Deep learning (DL) is a branch of machine learning and artificial intelligence that has been applied to many areas in different domains such as health care and drug design. Cancer prognosis estimates the ultimate fate of a cancer subject and provides survival estimation of the subjects. An accurate and timely diagnostic and prognostic decision will greatly benefit cancer subjects. DL has emerged as a technology of choice due to the availability of high computational resources. The main components in a standard computer-aided design (CAD) system are preprocessing, feature recognition, extraction and selection, categorization, and performance assessment. Reduction of costs associated with sequencing systems offers a myriad of opportunities for building precise models for cancer diagnosis and prognosis prediction. In this survey, we provided a summary of current works where DL has helped to determine the best models for the cancer diagnosis and prognosis prediction tasks. DL is a generic model requiring minimal data manipulations and achieves better results while working with enormous volumes of data. Aims are to scrutinize the influence of DL systems using histopathology images, present a summary of state-of-the-art DL methods, and give directions to future researchers to refine the existing methods.

Diabetic retinopathy (DR) is a worldwide problem associated with the human retina. It leads to minor and major blindness and is more prevalent among adults. Automated screening saves time of medical care specialists. In this work, we have used different deep learning (DL) based 3D convolutional neural network (3D‐CNN) architectures for binary and multiclass (5 classes) classification of DR. We have considered mild, moderate, no, proliferate, and severe DR categories. We have deployed two artificial data augmentation/enhancement methods: random weak Gaussian blurring and random shift along with their combination to accomplish these tasks in the spatial domain. In the binary classification case, we have found the performance of 3D‐CNN architecture trained by deploying combined augmentation methods to be the best, while in the multiclass case, the performance of model trained without augmentation is the best. It is observed that the DL algorithms working with large volumes of data may achieve better performances as compared to the methods working with small volumes of data.

Automatic modulation classification is a task that is essentially required in many intelligent communication systems such as fibre‐optic, next‐generation 5G or 6G systems, cognitive radio as well as multimedia internet‐of‐things networks etc. Deep learning (DL) is a representation learning method that takes raw data and finds representations for different tasks such as classification and detection. DL techniques like Convolutional Neural Networks (CNNs) have a strong potential to process and analyse large chunks of data. In this work, we considered the problem of multiclass (eight classes) classification of modulated signals, which are, Binary Phase Shift Keying, Quadrature Phase Shift Keying, 16 and 64 Quadrature Amplitude Modulation corrupted by Additive White Gaussian Noise, Rician and Rayleigh fading channels using 3D‐CNN architectures in both frequency and spatial domains while deploying three approaches for data augmentation, which are, random zoomed in/out, random shift and random weak Gaussian blurring augmentation techniques with a cross‐validation (CV) based hyperparameter selection statistical approach. Simulation results testify the performance of 10‐fold CV without augmentation in the spatial domain to be the best while the worst performing method happens to be 10‐fold CV without augmentation in the frequency domain and we found learning in the spatial domain to be better than learning in the frequency domain.

Alzheimer’s disease (AD) is a global health issue that predominantly affects older people. It affects one’s daily activities by modifying neural networks in the brain. AD is categorized by the death of neurons, the creation of amyloid plaques, and the development of neurofibrillary tangles. In clinical settings, an early diagnosis of AD is critical to limit the problems associated with it and can be accomplished using neuroimaging modalities, such as magnetic resonance imaging (MRI) and positron emission tomography (PET). Deep learning (DL) techniques are widely used in computer vision and related disciplines for various tasks such as classification, segmentation, detection, etc. CNN is a sort of DL architecture, which is normally useful to categorize and extract data in the spatial and frequency domains for image-based applications. Batch normalization and dropout are commonly deployed elements of modern CNN architectures. Due to the internal covariance shift between batch normalization and dropout, the models perform sub-optimally under diverse scenarios. This study looks at the influence of disharmony between batch normalization and dropout techniques on the early diagnosis of AD. We looked at three different scenarios: (1) no dropout but batch normalization, (2) a single dropout layer in the network right before the softmax layer, and (3) a convolutional layer between a dropout layer and a batch normalization layer. We investigated three binaries: mild cognitive impairment (MCI) vs. normal control (NC), AD vs. NC, AD vs. MCI, one multiclass AD vs. NC vs. MCI classification problem using PET modality, as well as one binary AD vs. NC classification problem using MRI modality. In comparison to using a large value of dropout, our findings suggest that using little or none at all leads to better-performing designs.

Alzheimer’s disease (AD) is a leading health concern affecting the elderly population worldwide. It is defined by amyloid plaques, neurofibrillary tangles, and neuronal loss. Neuroimaging modalities such as positron emission tomography (PET) and magnetic resonance imaging are routinely used in clinical settings to monitor the alterations in the brain during the course of progression of AD. Deep learning techniques such as convolutional neural networks (CNNs) have found numerous applications in healthcare and other technologies. Together with neuroimaging modalities, they can be deployed in clinical settings to learn effective representations of data for different tasks such as classification, segmentation, detection, etc. Image filtering methods are instrumental in making images viable for image processing operations and have found numerous applications in image-processing-related tasks. In this work, we deployed 3D-CNNs to learn effective representations of PET modality data to quantify the impact of different image filtering approaches. We used box filtering, median filtering, Gaussian filtering, and modified Gaussian filtering approaches to preprocess the images and use them for classification using 3D-CNN architecture. Our findings suggest that these approaches are nearly equivalent and have no distinct advantage over one another. For the multiclass classification task between normal control (NC), mild cognitive impairment (MCI), and AD classes, the 3D-CNN architecture trained using Gaussian-filtered data performed the best. For binary classification between NC and MCI classes, the 3D-CNN architecture trained using median-filtered data performed the best, while, for binary classification between AD and MCI classes, the 3D-CNN architecture trained using modified Gaussian-filtered data performed the best. Finally, for binary classification between AD and NC classes, the 3D-CNN architecture trained using box-filtered data performed the best.