Eduard Bezuglov

Dr. Eduard Bezuglov

Department of Sports Medicine and Medical Rehabilitation, Sechenov First Moscow State Medical University of the Ministry of the Russia Federation, 119991 Moscow, Russia
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Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Aleksandra ŻebrowskaAleksandra Żebrowska
Aleksandra Żebrowska
ESEwa Sadowska-Krępa
Ewa Sadowska-Krępa
Arkadiusz StanulaArkadiusz Stanula
Arkadiusz Stanula
Zbigniew WaśkiewiczZbigniew Waśkiewicz
Zbigniew Waśkiewicz
OŁOlga Łakomy
Olga Łakomy
Beat KnechtleBeat Knechtle
Beat Knechtle
The beneficial adaptation of skeletal muscle function to strenuous exercise is partially attributable to the improvement of vitamin D status. The present study aimed to evaluate the effects of a 3-week vitamin D supplementation on serum 25(OH)D levels and skeletal muscle biomarkers (i.e. troponin, myoglobin, creatine kinase and lactic dehydrogenase) of endurance runners. A double-blind placebo-controlled study design was used and vitamin D supplementation was compared to a non-treatment control group. Twenty-four runners, competitors of the ultra-marathons held during the National Running Championships, were randomly assigned into two groups supplemented with the dose of 2000 IU vitamin D or placebo for three weeks. All subjects participated in three exercise protocols: (a) incremental exercise test (to determine the maximum oxygen uptake and the intensity of eccentric exercise), (b) eccentric exercise before and (c) after two dietary protocols. Venous blood samples were drawn at rest, immediately after the exercise and after 1 h and 24 h of recovery in order to estimate serum 25(OH)D levels, skeletal muscle biomarkers, proinflammatory cytokines and tumor necrosis factor-alpha (TNF-α) levels. A two-way ANOVA was used to test main effects and their interactions and Pearson correlation coefficients were analyzed to determine the effects of inter-variable relationships. Significant differences between pre- and post-intervention in baseline 25(OH)D levels were observed (34.9 ± 4.7 versus 40.3 ± 4.9 ng/ml, p = 0.02) in supplemented group. A higher post intervention 25(OH)D level was observed after vitamin D diet compared to placebo (40.3 ± 4.9 versus 31.8 ± 4.2 ng/mL, respectively; p < 0.05). The vitamin D supplementation decreased post-exercise (TN max) and 1 h post-exercise troponin (p = 0.004, p = 0.03, respectively), 1 h post-exercise myoglobin concentration (p = 0.01) and TNF-α levels(p < 0.03). 24 h post exercise creatine kinase activity was significantly lower in supplemented group compared to placebo (p < 0.05). A negative correlation was observed between post exercise 25(OH)D levels and myoglobin levels (r = − 0.57; p = 0.05), and 25(OH)D levels and TNFα (r = − 0.58; p = 0.05) in vitamin D supplemented group. Three weeks of vitamin D supplementation had a positive effect on serum 25(OH)D levels in endurance trained runners and it caused a marked decrease in post-exercise biomarkers levels. We concluded that vitamin D supplementation might play an important role in prevention of skeletal muscle injuries following exercise with eccentric muscle contraction in athletes.

8 October 2022 in Sports
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RMRyland Morgans
Ryland Morgans
Eduard BezuglovEduard Bezuglov
Eduard Bezuglov
POPatrick Orme
Patrick Orme
KBKyler Burns
Kyler Burns
DRDavid Rhodes
David Rhodes
Rafael OliveiraRafael Oliveira
Rafael Oliveira
The present study aimed to assess the physical match performance among senior and youth soccer players from an elite Scottish Premiership club during the 2021/2022 season. Twenty-two first team (25.9 ± 4.5 years, 78.3 ± 8.2 kg, 1.82 ± 0.07 cm) and 16 youth players (16.8 ± 0.9 years, 70.1 ± 6.8 kg, 177 ± 5.8 cm) were examined. A selection of physical match performance variables were measured using a global positioning system. Linear mixed-effect regressions revealed for all examined variables no significant differences between first team and U-18 players and no significant differences between playing level by position interaction. Across both teams, Centre Backs compared to Wing Backs, showed a 295 m (p < 0.01) lower high-intensity distance, and performed on average 36 fewer very-high intensity decelerations (p = 0.03). Comparing to Wide Midfielders, Centre Backs showed lower total (1297 m, p = 0.01), high-intensity (350 m, p = 0.01), and sprint (167 m, p < 0.01) distances. Sprint distance was also lower in Centre Backs vs. Strikers (118 m, p = 0.03), and in Central Midfielders vs. both Strikers (104 m, p = 0.03) and Wide Midfielders (154 m, p = 0.01). The present findings highlight the physical match performance of elite Scottish players and provide useful information within the context of understanding how methods of physical development of youth soccer are implemented in different countries.

11 September 2019 in International Orthopaedics
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EGEvgeny Goncharov
Evgeny Goncharov
OKOleg Aleksandrovich Koval
Oleg Aleksandrovich Koval
VDVadim Erikovich Dubrov
Vadim Erikovich Dubrov
Eduard BezuglovEduard Bezuglov
Eduard Bezuglov
AFAnastasiya Mikhaylovna Filimonova
Anastasiya Mikhaylovna Filimonova
NGNikolay Gavriilovich Goncharov
Nikolay Gavriilovich Goncharov

8 October 2019 in Nutrients
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Eduard BezuglovEduard Bezuglov
Eduard Bezuglov
ATAleksandra Tikhonova
Aleksandra Tikhonova
AZAnastasiya Zueva
Anastasiya Zueva
VKVladimir Khaitin
Vladimir Khaitin
Zbigniew WaśkiewiczZbigniew Waśkiewicz
Zbigniew Waśkiewicz
Beat KnechtleBeat Knechtle
Beat Knechtle
Vitamin D (25(OH)D) insufficiency and deficiency are highly prevalent in adult soccer players and can exceed 80% even in regions with high insolation; however, the treatment of this condition is often complicated. The aim of the present study was to examine the prevalence of vitamin D insufficiency and deficiency in youth Russian soccer players and the efficacy of its treatment. Participants were 131 young male football players (age 15.6 ± 2.4 years). Low vitamin D levels (below 30 ng/mL) were observed in 42.8% of the analyzed participants. These athletes were split in two groups composed of persons with vitamin D deficiency (serum vitamin D below 21 ng/mL) and insufficiency (serum vitamin D in range of 21–29 ng/mL). A dietary supplement of 5000 IU cholecalciferol per day was administered for two months. After the treatment, an average 92% increase in vitamin D concentration was observed (before treatment—19.7 ± 5.4 ng/mL, after treatment—34.7 ± 8.6 ng/mL, p < 0.001) and 74% of the post-treatment values were within the reference range (30–60 ng/mL). Serum concentration of vitamin D increased by 200% ± 98% (p < 0.001) during the first month of treatment with vitamin D deficiency and insufficiency being successfully treated in 83% of the football players. In summary, the prevalence of vitamin D insufficiency and deficiency was high in young Russian soccer players. Furthermore, it was indicated that the daily usage of cholecalciferol in a dose 5000 IU was an effective and well-tolerated treatment for vitamin D insufficiency. No linear dependency between the duration of treatment and increase in vitamin 25(OH)D concentration was observed.

Eduard BezuglovEduard Bezuglov
Eduard Bezuglov
ALArtemii Lazarev
Artemii Lazarev
VKVladimir Khaitin
Vladimir Khaitin
SCSergey Chegin
Sergey Chegin
ATAleksandra Tikhonova
Aleksandra Tikhonova
Zbigniew WaśkiewiczZbigniew Waśkiewicz
Zbigniew Waśkiewicz
There is now compelling evidence of the effectiveness of a range of post-exercise recovery techniques, including extended nights of sleep, cold water immersion, massage, and compression garments. Currently, limited information is available on post-exercise recovery methods used by elite endurance athletes. Therefore, this study investigated the actual methods of recovery used in this group of athletes. Google Forms were used to collect information on the recovery methods used by elite endurance track and field athletes (n = 153, 61.4% men, 38.6% women; average age: 22.7 ± 4.6 years). The most used methods of recovery were sauna bathing (96.7%), massage (86.9%), daytime nap (81.0%), and long night sleep (at least 9h) (61.4%). Recovery methods with proven effectiveness such as cold water immersion and compression garments were rarely used (15.0% and 7.8%, respectively). Overall, recovery methods were used more often when the tiers of the track and field athletes were higher. Massage and sauna bathing were the most used methods of post-exercise recovery among Russian endurance track and field athletes. In most cases, they were used in conjunction with short daytime nap and long night sleep. Higher tier athletes were more likely to use sauna bathing, massage, long night sleep, and daytime nap but not cold water immersion and compression garments as recovery methods; however, all these methods except for cold water immersion were widely used among elite-tier athletes.

28 April 2020 in International Orthopaedics
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Journal Article
Closed access
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Eduard BezuglovEduard Bezuglov
Eduard Bezuglov
ATAleksandra Tikhonova
Aleksandra Tikhonova
PCPh. V. Chubarovskiy
Ph. V. Chubarovskiy
АRА. D. Repetyuk
А. D. Repetyuk
VKVladimir Khaitin
Vladimir Khaitin
EUE. M. Usmanova
E. M. Usmanova