Earth Observation (EO) data can be leveraged to estimate environmental variables that influence the transmission cycle of the pathogens that lead to mosquito-borne diseases (MBDs). The aim of this scoping review is to examine the state-of-the-art and identify knowledge gaps on the latest methods that used satellite EO data in their epidemiological models focusing on malaria, dengue and West Nile Virus (WNV). In total, 43 scientific papers met the inclusion criteria and were considered in this review. Researchers have examined a wide variety of methodologies ranging from statistical to machine learning algorithms. A number of studies used models and EO data that seemed promising and claimed to be easily replicated in different geographic contexts, enabling the realization of systems on regional and national scales. The need has emerged to leverage furthermore new powerful modeling approaches, like artificial intelligence and ensemble modeling and explore new and enhanced EO sensors towards the analysis of big satellite data, in order to develop accurate epidemiological models and contribute to the reduction of the burden of MBDs.

Mosquito-Borne Diseases (MBDs) are known to be more prevalent in the tropics, and yet, in the last two decades, they are spreading to many other countries, especially in Europe. The set (volume) of environmental, meteorological and other spatio-temporally variable parameters affecting mosquito abundance makes the modeling and prediction tasks quite challenging. Up to now, mosquito abundance prediction problems were addressed with ad-hoc area-specific and genus-tailored approaches. We propose and develop MAMOTH, a generic and accurate Machine Learning model that predicts mosquito abundances for the upcoming period (the Mean Absolute Error of the predictions do not deviate more than $14\%$). The designed model relies on satellite Earth Observation and other in-situ geo-spatial data to tackle the problem. MAMOTH is not site- nor mosquito genus-dependent; thus, it can be easily replicated and applied to multiple cases without any special parametrization. The model was applied to different mosquito genus and species Culex spp. as potential vectors for West Nile Virus, Anopheles spp. for Malaria and Aedes albopictus for Zika/Chikungunya/Dengue) and in different areas of interest (Italy, Serbia, France, Germany). The results show that the model performs accurately and consistently for all case studies. Additionally, the evaluation of different cases, with the model using the same principles, provides an opportunity for multi-case and multi-scope comparative studies.