Lawrence Le

Prof. Lawrence Le

orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 November 2008 in Scoliosis and Spinal Disorders
Verified
Journal Article
Open access
PDF file
GLGabrielle C Lam
Gabrielle C Lam
DHDoug L Hill
Doug L Hill
LLLawrence Le
Lawrence Le
JRJim V Raso
Jim V Raso
ELEdmond Lou
Edmond Lou
Current research has provided a more comprehensive understanding of Adolescent Idiopathic Scoliosis (AIS) as a three-dimensional spinal deformity, encompassing both lateral and rotational components. Apart from quantifying curve severity using the Cobb angle, vertebral rotation has become increasingly prominent in the study of scoliosis. It demonstrates significance in both preoperative and postoperative assessment, providing better appreciation of the impact of bracing or surgical interventions. In the past, the need for computer resources, digitizers and custom software limited studies of rotation to research performed after a patient left the scoliosis clinic. With advanced technology, however, rotation measurements are now more feasible. While numerous vertebral rotation measurement methods have been developed and tested, thorough comparisons of these are still relatively unexplored. This review discusses the advantages and disadvantages of six common measurement techniques based on technology most pertinent in clinical settings: radiography (Cobb, Nash-Moe, Perdriolle and Stokes' method) and computer tomography (CT) imaging (Aaro-Dahlborn and Ho's method). Better insight into the clinical suitability of rotation measurement methods currently available is presented, along with a discussion of critical concerns that should be addressed in future studies and development of new methods.


1 October 2020 in Journal of Colloid and Interface Science
Verified
Journal Article
Closed access
JYJiaqiang Yi
Jiaqiang Yi
KNKim-Cuong T. Nguyen
Kim-Cuong T. Nguyen
WWWenda Wang
Wenda Wang
WYWenshuai Yang
Wenshuai Yang
MPMingfei Pan
Mingfei Pan
HZHongbo Zeng
Hongbo Zeng

8 November 2022 in Journal of Dentistry
Verified
Journal Article
Closed access
MLMengxun Li
Mengxun Li
KPKumaradevan Punithakumar
Kumaradevan Punithakumar
PMPaul W Major
Paul W Major
LLLawrence Le
Lawrence Le
KNKim Cuong Nguyen
Kim Cuong Nguyen
FAFabiana T Almeida
Fabiana T Almeida

3 October 2018 in PLOS ONE
Verified
Journal Article
Open access
PDF file
KNKim-Cuong T Nguyen
Kim-Cuong T Nguyen
CPCamila Pachêco-Pereira
Camila Pachêco-Pereira
NKNeelambar R Kaipatur
Neelambar R Kaipatur
JCJune Cheung
June Cheung
PMPaul W Major
Paul W Major
LLLawrence Le
Lawrence Le
The current methods to image alveolar bone in humans include intraoral 2D radiography and cone-beam computed tomography (CBCT). However, these methods expose the subject to ionizing radiation. Therefore, ultrasound imaging has been investigated as an alternative technique, as it is both non-invasive and free from ionizing radiation. In order to assess the validity and reliability of ultrasonography in visualizing alveolar bone, a systematic review was conducted comparing ultrasound imaging to CBCT for examination of the alveolar bone level. Seven databases were searched. Studies addressing examination of alveolar bone level via CBCT and ultrasound were selected. Risk of bias under Cochrane guidelines was used as a methodological quality assessment tool. All the four included studies were ex vivo studies that used porcine or human cadaver samples. The alveolar bone level was measured by the distance from the alveolar bone crest to certain landmarks such as cemento-enamel junction or gingival margin. The risk of bias was found as low. The mean difference between ultrasound and CBCT measurements ranged from 0.07 mm to 0.68 mm, equivalent to 1.6% - 8.8%. There is currently preliminary evidence to support the use of ultrasonography as compared to CBCT for the examination of alveolar bone level. Further studies comparing ultrasound to gold standard methods would be necessary to help validate the accuracy of ultrasonography as a diagnostic technique in periodontal imaging.

9 May 2016 in Annals of Biomedical Engineering
Verified
Journal Article
Closed access
PDF file
KNKim-Cuong T. Nguyen
Kim-Cuong T. Nguyen
LLLawrence Le
Lawrence Le
NKNeelambar R. Kaipatur
Neelambar R. Kaipatur
RZRui Zheng
Rui Zheng
ELEdmond H. Lou
Edmond H. Lou
PMPaul W. Major
Paul W. Major