In this contribution, we propose natural resources as a new source to acquire biocompatible AIEgens.

Combining the strategies of the reduction of the energy gap and the mechanism of aggregation-induced emission is an effective way to create red and near infrared emission molecules.

Two highly selective two-photon fluorescent probes for cysteine over homocysteine, N-acetyl-L-cysteine, dithiothreitol, glutathione and other amino acids, and their fluorescent imaging in living cells have been shown.