Arteriovenous fistula (AVF) is currently the hemodialysis access with the longest life expectations for the patients. However, even the AVF is at risk for many complications, especially the development of stenosis. The latter can not only lead to inadequate hemodialysis but also lead to AVF thrombosis. Duplex Doppler ultrasonography is a very precise method, in the hands of experienced professionals, for the diagnosis of AVF complications. In this review, we summarize the ultrasound diagnostic criteria of significant stenoses and their indication for procedural therapy.
The need to achieve the sustainability goals and to reduce the continuous exploitation of the limited urban areas increases requests for the regeneration of brownfields. The current study aims to review the state of brownfields in the Northern Czech Region and neighboring German (Saxony) and Polish (Silesian) Regions which share a common geological background and environmental problems. The peculiarities of the brownfield’s properties related to the term, classification, legislative framework, access to available data, degree of contamination, and remediation methods were the focus of this review. It was established that the state with brownfield identification and transformation is better in the Czech Republic, followed by Germany, with lower awareness in Poland. The relevant examples of successful brownfield revitalization and the importance of educational components were introduced. A prospective application of the phytotechnology with the second-generation crops for the remediation of brownfields was discussed. The utilization of Miscanthus spp. for marginal lands with low contamination can provide an economic return by having biomass converted into energy or bioproducts and the utilization of the accompanied waste as carbon-rich biochar which can indeed support phytoremediation, enhance plants’ growth and serve as a medium for carbon sequestration. The next steps in the research have to concentrate on comparison of the rehabilitation methods introduced for the targeted regions with the global approach in brownfield redevelopment along with the practical ensuring the phytotechnology potential at the selected brownfields.
Vascular access is a lifeline for hemodialysis patients. Its lifetime is affected by many hemodynamic factors such as pressure, flow regime and wall shear stress. During hemodialysis, changes in hemodynamic parameters occur due to the flow from needles inserted into the vascular system. Primarily, there is a change in shear stress that affects the vascular wall. Pathological effects of high or low WSS are known. The effect of jet from a venous needle on hemodynamics parameters was studied, but the influence of the arterial needle on hemodynamics parameters is not sufficiently studied. To understand its possible effects, we performed in vivo and in vitro studies. Methods. In vivo experiment: The existence of flow reversal around the suction needle was visualized in a group of 12 randomly selected patients using ultrasound velocity profiling (Doppler ultrasonography) during hemodialysis. In vitro experiment: The flow field was measured using the stereo particle image velocimetry method (stereo PIV). Two regimes were studied. In the first regime, the fluid in the extracorporeal circuit was pumped by a peristaltic pump. In the second regime, the continuous pump was used in the extracorporeal circuit. The conditions were set to resemble those in vascular access during a hemodialysis session. Flow volume was set to 600 mL/min for vascular access and 200 mL/min for the extracorporeal circuit. Results. The main finding of this study was that the wall in the region of the arterial needle was stressed by backflow through the arterial needle. Since this was a variable, low-shear stress loading, it was one of the risk factors for the development of stenosis. Cyclic flow reversal was apparent in all of the included hemodialysis patients. The stereo PIV in vitro experiment revealed the oscillating character of wall shear stress (WSS) inside the model. High shear stress was documented upstream of the injection point of the arterial needle. An area of very low WSS was detected right behind the injection point during a pulse of the peristaltic pump. The minimal and maximal values of the WSS during a pulse of the peristaltic pump in the observed area were −0.7 Pa and 6 Pa, respectively. The distribution of wall shear stress with the continual pump used in the extracorporeal circuit was similar to the distribution during a pulse of the peristaltic one. However, the WSS values were continual; the WSS did not oscillate. WSS ranged between 4.8 Pa and 1.0 Pa.
This study presents an experimental investigation of steels used in special knife applications, focusing on the interrelationship between chemical composition, microstructure, heat treatment, and mechanical properties. Four representative materials were analysed: VG10 (stainless steel with nickel-laminated edges and a VG10 core), RWL34TM (powder-metallurgical steel), laminated steel K110+N695 (with a nickel interlayer), and forge-welded steel K600+K720. The steels were characterised using OES, optical microscopy and SEM, supported by EDS for local chemical analysis. Microhardness testing was applied to individual structural regions to correlate carbide morphology, layer interfaces, and heat-treatment response with hardness values. The results reveal pronounced differences in structural homogeneity and defect occurrence. Powder-metallurgical RWL34TM exhibited the most uniform microstructure with finely dispersed Cr carbides, achieving high hardness and absence of structural defects. In contrast, laminated and forge-welded steels contained large primary carbides, carbide precipitation at grain boundaries, porous cavities, and insufficient cohesion in interlayers or weld zones, which may compromise toughness. VG10 and K110+N695 showed carbide coarsening caused by inadequate heat treatment, whereas K600+K720 revealed weld-related defects and heterogeneous phase structures. Overall, the study demonstrates the critical role of heat treatment and processing route in determining blade quality and performance. The findings provide guidance for optimising steel selection and processing technologies in advanced cutlery engineering.