ZnO nanoparticles have been synthesized by precipitation method from Zinc nitrate. The powder was characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, selected-area electron diffraction, UV-vis optical absorption, and photoluminescence spectroscopy analyses. XRD patterns showed that ZnO nanoparticles have hexagonal unit cell structure. SEM and TEM pictures reveal the morphology and particle size of prepared ZnO nanoparticles. The UV-vis absorption spectrum shows an absorption band at 355 nm due to ZnO nanoparticles. The photoluminescence spectrum exhibits two emission peaks one at 392 nm corresponding to band gap excitonic emission and another located at 520 nm due to the presence of singly ionized oxygen vacancies. The synthesis method has potential for application in manufacturing units due to ease processing and more economical reagents.

In this paper, we present and simulates a very sensitive label-free biosensor that uses Si:HfO ₂ ferroelectric junction less tunnel field-effect transistor (FE-JL-TFET) charge/dielectric modulation. For the first time Negative capacitance (NC) behavior is made possible by the ferroelectric gate stacking of Si-doped HfO ₂ in the dual inverted-T cavity with T-shaped channel is used in the biosensor design. Using a sacrificial etching approach, two cavities are formed in the gate-source underlap areas to detect biomolecules such as Lipid (K=3), Carbohydrates (K=5), Plant protein Zein (K=7), Amino acids (K=12) and MDA-MB-231 (Breast Cancer cell, K=22). For both charged and neutral biomolecules the biosensor has shown increased sensitivity. The biomolecules that are neutrally, positively and negatively charged have maximal values of the I _on /I _off ratio that reach as high as 4.65x10 ¹⁰ , 6.24X10 ¹⁰ and 9.47x10 ¹⁰ respectively. It has been noted that the proposed device sensing performance can be greatly enhanced by optimizing the cavity height and length. For Neutral, Negative and Positive charged biomolecules, the proposed biosensor sensitivity has been greatly increased to 8.61X10 ⁴ , 7.93X10 ³ , and 1.05X10 ⁵ respectively. It has shown better sensitivity when compared with other advanced biosensors.