Information on the content of medicinal plants used in the treatment of diabetes is scarce in the literature. The objectives of this study were to determine the levels of macroelements and microelements in three different medicinal plant species including the dry samples and teas from Bauhinia forficata, Eleusine Indica, and Orthosiphon stamineus and assess the human health risks of ingestion of the tea. The content of the dry samples and teas was obtained using the technique of inductively coupled plasma optical emission spectrometry (ICP OES) after microwave digestion procedure. The hazard quotient (HQ) method was used to access the human health risks posed by heavy metal through tea consumption. The results revealed the presence of K, Mg, Na, P, Al, Fe, Zn, Mn, Cu, Ni, and Se in dry samples and plant teas. The dry plants have high concentration of K and P. All dry plants contain Mg, Na, Al, Fe, Mn, Ni, Zn, and Cu above the limit permissible level set by the World Health Organization (WHO). All the hazard index (HI) values in plant teas were found to be within safe limits for human consumption (HI < 1). The plants may have possible action benefits when used in popular medicine. However, the ingestion through capsules prepared by enclosing a plant powder or teas can be harmful to the health of diabetics. The prescription of this plant for the treatment of diabetes should be treated with caution.
Viruses continued to emerge and bring challenges to the global public health system with emerging viruses with respiratory contagion. Previous studies have shown that the increased incidence of certain viral respiratory infections, including influenza and coronavirus, is associated with low levels of Vitamin D, zinc and iron. Elements such as iron, zinc and Vitamin D influence adaptive immunity by inhibiting the proliferation of B cells with differentiation and secretion of immunoglobulins that will supply the proliferation of T cells and this will result in a more pro-inflammatory response change.
7 April 2020 in International Journal of Clinical Virology
In the evolutionary journey of humanity, it is possible to verify an analysis of pandemics with high occurrences. This study aims to conduct a critical analysis of the role of Vitamin D as an endogenous vaccine in the main viruses present in humanity over the decades. To construct this text, we used the short review methodology through a critical analysis. This study demonstrated the importance of using Vitamin D as an endogenous vaccine when used frequently in both healthcare professionals and patients. Therefore, it is concluded that Vitamin acts protectively in the innate immune system.
13 June 2020 in European Journal of Medicinal Plants
Aims: To present a description of the benefits in the use of three plant models, in this case, Bauhinia forficata, Eleusine Indica and Orthosiphon stamineus Benth in the antidiabetic actions addressed through its mechanism of pharmacological and antioxidant action. Methodology: In this study, the systematic review methods was used. Results: The extracted studies totaled 146 randomized and experimental articles with rats and animals, at the end of the study extraction, only six covered all inclusion criteria and were used in the short review. Conclusion: This systematic short review on the use of Bauhiana Forficata, Eleusine Indica and Orthosiphon Stamineus Benth verified the ability to reduce the hyperglycemia of these plants in association with drug treatment in diabetic patients and, thus, brings a promising answer by decreasing worsening and has protective enzymatic and antioxidant activities thus, it favors the reduction of hyperglycemia.
31 December 2019 in International Journal for Innovation Education and Research
Colon cancer is a growing health problem in Brazil. According to data from the World Health Organization (WHO), colon cancer is among the top ten causes of mortality and morbidity in the world. Besides, the disease has a significant economic impact on the Brazilian public health system. Over the past five years, there has been an increased interest in use, isolation, characterization and determination of the biological actions of compounds such as broccoli. Experimental studies with genetically modified (GMOs) rats, mice, and rats using Sulforaphane have demonstrated their ability to prevent, delay and reverse pre-neoplastic lesions, improved survival, as well as acting on neoplastic cells with therapeutic action. Sulforaphane through activation of Nrf2 increases the activity of phase II enzymes such as glutathione S transferase (GST), which is involved in the elimination of xenobiotic compounds. Aberrant crypts are induced, in Wistar rats and mice, by genotoxic and non-genotoxic chemical compounds. Colon carcinogenesis is generally induced in rats and mice by two substances, 1,2-dimethylhydrazine (DMH) and azoxymethane (AOM). Azoxymethane is often used concerning DMH because it is more potent and requires few reactions for its activation. It is possible to conclude that Sulforaphane, through its various biological actions, presents efficiency in the prevention of colon cancer and significant potential for use in future experimental studies with genetically modified rats, mice, and rats.
24 October 2020 in European Journal of Medicinal Plants
Introduction: Bauhinia forficata, has presented in several interesting effects for the diabetic human organism as the adjuvant treatment. Its effects have been tested and proven in scientific studies in the Unified Health System in Brazil. Aims: Verify the effects of the medicinal plant Bauhinia forficata as an aid in the control of glycemic indexes. Methodology: Case report with exploratory descriptive study with a quantitative approach, using direct observation techniques of the Dáder method adapted to the use of herbal medicines such as Bauhinia forficata. Results: In this study, there was a decrease in triglyceride levels with a drop of 77%, which despite not reaching the recommended values for diabetic patients (<150 mg/dl) is quite significant. Conclusion: Bauhinia forficata used in the treatment of diabetes mellitus has anti-inflammatory actions that contribute to reduce glycated hemoglobin and, thus decrease fasting and postprandial glucose.