The surface topography of medical implants plays an important role in the regulation of cellular responses. Microstructure and nanostructure surfaces have been proved to enhance cell spreading and proliferation with respect to smooth surfaces. In this study, we fabricated a new structure including micro-pits and nano-pits on the surface of titanium via sandblasting, acid etching and chemical oxidation to investigate the influence of composite structures on cell behavior. Meanwhile, the surface properties and corrosion resistance of treated samples were also tested. The micro/nanostructured titanium surface comprising of micro-pits and nano-pits presented enhanced roughness and hydrophilicity. In addition, the corrosion resistance of the titanium substrate with micro-pits and nano-pits was significantly improved compared to that of polished titanium. More importantly, the micro/nanostructured titanium surface proved a good interfacial environment to promote osteoblast functions such as cell adhesion and spreading. Taken together, these results showed that the construction of micro/nanostructure on the titanium surface is an effective modification strategy to improve osteoblast cell responses.

This study focuses on an experimental device for the adaptive adjustment of the preload of high-speed motorized spindles. Firstly, based on Hirano’s criterion, the optimal preload for bearings at different rotational speeds was determined, and an adaptive preload adjustment mechanism was developed, with its accuracy experimentally validated. Secondly, the optimal lubrication conditions were obtained by a single-factor experiment. Then, the vibration characteristics under different preload conditions were explored, and the axial displacement variations were analyzed across a range of rotational speeds. Finally, the temperature rise in the bearings with the speed at the constant preload force and the optimal preload force were compared. The results demonstrated that the adaptive preload adjustment device outperformed the constant preload application. In teaching practice, this study enhanced students’ systematic understanding of the adaptive preload adjustment process in motorized spindles, promoted the integration of theoretical knowledge with practical application, and strengthened their learning interest. In addition, this device can provide experimental equipment for studying the performance of high-speed motorized spindles and bearings in scientific research.