This page has only limited features, please log in for full access.

Unclaimed
Toshio Minematsu
Research Institute for Disease Control, Aisenkai Nichinan Hospital, 3649-2 Kazeda, Nichinan, Miyazaki 887-0034, Japan

Basic Info

Basic Info is private.

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 09 May 2021 in Viruses
Reads 0
Downloads 0

Human cytomegalovirus (CMV) is the leading cause of neurological sequelae in infants. Understanding the risk factors of primary CMV infection is crucial in establishing preventive strategies. Thus, we conducted a retrospective cohort study to identify risk factors of vertical transmission among pregnant women with immunoglobulin (Ig) M positivity. The study included 456 pregnant women with IgM positivity. Information on age, parity, occupation, clinical signs, IgM levels, and IgG avidity index (AI) was collected. The women were divided into infected and non-infected groups. The two groups showed significant differences in IgM level, IgG AI, number of women with low IgG AI, clinical signs, and number of pregnant women with single parity. In the multiple logistic regression analysis, pregnant women with single parity and low IgG AI were independent predictors. Among 40 women who tested negative for IgG antibody in their previous pregnancy, 20 showed low IgG AI in their current pregnancy. Among the 20 women, 4 had vertical transmission. These results provide better understanding of the risk factors of vertical transmission in pregnant women with IgM positivity.

ACS Style

Masatoki Kaneko; Junsuke Muraoka; Kazumi Kusumoto; Toshio Minematsu. Low Maternal Immunoglobulin G Avidity and Single Parity as Adverse Implications of Human Cytomegalovirus Vertical Transmission in Pregnant Women with Immunoglobulin M Positivity. Viruses 2021, 13, 866 .

AMA Style

Masatoki Kaneko, Junsuke Muraoka, Kazumi Kusumoto, Toshio Minematsu. Low Maternal Immunoglobulin G Avidity and Single Parity as Adverse Implications of Human Cytomegalovirus Vertical Transmission in Pregnant Women with Immunoglobulin M Positivity. Viruses. 2021; 13 (5):866.

Chicago/Turabian Style

Masatoki Kaneko; Junsuke Muraoka; Kazumi Kusumoto; Toshio Minematsu. 2021. "Low Maternal Immunoglobulin G Avidity and Single Parity as Adverse Implications of Human Cytomegalovirus Vertical Transmission in Pregnant Women with Immunoglobulin M Positivity." Viruses 13, no. 5: 866.