Nathalie Bernoud-Hubac

Dr. Nathalie Bernoud-Hubac

Contact and Structure Mechanics Laboratory LaMCoS, UMR 5259 INSA Lyon – CNRS, Institut Multidisciplinaire de Biochimie des Lipides, Campus LyonTech La Doua - INSA Lyon, 69621 Villeurbanne, France
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Biography

Nathalie Bernoud-Hubac is a Professor of Biochemistry at INSA Lyon (France). She is Head of the “Mechanics, Lipidomics and Engineering for Health” team of Contacts and Structural Mechanics Laboratory (LaMCoS) (a mixed unit of INSA/CNRS Research) and the director of a Functional Lipidomics Platform (Institute for Multidisciplinary Biochemistry of Lipids, IMBL/LaMCoS–INSA Lyon). The main objectives of the Mecalips team are to understand the pathophysiological mechanisms of chronic diseases better (from molecular to macroscopic scales), to detect early pathological dysfunctions combining biochemistry and biomechanics techniques, and to develop new strategies for the prevention and control of these chronic diseases via bioengineered structured lipids. The pathologies targeted are mainly pulmonary, vascular, articular, and neurological pathologies. Her research interests span both lipids and human health. More specifically, her work focuses on omega-3 polyunsaturated fatty acids, especially docosahexaenoic acid (DHA), which is uniquely enriched in the brain and is required for normal cerebral development and learning in humans. Deficiency in DHA level in the brain is linked with the emergence of neurodegenerative diseases. Efficient delivery of DHA into the brain is therefore necessary to prevent brain dysfunction. Her current research examines brain targeting with structured phospholipids containing DHA and the potential of these molecules as neuroprotective agents.

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