Aerogels are one of the most interesting materials of the 21st century owing to their high porosity, low density, and large available surface area. Historically, aerogels have been used for highly efficient insulation and niche applications, such as interstellar particle capture. Recently, aerogels have made their way into the composite universe. By coupling nanomaterial with a variety of matrix materials, lightweight, high-performance composite aerogels have been developed for applications ranging from lithium-ion batteries to tissue engineering materials. In this paper, the current status of aerogel composites based on nanomaterials is reviewed and their application in environmental remediation, energy storage, controlled drug delivery, tissue engineering, and biosensing are discussed.

A novel Au nanoparticle (AuNP)-biopolymer coated carbon screen-printed electrode (SPE) sensor was developed through the co-electrodeposition of Au and chitosan for mercury (Hg) ion detection. This new sensor showed successful Hg²⁺ detection in landfill leachate using square wave anodic stripping voltammetry (SWASV) with an optimized condition: a deposition potential of −0.6 V, deposition time of 200 s, amplitude of 25 mV, frequency of 60 Hz, and square wave step voltage of 4 mV. A noticeable peak was observed at +0.58 V associated with the stripping current of the Hg ion. The sensor exhibited a good sensitivity of ~0.09 μA/μg (~0.02 μA/nM) and a linear response over the concentration range of 10 to 100 ppb (50–500 nM). The limit of detection (LOD) was 1.69 ppb, which is significantly lower than the safety limit defined by the United States Environmental Protection Agency (USEPA). The sensor had an excellent selective response to Hg²⁺ in landfill leachate against other interfering cations (e.g., Zn²⁺, Pb²⁺, Cd²⁺, and Cu²⁺). Fifteen successive measurements with a stable peak current and a lower relative standard deviation (RSD = 5.1%) were recorded continuously using the AuNP-biopolymer-coated carbon SPE sensor, which showed excellent stability, sensitivity and reproducibility and consistent performance in detecting the Hg²⁺ ion. It also exhibited a good reliability and performance in measuring heavy metals in landfill leachate.

Microplastics (MPs) are a ubiquitous pollutant, emphasizing the need to understand their abundance and the factors that influence these patterns around the globe. In a prior study, high numbers of MPs were found in surface waters and tissues of the oyster Crassostrea virginica collected from one location in the Indian River Lagoon (IRL, FL, USA). To better understand spatial and temporal variability of MPs throughout the IRL, for one year, monthly surface water samples were collected from 35 sites, while oysters were collected quarterly from 12 sites. Microscopy and ATR-FTIR were used to quantify MP. In total, 3755 MPs were found in 44% of water samples (mean density ± CI: 1.47 ± 0.09 MP/L). South IRL water had the most MPs, likely associated with proximity to urbanization, inlets (MP sinks) and tributaries (MP sources). MP (n = 3181) were found in 70% of examined C. virginica (n = 1402). Abundances of MP in oysters were lower in the spring and in north IRL. The overall mean abundance was 2.26 ± 0.16 MP/oyster, and the density was 2.43 ± 0.52 MP/g wet tissue weight. Our results provide a more complete picture of MPs in the IRL, a subtropical, shallow-water estuarine system.

Stormwater outfalls are frequently listed as sources of microplastic (MP) contamination into aquatic systems. To date, few studies have been undertaken to determine if stormwater outfalls are MP hotspots in estuaries. This study compared the surface waters adjacent to and at least one kilometer away from stormwater outfalls of a subtropical estuarine system: the Indian River Lagoon (IRL) on the east coast of Florida, USA. Citizen scientists collected water samples monthly for 12 months from stormwater outfalls (n = 24) and control sites (n = 6). Overall, 958 MPs were identified from 1800 L of water, with the most found in the fall months during hurricane season. Stormwater outfalls (mean: 0.53 MP/L) were found to discharge smaller MPs (GLM: p = 0.0008) in significantly higher amounts compared to control sites (GLM: p = 0.02), documenting stormwater as a point-source pollutant in this system. Two types of stormwater outfalls drained into the IRL—closed culverts and open drainage channels—with no difference in MP abundances between the two (GLM: p = 0.60). Microfibers dominated collections (89%). Using ATR-FTIR for polymer identification, 80% of the materials found were plastic; polypropylene (29%), polyethylene (18%), and polyethylene terephthalate (18%) were the most abundant polymers found.

Optimizing the biological identity of nanoparticles (NPs) for efficient tumor uptake remains challenging. The controlled formation of a protein corona on NPs through protein absorption from biofluids could favor a biological identity that enables tumor accumulation. To increase the diversity of proteins absorbed by NPs, sera derived from Influenza A virus (IAV)-infected mice were used to pre-coat NPs formed using a hyperbranched polyester polymer (HBPE-NPs). HBPE-NPs, encapsulating a tracking dye or cancer drug, were treated with sera from days 3–6 of IAV infection (VS3-6), and uptake of HBPE-NPs by breast cancer cells was examined. Cancer cells demonstrated better uptake of HBPE-NPs pre-treated with VS3-6 over polyethylene glycol (PEG)-HBPE-NPs, a standard NP surface modification. The uptake of VS5 pre-treated HBPE-NPs by monocytic cells (THP-1) was decreased over PEG-HBPE-NPs. VS5-treated HBPE-NPs delivered a cancer drug more efficiently and displayed better in vivo distribution over controls, remaining stable even after interacting with endothelial cells. Using a proteomics approach, proteins absorbed from sera-treated HBPE-NPs were identified, such as thrombospondin-1 (TSP-1), that could bind multiple cancer cell receptors. Our findings indicate that serum collected during an immune response to infection is a rich source of macromolecules that are absorbed by NPs and modulate their biological identity, achieving rationally designed uptake by targeted cell types.

Nickel silicide nanoparticles were prepared in situ on carbon nanofibers through pyrolysis of electrospun fibers containing poly(acrylonitrile) (PAN, carbon fiber precursor), silazane (SiCN ceramic precursor), and nickel chloride (nickel source). SiCN ceramics produced in carbon nanofibers during the pyrolysis expanded the graphitic interlayer spacing and facilitated the diffusion of metal atoms to the fiber surfaces, leading to the formation of nickel silicide nanoparticles at a reduced temperature. In addition, nickel silicide nanoparticles catalyzed an in situ formation of carbon nanotubes, with carbon sourced from the decomposition of silazane. The method introduces a simple route to produce carbon supported metal nanoparticles for catalysis and energy storage applications.