Marzena Pabich

Dr. Marzena Pabich

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 July 2019 in Nutrients
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Journal Article
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MPMarzena Pabich
Marzena Pabich
MMMałgorzata Materska
Małgorzata Materska
Scientific advancements in recent years have shed new light on the relationship between diet and human health. Nutrients play an important role in the prevention of many civilization diseases, such as osteoporosis, type II diabetes, hypercholesterolemia, and cardiovascular diseases. The biological activity of natural plant components allows their use in the treatment of various diseases, especially civilization diseases, to be speculated. Special attention is paid to phenolic compounds that have numerous health-promoting properties. Isoflavones, phenolic compounds, are commonly found in legumes, especially in soybeans. Their structural similarity to 17-β-estradiol (E2), the main female sex hormone, allows them to induce estrogenic and antiestrogenic effects by binding to estrogen receptors, and their consumption has been associated with a decreased risk of hormone-related cancers. In addition, numerous epidemiological studies and related meta-analyses suggest that soy consumption may be associated with a lower incidence of certain diseases. However, there are some doubts about the potential effects on health, such as the effectiveness of cardiovascular risk reduction or breast cancer-promoting properties. The purpose of this review is to present the current knowledge on the potential effects of soy isoflavone consumption with regard to civilization diseases.

18 September 2020 in Applied Sciences
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JGJacek Gawroński
Jacek Gawroński
JŻJadwiga Żebrowska
Jadwiga Żebrowska
MPMarzena Pabich
Marzena Pabich
IJIzabella Jackowska
Izabella Jackowska
KKKrzysztof Kowalczyk
Krzysztof Kowalczyk
MDMagdalena Dyduch-Siemińska
Magdalena Dyduch-Siemińska
The phytochemical characteristic analysis of a group of 30 haskap berry genotypes was carried out bearing in mind the concern for the consumption of food with high nutraceutical value that helps maintain good health. Phytochemical fruit composition and antioxidant activity were assessed by the Folin–Ciocalteau, spectrophotometric, DPPH (1,1-diphenyl-2-picrylhydrazyl) as well as ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) method. Evaluation of antioxidant activity was referred to as the Trolox equivalent. The observed differences in the content of phenolics, flavonoids, vitamin C and antioxidant activity allowed us to select genotypes which, due to the high level of the analyzed compounds, are particularly recommended in everyone’s diet. In addition, the analysis of the prospects of increasing the analyzed phytochemical properties, estimated by parameters such as heritability and genetic progress, indicates the effectiveness of breeding in relation to each of the analyzed traits. The results of the presented research can be used in the implementation of future breeding programs for this valuable species.

25 August 2022 in Molecules
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Journal Article
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MMMałgorzata Materska
Małgorzata Materska
MPMarzena Pabich
Marzena Pabich
Monika Sachadyn-KrólMonika Sachadyn-Król
Monika Sachadyn-Król
AKAgata Konarska
Agata Konarska
EWElżbieta Weryszko-Chmielewska
Elżbieta Weryszko-Chmielewska
MDMarta Dmitruk
Marta Dmitruk
Natural defensive substances synthesized by plants that could replace synthetic pesticides in the protection of plants against insect invasions are constantly being sought. The study assessed changes in the qualitative and quantitative composition of secondary metabolites in horse chestnut leaves collected in different locations and differing in the sensitivity of the plant to the invasion by the horse-chestnut leaf miner. An attempt was made to identify compounds that are most responsible for the increased plant resistance to this threat. Additionally, changes in the anatomy of chestnut leaves affected by the pest were presented. It was noticed that the trees differed in the composition of secondary metabolites already in the initial growing season, which should be related to the influence of habitat conditions. The analysis of the profile of the compounds in non-infested and infested horse chestnut leaves revealed a clear response of the plant to the stress factor, i.e., the foraging of the horse-chestnut leaf miner. Catechins seem to be compounds involved in plant resistance. The leaf anatomy showed enhanced accumulation of phenolic compounds at the pest foraging sites. Hypertrophy and thickened and cracked cell walls of the spongy parenchyma were visible in the vicinity of the mines.

18 August 2022 in Food Chemistry
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Journal Article
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MKMarek Kowalczyk
Marek Kowalczyk
PDPiotr Domaradzki
Piotr Domaradzki
MMMałgorzata Materska
Małgorzata Materska
MFMariusz Florek
Mariusz Florek
A(Agnieszka Kaliniak-Dziura (Kaliniak)
Agnieszka Kaliniak-Dziura (Kaliniak)
MPMarzena Pabich
Marzena Pabich
The occurrence of the DFD defect shortens microbiological stability and reduces consumer acceptance of meat. The effect of a chokeberry leaf extract (ChLE) addition at concentrations of 0.01 %, 0.05 % and 0.1 % on the sensory and physicochemical properties of burgers prepared from DFD meat during refrigerated storage under vacuum for 10 days was assessed. The pH, water activity, texture, colour, degree of lipid oxidation, and content of α-tocopherol were measured. The extract at concentrations of 0.05 % and 0.1 % significantly influenced lower levels of lipid oxidation and higher content of α-tocopherol on each tested period. Moreover, these concentrations had a beneficial effect on the instrumental and sensory evaluation of texture parameters and on overall quality. It was concluded that the addition of 0.1 % extract was the most beneficial over the entire 10-day storage period. In summary, use of ChLE may reduce the loss of raw meat caused by DFD defect.

1 November 2021 in Applied Sciences
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MPMarzena Pabich
Marzena Pabich
BMBeata Marciniak
Beata Marciniak
RKRenata Kontek
Renata Kontek
The objective of this study was to determine the potential of dry extracts from soybean pods as a source of bioactive compounds. The phenolic compound composition of the extract (E) and fraction (F1-F3) as well as their respective lipophilicity were analyzed by UPLC-ESI-QTOF-MS. The biological activity as measured by antioxidant and cytotoxic activity was also evaluated. The in vitro anticancer potential of the ethanolic extract and fraction of soybean pods was measured through MTT assay using human colorectal carcinoma (HTC-116) and prostate cancer (PC-3) cell lines. The F2 fraction, with medium lipophilicity, produced the most pronounced cytotoxic effect in PC-3 cells. Analysis of Pearson’s correlation demonstrated a high relationship between the content of phenolic compounds, the antioxidant activity of the extract and fractions, and cytotoxic activity towards PC-3 cells. UPLC-ESI-QTOF-MS analysis of soybean pod extract resulted in putative identification of 50 polyphenols belonging to three different chemical families (phenolic acids, flavonoids, and other polyphenols), the first time such an analysis has been performed. Among the fractions with variable lipophilicity, fraction F2 was the most abundant in phenolic compounds. This was confirmed in the quantitative analysis, as a result of which the highest total content of phenolic compounds was found in the extract (E) and fraction F2. Soybean pods might be useful material for obtaining preparations with anti-radical and anti-cancer properties. They can also be an active food additive or a component in dietary supplements.

9 December 2021 in Acta Scientiarum Polonorum Hortorum Cultus
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Journal Article
Open access
JŻJadwiga Żebrowska
Jadwiga Żebrowska
MDMagdalena Dyduch-Siemińska
Magdalena Dyduch-Siemińska
JGJacek Gawroński
Jacek Gawroński
IJIzabella Jackowska
Izabella Jackowska
MPMarzena Pabich
Marzena Pabich
The strawberry fruit market increasingly demands new cultivars producing berries with enhanced bioactive attributes. In this research the suitability of twelve strawberry cultivars for effective breeding aimed at the enhancement of bioactive fruit attributes was studied. The group of genotypes with different pedigree was examined in respect of variation, breeding parameters, correlation between the content of bioactive compounds and the antioxidant capacity of fruit. Pre-breeding research showed the highly significant differences between genotypes regarding all traits analysed. Relationship between the bioactive phytochemicals content and antioxidant capacity of fruit were mostly positive and significant. Only correlation between vitamin C and flavonoids was negative (−0.482). Path analysis exhibited the highest positive direct effect of total phenolic content on antioxidant capacity (0.609). Heritability of traits was very high, reaching values above 0.90. The highest genetic advance was observed for flavonoids. Results suggested that the genotype plays the main role in shaping of fruit antioxidant potential. This study indicated that the efficient strawberry breeding focused on obtaining the forms with enhanced bioactive berry properties could be highly possible.