Antibiotics are regarded as a miracle in the medical field as it prevents disease caused by pathogenic bacteria. Since the discovery of penicillin, antibiotics have become the foundation for modern medical discoveries. However, bacteria soon became resistant to antibiotics, which puts a burden on the healthcare system. Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most prominent antibiotic-resistant bacteria in the world since 1961. MRSA primarily developed resistance to beta-lactamases antibiotics and can be easily spread in the healthcare system. Thus, alternatives to combat MRSA are urgently required. Antimicrobial peptides (AMPs), an innate host immune agent and silver nanoparticles (AgNPs), are gaining interest as alternative treatments against MRSA. Both agents have broad-spectrum properties which are suitable candidates for controlling MRSA. Although both agents can exhibit antimicrobial effects independently, the combination of both can be synergistic and complementary to each other to exhibit stronger antimicrobial activity. The combination of AMPs and AgNPs also reduces their own weaknesses as their own, which can be developed as a potential agent to combat antibiotic resistance especially towards MRSA. Thus, this review aims to discuss the potential of antimicrobial peptides and silver nanoparticles towards controlling MRSA pathogen growth.

Currently, efforts to address the energy needs of large-scale power applications have expedited the development of sodium–ion (Na–ion) batteries. Transition-metal oxides, including Mn₂O₃, are promising for low-cost, eco-friendly energy storage/conversion. Due to its high theoretical capacity, Mn₂O₃ is worth exploring as an anode material for Na-ion batteries; however, its actual application is constrained by low electrical conductivity and capacity fading. Herein, we attempt to overcome the problems related to Mn₂O₃ with heteroatom-doped reduced graphene oxide (rGO) aerogels synthesised via the hydrothermal method with a subsequent freeze-drying process. The cubic Mn₂O₃ particles with an average size of 0.5–1.5 µm are distributed to both sides of heteroatom-doped rGO aerogels layers. Results indicate that heteroatom-doped rGO aerogels may serve as an efficient ion transport channel for electrolyte ion transport in Mn₂O₃. After 100 cycles, the electrodes retained their capacities of 242, 325, and 277 mAh g⁻¹, for Mn₂O₃/rGO, Mn₂O₃/nitrogen-rGO, and Mn₂O₃/nitrogen, sulphur-rGO aerogels, respectively. Doping Mn₂O₃ with heteroatom-doped rGO aerogels increased its electrical conductivity and buffered volume change during charge/discharge, resulting in high capacity and stable cycling performance. The synergistic effects of heteroatom doping and the three-dimensional porous structure network of rGO aerogels are responsible for their excellent electrochemical performances.

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.

Owing to their high theoretical capacity, transition-metal oxides have received a considerable amount of attention as potential anode materials in sodium-ion (Na-ion) batteries. Among them, Mn₃O₄ has gained interest due to the low cost of raw materials and the environmental compatibility. However, during the insertion/de-insertion process, Mn₃O₄ suffers from particle aggregation, poor conductivity, and low-rate capability, which, in turn, limits its practical application. To overcome these obstacles, we have successfully prepared Mn₃O₄ nanoparticles distributed on the nitrogen (N)-doped and nitrogen, sulphur (N,S)-doped reduced graphene oxide (rGO) aerogels, respectively. The highly crystalline Mn₃O₄ nanoparticles, with an average size of 15–20 nm, are homogeneously dispersed on both sides of the N-rGO and N,S-rGO aerogels. The results indicate that the N-rGO and N,S-rGO aerogels could provide an efficient ion transport channel for electrolyte ion stability in the Mn₃O₄ electrode. The Mn₃O₄/N- and Mn₃O₄/N,S-doped rGO aerogels exhibit outstanding electrochemical performances, with a reversible specific capacity of 374 and 281 mAh g⁻¹, respectively, after 100 cycles, with Coulombic efficiency of almost 99%. The interconnected structure of heteroatom-doped rGO with Mn₃O₄ nanoparticles is believed to facilitate fast ion diffusion and electron transfer by lowering the energy barrier, which favours the complete utilisation of the active material and improvement of the structure’s stability.

Luminescence and SERS signals are simultaneously enhanced with a single excitation wavelength by co-encapsulating silicon quantum dots and Au–Ag alloy nanoparticles encoded with Raman reporter molecules inside polymeric nanoparticles.

Gold nanoparticles (AuNPs) have emerged as a promising application in aquaculture. Their nano-sized dimensions, comparable to pathogens offer potential solutions for combating antibiotic resistance. In this study, AuNPs were synthesized by using polychaetes, Marphysa moribidii as the bio-reducing agent. Modifications were made to reduce agglomeration in green-synthesized AuNPs through ultrasonication. The antibacterial activities of AuNPs against V. parahaemolyticus were evaluated. The physicochemical characteristics of the green synthesized AuNPs were comprehensively investigated. The successful formation of AuNPs was confirmed by the appearance of a red ruby colour and the presence of surface Plasmon resonance (SPR) absorption peaks at 530 nm as observed from UV–vis spectroscopy. Scanning electron microscopy (SEM) revealed spherical-shaped AuNPs with some agglomerations. Transmission electron microscopy (TEM) showed particle size of AuNPs ranging from 10 nm to 60 nm, meanwhile dynamic light scattering (DLS) analysis indicated an average particle size of 24.36 nm. X-ray diffraction (XRD) analysis confirmed the high crystallinity of AuNPs, and no AuNPs were detected in the polychaetes extracts prior to synthesis. A brief ultrasonication significantly reduced the tendencies for AuNPs to coalesce. The green-synthesized AuNPs demonstrated a remarkable antibacterial efficacy against V. parahaemolyticus. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests revealed that a concentration of 0.3 g/ml of AuNPs effectively inhibited V. parahaemolyticus. These findings highlighted the potential of green-synthesized AuNPs as antibacterial agents for the prevention and management of AHPND in aquaculture.