional anaesthesia used for carotid endarterectomy—cervical epidural (CE) anaesthesia and cervical plexus block (CPB). The study included 1828 carotid endarterectomies performed in 1455 patients between 1996 and 2006. A combination of deep and superficial CPB was used for 1166 procedures, whereas in 662 cases surgery was performed under CE anaesthesia. The failure rate of CPB was 3% compared with 6.9% for CE anaesthesia (P < 0.0001). The reasons for failure of the anaesthetic techniques were (1) technical failure, (2) insufficient analgesia, (3) non-compliant patients, and (4) anaesthetic complications. The incidence of complications resulting from CE anaesthesia was significantly higher than with CPB; life-threatening complications—2% compared with 0.3% (P < 0.0001); other anaesthesia-related complications 5.7 vs 4.7%. Serious complications included inadvertant injection into the subarachnoid space or vertebral artery. The frequency of shunt insertion, perioperative stroke, and death from any cause was similar in both groups of patients. Both methods of regional anaesthesia are acceptable for carotid artery surgery. CPB is associated with a significantly lower frequency of anaesthesia-related complications and should therefore be considered the anaesthetic of choice. CE anaesthesia should not be performed except in extenuating circumstances such as variant anatomy or the requirement for more extensive surgery.