Black people are disproportionately affected by cancer incidence and mortality yet underrepresented in cancer clinical trials.
1,2 Black individuals may be less willing to participate in trials owing to barriers that disproportionately affect this group, such as low health literacy, financial burden, mistrust in clinicians, and group-based medical suspicion (ie, belief that members of one’s racial group should be suspicious of the health care system).
3,4 However, minorities who are eligible and invited to participate in a trial are as likely to enroll as White patients, suggesting that enrollment disparities may stem from clinician-level or system-level factors, such as restrictive eligibility criteria or physicians’ reluctance to discuss trials with Black patients.
3,5,6