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Chiara Fossati
Department of Movement, Human and Health Sciences, University of Rome “Foro Italico”, Rome, Italy

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Correction
Published: 09 April 2021 in Sports Medicine
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Blair R. Hamilton; Giscard Lima; James Barrett; Leighton Seal; Alexander Kolliari-Turner; Guan Wang; Antonia Karanikolou; Xavier Bigard; Herbert Löllgen; Petra Zupet; Anca Ionescu; Andre Debruyne; Nigel Jones; Karin Vonbank; Federica Fagnani; Chiara Fossati; Maurizio Casasco; Demitri Constantinou; Bernd Wolfarth; David Niederseer; Andrew Bosch; Borja Muniz-Pardos; José Antonio Casajus; Christian Schneider; Sigmund Loland; Michele Verroken; Pedro Manonelles Marqueta; Francisco Arroyo; André Pedrinelli; Konstantinos Natsis; Evert Verhagen; William O. Roberts; José Kawazoe Lazzoli; Rogerio Friedman; Ali Erdogan; Ana V. Cintron; Shu-Hang Patrick Yung; Dina C. Janse van Rensburg; Dimakatso A. Ramagole; Sandra Rozenstoka; Felix Drummond; Theodora Papadopoulou; Paulette Y. O. Kumi; Richard Twycross-Lewis; Joanna Harper; Vasileios Skiadas; Jonathan Shurlock; Kumpei Tanisawa; Jane Seto; Kathryn North; Siddhartha S. Angadi; Maria Jose Martinez-Patiño; Mats Borjesson; Luigi Di Luigi; Michiko Dohi; Jeroen Swart; James Lee John Bilzon; Victoriya Badtieva; Irina Zelenkova; Juergen M. Steinacker; Norbert Bachl; Fabio Pigozzi; Michael Geistlinger; Dimitrios G. Goulis; Fergus Guppy; Nick Webborn; Bulent O. Yildiz; Mike Miller; Patrick Singleton; Yannis P. Pitsiladis. Correction to: Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement. Sports Medicine 2021, 51, 1417 -1418.

AMA Style

Blair R. Hamilton, Giscard Lima, James Barrett, Leighton Seal, Alexander Kolliari-Turner, Guan Wang, Antonia Karanikolou, Xavier Bigard, Herbert Löllgen, Petra Zupet, Anca Ionescu, Andre Debruyne, Nigel Jones, Karin Vonbank, Federica Fagnani, Chiara Fossati, Maurizio Casasco, Demitri Constantinou, Bernd Wolfarth, David Niederseer, Andrew Bosch, Borja Muniz-Pardos, José Antonio Casajus, Christian Schneider, Sigmund Loland, Michele Verroken, Pedro Manonelles Marqueta, Francisco Arroyo, André Pedrinelli, Konstantinos Natsis, Evert Verhagen, William O. Roberts, José Kawazoe Lazzoli, Rogerio Friedman, Ali Erdogan, Ana V. Cintron, Shu-Hang Patrick Yung, Dina C. Janse van Rensburg, Dimakatso A. Ramagole, Sandra Rozenstoka, Felix Drummond, Theodora Papadopoulou, Paulette Y. O. Kumi, Richard Twycross-Lewis, Joanna Harper, Vasileios Skiadas, Jonathan Shurlock, Kumpei Tanisawa, Jane Seto, Kathryn North, Siddhartha S. Angadi, Maria Jose Martinez-Patiño, Mats Borjesson, Luigi Di Luigi, Michiko Dohi, Jeroen Swart, James Lee John Bilzon, Victoriya Badtieva, Irina Zelenkova, Juergen M. Steinacker, Norbert Bachl, Fabio Pigozzi, Michael Geistlinger, Dimitrios G. Goulis, Fergus Guppy, Nick Webborn, Bulent O. Yildiz, Mike Miller, Patrick Singleton, Yannis P. Pitsiladis. Correction to: Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement. Sports Medicine. 2021; 51 (7):1417-1418.

Chicago/Turabian Style

Blair R. Hamilton; Giscard Lima; James Barrett; Leighton Seal; Alexander Kolliari-Turner; Guan Wang; Antonia Karanikolou; Xavier Bigard; Herbert Löllgen; Petra Zupet; Anca Ionescu; Andre Debruyne; Nigel Jones; Karin Vonbank; Federica Fagnani; Chiara Fossati; Maurizio Casasco; Demitri Constantinou; Bernd Wolfarth; David Niederseer; Andrew Bosch; Borja Muniz-Pardos; José Antonio Casajus; Christian Schneider; Sigmund Loland; Michele Verroken; Pedro Manonelles Marqueta; Francisco Arroyo; André Pedrinelli; Konstantinos Natsis; Evert Verhagen; William O. Roberts; José Kawazoe Lazzoli; Rogerio Friedman; Ali Erdogan; Ana V. Cintron; Shu-Hang Patrick Yung; Dina C. Janse van Rensburg; Dimakatso A. Ramagole; Sandra Rozenstoka; Felix Drummond; Theodora Papadopoulou; Paulette Y. O. Kumi; Richard Twycross-Lewis; Joanna Harper; Vasileios Skiadas; Jonathan Shurlock; Kumpei Tanisawa; Jane Seto; Kathryn North; Siddhartha S. Angadi; Maria Jose Martinez-Patiño; Mats Borjesson; Luigi Di Luigi; Michiko Dohi; Jeroen Swart; James Lee John Bilzon; Victoriya Badtieva; Irina Zelenkova; Juergen M. Steinacker; Norbert Bachl; Fabio Pigozzi; Michael Geistlinger; Dimitrios G. Goulis; Fergus Guppy; Nick Webborn; Bulent O. Yildiz; Mike Miller; Patrick Singleton; Yannis P. Pitsiladis. 2021. "Correction to: Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement." Sports Medicine 51, no. 7: 1417-1418.

Review article
Published: 24 March 2021 in Sports Medicine
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Sport is historically designated by the binary categorization of male and female that conflicts with modern society. Sport’s governing bodies should consider reviewing rules determining the eligibility of athletes in the female category as there may be lasting advantages of previously high testosterone concentrations for transwomen athletes and currently high testosterone concentrations in differences in sex development (DSD) athletes. The use of serum testosterone concentrations to regulate the inclusion of such athletes into the elite female category is currently the objective biomarker that is supported by most available scientific literature, but it has limitations due to the lack of sports performance data before, during or after testosterone suppression. Innovative research studies are needed to identify other biomarkers of testosterone sensitivity/responsiveness, including molecular tools to determine the functional status of androgen receptors. The scientific community also needs to conduct longitudinal studies with specific control groups to generate the biological and sports performance data for individual sports to inform the fair inclusion or exclusion of these athletes. Eligibility of each athlete to a sport-specific policy needs to be based on peer-reviewed scientific evidence made available to policymakers from all scientific communities. However, even the most evidence-based regulations are unlikely to eliminate all differences in performance between cisgender women with and without DSD and transwomen athletes. Any remaining advantage held by transwomen or DSD women could be considered as part of the athlete’s unique makeup.

ACS Style

Blair R. Hamilton; Giscard Lima; James Barrett; Leighton Seal; Alexander Kolliari-Turner; Guan Wang; Antonia Karanikolou; Xavier Bigard; Herbert Löllgen; Petra Zupet; Anca Ionescu; Andre Debruyne; Nigel Jones; Karin Vonbank; Federica Fagnani; Chiara Fossati; Maurizio Casasco; Demitri Constantinou; Bernd Wolfarth; David Niederseer; Andrew Bosch; Borja Muniz-Pardos; José Antonio Casajus; Christian Schneider; Sigmund Loland; Michele Verroken; Pedro Manonelles Marqueta; Francisco Arroyo; André Pedrinelli; Konstantinos Natsis; Evert Verhagen; William O. Roberts; José Kawazoe Lazzoli; Rogerio Friedman; Ali Erdogan; Ana V. Cintron; Shu-Hang Patrick Yung; Dina C. Janse van Rensburg; Dimakatso A. Ramagole; Sandra Rozenstoka; Felix Drummond; Theodora Papadopoulou; Paulette Y. O. Kumi; Richard Twycross-Lewis; Joanna Harper; Vasileios Skiadas; Jonathan Shurlock; Kumpei Tanisawa; Jane Seto; Kathryn North; Siddhartha S. Angadi; Maria Jose Martinez-Patiño; Mats Borjesson; Luigi Di Luigi; Michiko Dohi; Jeroen Swart; James Lee John Bilzon; Victoriya Badtieva; Irina Zelenkova; Juergen M. Steinacker; Norbert Bachl; Fabio Pigozzi; Michael Geistlinger; Dimitrios G. Goulis; Fergus Guppy; Nick Webborn; Bulent O. Yildiz; Mike Miller; Patrick Singleton; Yannis P. Pitsiladis. Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement. Sports Medicine 2021, 51, 1401 -1415.

AMA Style

Blair R. Hamilton, Giscard Lima, James Barrett, Leighton Seal, Alexander Kolliari-Turner, Guan Wang, Antonia Karanikolou, Xavier Bigard, Herbert Löllgen, Petra Zupet, Anca Ionescu, Andre Debruyne, Nigel Jones, Karin Vonbank, Federica Fagnani, Chiara Fossati, Maurizio Casasco, Demitri Constantinou, Bernd Wolfarth, David Niederseer, Andrew Bosch, Borja Muniz-Pardos, José Antonio Casajus, Christian Schneider, Sigmund Loland, Michele Verroken, Pedro Manonelles Marqueta, Francisco Arroyo, André Pedrinelli, Konstantinos Natsis, Evert Verhagen, William O. Roberts, José Kawazoe Lazzoli, Rogerio Friedman, Ali Erdogan, Ana V. Cintron, Shu-Hang Patrick Yung, Dina C. Janse van Rensburg, Dimakatso A. Ramagole, Sandra Rozenstoka, Felix Drummond, Theodora Papadopoulou, Paulette Y. O. Kumi, Richard Twycross-Lewis, Joanna Harper, Vasileios Skiadas, Jonathan Shurlock, Kumpei Tanisawa, Jane Seto, Kathryn North, Siddhartha S. Angadi, Maria Jose Martinez-Patiño, Mats Borjesson, Luigi Di Luigi, Michiko Dohi, Jeroen Swart, James Lee John Bilzon, Victoriya Badtieva, Irina Zelenkova, Juergen M. Steinacker, Norbert Bachl, Fabio Pigozzi, Michael Geistlinger, Dimitrios G. Goulis, Fergus Guppy, Nick Webborn, Bulent O. Yildiz, Mike Miller, Patrick Singleton, Yannis P. Pitsiladis. Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement. Sports Medicine. 2021; 51 (7):1401-1415.

Chicago/Turabian Style

Blair R. Hamilton; Giscard Lima; James Barrett; Leighton Seal; Alexander Kolliari-Turner; Guan Wang; Antonia Karanikolou; Xavier Bigard; Herbert Löllgen; Petra Zupet; Anca Ionescu; Andre Debruyne; Nigel Jones; Karin Vonbank; Federica Fagnani; Chiara Fossati; Maurizio Casasco; Demitri Constantinou; Bernd Wolfarth; David Niederseer; Andrew Bosch; Borja Muniz-Pardos; José Antonio Casajus; Christian Schneider; Sigmund Loland; Michele Verroken; Pedro Manonelles Marqueta; Francisco Arroyo; André Pedrinelli; Konstantinos Natsis; Evert Verhagen; William O. Roberts; José Kawazoe Lazzoli; Rogerio Friedman; Ali Erdogan; Ana V. Cintron; Shu-Hang Patrick Yung; Dina C. Janse van Rensburg; Dimakatso A. Ramagole; Sandra Rozenstoka; Felix Drummond; Theodora Papadopoulou; Paulette Y. O. Kumi; Richard Twycross-Lewis; Joanna Harper; Vasileios Skiadas; Jonathan Shurlock; Kumpei Tanisawa; Jane Seto; Kathryn North; Siddhartha S. Angadi; Maria Jose Martinez-Patiño; Mats Borjesson; Luigi Di Luigi; Michiko Dohi; Jeroen Swart; James Lee John Bilzon; Victoriya Badtieva; Irina Zelenkova; Juergen M. Steinacker; Norbert Bachl; Fabio Pigozzi; Michael Geistlinger; Dimitrios G. Goulis; Fergus Guppy; Nick Webborn; Bulent O. Yildiz; Mike Miller; Patrick Singleton; Yannis P. Pitsiladis. 2021. "Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement." Sports Medicine 51, no. 7: 1401-1415.

Journal article
Published: 24 February 2021 in International Journal of Environmental Research and Public Health
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Governments have restricted public life during the COVID-19 pandemic, inter alia closing sports facilities and gyms. As regular exercise is essential for health, this study examined the effect of pandemic-related confinements on physical activity (PA) levels. A multinational survey was performed in 14 countries. Times spent in moderate-to-vigorous physical activity (MVPA) as well as in vigorous physical activity only (VPA) were assessed using the Nordic Physical Activity Questionnaire (short form). Data were obtained for leisure and occupational PA pre- and during restrictions. Compliance with PA guidelines was calculated based on the recommendations of the World Health Organization (WHO). In total, n = 13,503 respondents (39 ± 15 years, 59% females) were surveyed. Compared to pre-restrictions, overall self-reported PA declined by 41% (MVPA) and 42.2% (VPA). Reductions were higher for occupational vs. leisure time, young and old vs. middle-aged persons, previously more active vs. less active individuals, but similar between men and women. Compared to pre-pandemic, compliance with WHO guidelines decreased from 80.9% (95% CI: 80.3–81.7) to 62.5% (95% CI: 61.6–63.3). Results suggest PA levels have substantially decreased globally during the COVID-19 pandemic. Key stakeholders should consider strategies to mitigate loss in PA in order to preserve health during the pandemic.

ACS Style

Jan Wilke; Lisa Mohr; Adam Tenforde; Pascal Edouard; Chiara Fossati; Marcela González-Gross; Celso Sánchez Ramírez; Fernando Laiño; Benedict Tan; Julian Pillay; Fabio Pigozzi; David Jimenez-Pavon; Bernhard Novak; Johannes Jaunig; Mandy Zhang; Mireille van Poppel; Christoph Heidt; Steffen Willwacher; Gustavo Yuki; Daniel Lieberman; Lutz Vogt; Evert Verhagen; Luiz Hespanhol; Karsten Hollander. A Pandemic within the Pandemic? Physical Activity Levels Substantially Decreased in Countries Affected by COVID-19. International Journal of Environmental Research and Public Health 2021, 18, 2235 .

AMA Style

Jan Wilke, Lisa Mohr, Adam Tenforde, Pascal Edouard, Chiara Fossati, Marcela González-Gross, Celso Sánchez Ramírez, Fernando Laiño, Benedict Tan, Julian Pillay, Fabio Pigozzi, David Jimenez-Pavon, Bernhard Novak, Johannes Jaunig, Mandy Zhang, Mireille van Poppel, Christoph Heidt, Steffen Willwacher, Gustavo Yuki, Daniel Lieberman, Lutz Vogt, Evert Verhagen, Luiz Hespanhol, Karsten Hollander. A Pandemic within the Pandemic? Physical Activity Levels Substantially Decreased in Countries Affected by COVID-19. International Journal of Environmental Research and Public Health. 2021; 18 (5):2235.

Chicago/Turabian Style

Jan Wilke; Lisa Mohr; Adam Tenforde; Pascal Edouard; Chiara Fossati; Marcela González-Gross; Celso Sánchez Ramírez; Fernando Laiño; Benedict Tan; Julian Pillay; Fabio Pigozzi; David Jimenez-Pavon; Bernhard Novak; Johannes Jaunig; Mandy Zhang; Mireille van Poppel; Christoph Heidt; Steffen Willwacher; Gustavo Yuki; Daniel Lieberman; Lutz Vogt; Evert Verhagen; Luiz Hespanhol; Karsten Hollander. 2021. "A Pandemic within the Pandemic? Physical Activity Levels Substantially Decreased in Countries Affected by COVID-19." International Journal of Environmental Research and Public Health 18, no. 5: 2235.

Journal article
Published: 22 December 2020 in Nutrients
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The revised European consensus defined sarcopenia as a progressive and generalized skeletal muscle disorder that is associated with an increased likelihood of adverse outcomes including falls, fractures, physical disability and mortality. The aim of this study was to determine the prevalence of sarcopenia and analyse the influence of diet, physical activity (PA) and obesity index as risk factors of each criteria of sarcopenia. A total of 629 European middle-aged and older adults were enrolled in this cross-sectional study. Anthropometrics were assessed. Self-reported PA and adherence to the Mediterranean diet were evaluated with the Global Physical Activity Questionnaire (GPAQ) and Prevention with Mediterranean Diet questionnaire (PREDIMED), respectively. The functional assessment included handgrip strength, lower body muscle strength, gait speed and agility/dynamic balance. Of the participants, 4.84% to 7.33% showed probable sarcopenia. Sarcopenia was confirmed in 1.16% to 2.93% of participants. Severe sarcopenia was shown by 0.86% to 1.49% of participants. Male; age group ≤65 years; lower body mass index (BMI); high levels of vigorous PA; and the consumption of more than one portion per day of red meat, hamburgers, sausages or cold cuts and/or preferential consumption of rabbit, chicken or turkey instead of beef, pork, hamburgers or sausages (OR = 0.126–0.454; all p < 0.013) resulted as protective factors, and more time of sedentary time (OR = 1.608–2.368; p = 0.032–0.041) resulted as a risk factor for some criteria of sarcopenia. In conclusion, age, diet, PA, and obesity can affect the risk of having low muscle strength, low muscle mass or low functional performance, factors connected with sarcopenia.

ACS Style

Pablo Marcos-Pardo; Noelia González-Gálvez; Abraham López-Vivancos; Alejandro Espeso-García; Luis Martínez-Aranda; Gemma Gea-García; Francisco Orquín-Castrillón; Ana Carbonell-Baeza; José Jiménez-García; Daniel Velázquez-Díaz; Cristina Cadenas-Sanchez; Emanuele Isidori; Chiara Fossati; Fabio Pigozzi; Lorenzo Rum; Catherine Norton; Audrey Tierney; Ilvis Äbelkalns; Agita Klempere-Sipjagina; Juris Porozovs; Heikki Hannola; Niko Niemisalo; Leo Hokka; David Jiménez-Pavón; Raquel Vaquero-Cristóbal. Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study. Nutrients 2020, 13, 8 .

AMA Style

Pablo Marcos-Pardo, Noelia González-Gálvez, Abraham López-Vivancos, Alejandro Espeso-García, Luis Martínez-Aranda, Gemma Gea-García, Francisco Orquín-Castrillón, Ana Carbonell-Baeza, José Jiménez-García, Daniel Velázquez-Díaz, Cristina Cadenas-Sanchez, Emanuele Isidori, Chiara Fossati, Fabio Pigozzi, Lorenzo Rum, Catherine Norton, Audrey Tierney, Ilvis Äbelkalns, Agita Klempere-Sipjagina, Juris Porozovs, Heikki Hannola, Niko Niemisalo, Leo Hokka, David Jiménez-Pavón, Raquel Vaquero-Cristóbal. Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study. Nutrients. 2020; 13 (1):8.

Chicago/Turabian Style

Pablo Marcos-Pardo; Noelia González-Gálvez; Abraham López-Vivancos; Alejandro Espeso-García; Luis Martínez-Aranda; Gemma Gea-García; Francisco Orquín-Castrillón; Ana Carbonell-Baeza; José Jiménez-García; Daniel Velázquez-Díaz; Cristina Cadenas-Sanchez; Emanuele Isidori; Chiara Fossati; Fabio Pigozzi; Lorenzo Rum; Catherine Norton; Audrey Tierney; Ilvis Äbelkalns; Agita Klempere-Sipjagina; Juris Porozovs; Heikki Hannola; Niko Niemisalo; Leo Hokka; David Jiménez-Pavón; Raquel Vaquero-Cristóbal. 2020. "Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study." Nutrients 13, no. 1: 8.

Letter to the editor
Published: 08 December 2020 in Sports Medicine
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ACS Style

Blair R. Hamilton; Maria Jose Martinez-Patiño; James Barrett; Leighton Seal; Ross Tucker; Theodora Papadopoulou; Xavier Bigard; Alexander Kolliari-Turner; Herbert Löllgen; Petra Zupet; Anca Ionescu; Andre Debruyne; Nigel Jones; Juergen M. Steinacker; Karin Vonbank; Giscard Lima; Federica Fagnani; Chiara Fossati; Luigi Di Luigi; Fabio Pigozzi; Maurizio Casasco; Michael Geistlinger; Bernd Wolfarth; Jane T. Seto; Norbert Bachl; Richard Twycross-Lewis; David Niederseer; Andrew Bosch; Jeroen Swart; Demitri Constantinou; Borja Muniz-Pardos; José Antonio Casajus; Victoriya Badtieva; Irina Zelenkova; James L. J. Bilzon; Michiko Dohi; Christian Schneider; Sigmund Loland; Michele Verroken; Pedro Manonelles Marqueta; Francisco Arroyo; André Pedrinelli; Konstantinos Natsis; Evert Verhagen; William O. Roberts; José Kawazoe Lazzoli; Rogerio Friedman; Ali Erdogan; Ana V. Cintron; Shu-Hang Patrick Yung; Dina C. Janse van Rensburg; Dimakatso A. Ramagole; Sandra Rozenstoka; Felix Drummond; Nick Webborn; Fergus M. Guppy; Yannis P. Pitsiladis. Response to the United Nations Human Rights Council’s Report on Race and Gender Discrimination in Sport: An Expression of Concern and a Call to Prioritise Research. Sports Medicine 2020, 51, 839 -842.

AMA Style

Blair R. Hamilton, Maria Jose Martinez-Patiño, James Barrett, Leighton Seal, Ross Tucker, Theodora Papadopoulou, Xavier Bigard, Alexander Kolliari-Turner, Herbert Löllgen, Petra Zupet, Anca Ionescu, Andre Debruyne, Nigel Jones, Juergen M. Steinacker, Karin Vonbank, Giscard Lima, Federica Fagnani, Chiara Fossati, Luigi Di Luigi, Fabio Pigozzi, Maurizio Casasco, Michael Geistlinger, Bernd Wolfarth, Jane T. Seto, Norbert Bachl, Richard Twycross-Lewis, David Niederseer, Andrew Bosch, Jeroen Swart, Demitri Constantinou, Borja Muniz-Pardos, José Antonio Casajus, Victoriya Badtieva, Irina Zelenkova, James L. J. Bilzon, Michiko Dohi, Christian Schneider, Sigmund Loland, Michele Verroken, Pedro Manonelles Marqueta, Francisco Arroyo, André Pedrinelli, Konstantinos Natsis, Evert Verhagen, William O. Roberts, José Kawazoe Lazzoli, Rogerio Friedman, Ali Erdogan, Ana V. Cintron, Shu-Hang Patrick Yung, Dina C. Janse van Rensburg, Dimakatso A. Ramagole, Sandra Rozenstoka, Felix Drummond, Nick Webborn, Fergus M. Guppy, Yannis P. Pitsiladis. Response to the United Nations Human Rights Council’s Report on Race and Gender Discrimination in Sport: An Expression of Concern and a Call to Prioritise Research. Sports Medicine. 2020; 51 (4):839-842.

Chicago/Turabian Style

Blair R. Hamilton; Maria Jose Martinez-Patiño; James Barrett; Leighton Seal; Ross Tucker; Theodora Papadopoulou; Xavier Bigard; Alexander Kolliari-Turner; Herbert Löllgen; Petra Zupet; Anca Ionescu; Andre Debruyne; Nigel Jones; Juergen M. Steinacker; Karin Vonbank; Giscard Lima; Federica Fagnani; Chiara Fossati; Luigi Di Luigi; Fabio Pigozzi; Maurizio Casasco; Michael Geistlinger; Bernd Wolfarth; Jane T. Seto; Norbert Bachl; Richard Twycross-Lewis; David Niederseer; Andrew Bosch; Jeroen Swart; Demitri Constantinou; Borja Muniz-Pardos; José Antonio Casajus; Victoriya Badtieva; Irina Zelenkova; James L. J. Bilzon; Michiko Dohi; Christian Schneider; Sigmund Loland; Michele Verroken; Pedro Manonelles Marqueta; Francisco Arroyo; André Pedrinelli; Konstantinos Natsis; Evert Verhagen; William O. Roberts; José Kawazoe Lazzoli; Rogerio Friedman; Ali Erdogan; Ana V. Cintron; Shu-Hang Patrick Yung; Dina C. Janse van Rensburg; Dimakatso A. Ramagole; Sandra Rozenstoka; Felix Drummond; Nick Webborn; Fergus M. Guppy; Yannis P. Pitsiladis. 2020. "Response to the United Nations Human Rights Council’s Report on Race and Gender Discrimination in Sport: An Expression of Concern and a Call to Prioritise Research." Sports Medicine 51, no. 4: 839-842.

Brief report
Published: 07 September 2020 in International Journal of Environmental Research and Public Health
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Confinement measures during the COVID-19 pandemic have caused substantial reductions in global physical activity (PA) levels. In view of the manifold health benefits of PA, the development of interventions counteracting this trend is paramount. Our survey with 15,261 participants (38 ± 15 years, 58.5% females) examined preferences towards digital home exercise programs in 14 countries affected by COVID-19. More than two-thirds of the sample (68.4%, n = 10,433) indicated being interested in home exercise, and most participants were willing to work out at least three times per week (89.3%, n = 9328). Binary logistic regression revealed that female sex, working part-time, younger age, and being registered in a gym were associated with willingness to exercise. Flexibility (71.1%, n = 7377), resistance (68.6%, n = 7116), and endurance training (62.4%, n = 6478) were the most preferred types of exercise. Our results may guide health providers in developing individually tailored PA interventions during the current and future pandemics.

ACS Style

Jan Wilke; Lisa Mohr; Adam Tenforde; Pascal Edouard; Chiara Fossati; Marcela González-Gross; Celso Ramirez; Fernando Laiño; Benedict Tan; Julian Pillay; Fabio Pigozzi; David Jimenez-Pavon; Bernhard Novak; David Url; Mandy Zhang; Mireille Poppel; Christoph Heidt; Steffen Willwacher; Lutz Vogt; Evert Verhagen; Karsten Hollander; Luiz Hespanhol; Gustavo Yuki. Restrictercise! Preferences Regarding Digital Home Training Programs during Confinements Associated with the COVID-19 Pandemic. International Journal of Environmental Research and Public Health 2020, 17, 6515 .

AMA Style

Jan Wilke, Lisa Mohr, Adam Tenforde, Pascal Edouard, Chiara Fossati, Marcela González-Gross, Celso Ramirez, Fernando Laiño, Benedict Tan, Julian Pillay, Fabio Pigozzi, David Jimenez-Pavon, Bernhard Novak, David Url, Mandy Zhang, Mireille Poppel, Christoph Heidt, Steffen Willwacher, Lutz Vogt, Evert Verhagen, Karsten Hollander, Luiz Hespanhol, Gustavo Yuki. Restrictercise! Preferences Regarding Digital Home Training Programs during Confinements Associated with the COVID-19 Pandemic. International Journal of Environmental Research and Public Health. 2020; 17 (18):6515.

Chicago/Turabian Style

Jan Wilke; Lisa Mohr; Adam Tenforde; Pascal Edouard; Chiara Fossati; Marcela González-Gross; Celso Ramirez; Fernando Laiño; Benedict Tan; Julian Pillay; Fabio Pigozzi; David Jimenez-Pavon; Bernhard Novak; David Url; Mandy Zhang; Mireille Poppel; Christoph Heidt; Steffen Willwacher; Lutz Vogt; Evert Verhagen; Karsten Hollander; Luiz Hespanhol; Gustavo Yuki. 2020. "Restrictercise! Preferences Regarding Digital Home Training Programs during Confinements Associated with the COVID-19 Pandemic." International Journal of Environmental Research and Public Health 17, no. 18: 6515.

Review
Published: 11 August 2020 in Journal of Clinical Medicine
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The aims of this systematic review and meta-analysis were to evaluate the effects of physical exercise on static and dynamic balance in the elderly population, and to analyze the number of falls and fallers. A systematic literature search was conducted using PubMed–Medline, Cochrane Central, and Google Scholar to select randomized clinical trials that analyzed the role of exercise on balance and fall rate in patients aged 65 or older. Sixteen articles were included in this review. Applying the Cochrane risk-of-bias tool, three studies were determined to be at low risk of bias, nine at unclear risk of bias, and four at high risk of bias. The meta-analysis showed improvements in dynamic balance (p = 0.008), static balance (p = 0.01), participants’ fear of falling (p = 0.10), balance confidence (p = 0.04), quality of life (p = 0.08), and physical performance (p = 0.30) in patients who underwent physical exercise compared to controls. The analysis of the total numbers of falls showed a decreased likelihood of falls in patients who participated in exercise programs (p = 0.0008). Finally, the number of patients who fell at least once was significantly reduced in the intervention group (p = 0.02). Physical exercise is an effective treatment to improve balance and reduce fall rates in the elderly.

ACS Style

Giuseppe Francesco Papalia; Rocco Papalia; Lorenzo Alirio Diaz Balzani; Guglielmo Torre; Biagio Zampogna; Sebastiano Vasta; Chiara Fossati; Anna Maria Alifano; Vincenzo Denaro. The Effects of Physical Exercise on Balance and Prevention of Falls in Older People: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine 2020, 9, 2595 .

AMA Style

Giuseppe Francesco Papalia, Rocco Papalia, Lorenzo Alirio Diaz Balzani, Guglielmo Torre, Biagio Zampogna, Sebastiano Vasta, Chiara Fossati, Anna Maria Alifano, Vincenzo Denaro. The Effects of Physical Exercise on Balance and Prevention of Falls in Older People: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2020; 9 (8):2595.

Chicago/Turabian Style

Giuseppe Francesco Papalia; Rocco Papalia; Lorenzo Alirio Diaz Balzani; Guglielmo Torre; Biagio Zampogna; Sebastiano Vasta; Chiara Fossati; Anna Maria Alifano; Vincenzo Denaro. 2020. "The Effects of Physical Exercise on Balance and Prevention of Falls in Older People: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 9, no. 8: 2595.

Review
Published: 22 May 2020 in Journal of Clinical Medicine
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The aim of this systematic review and meta-analysis was to evaluate the rate of return to sport in elderly patients who underwent anatomic (ATSA) and reverse (RTSA) total shoulder arthroplasty, to assess postoperative pain and functional outcomes and to give an overview of postoperative rehabilitation protocols. A systematic search in Pubmed-Medline, Cochrane Library, and Google Scholar was carried out to identify eligible randomized clinical trials, observational studies, or case series that evaluated the rate of return to sport after RTSA or ATSA. Six retrospective studies, five case series, and one prospective cohort study were included in this review. The overall rate of return to sport was 82% (95% CI 0.76–0.88, p < 0.01). Patients undergoing ATSA returned at a higher rate (90%) (95% CI 0.80–0.99, p < 0.01) compared to RTSA (77%) (95% CI 0.69–0.85, p < 0.01). Moreover, the results showed that patients returned to sport at the same or a higher level in 75% of cases. Swimming had the highest rate of return (84%), followed by fitness (77%), golf (77%), and tennis (69%). Thus, RTSA and ATSA are effective to guarantee a significative rate of return to sport in elderly patients. A slightly higher rate was found for the anatomic implant.

ACS Style

Rocco Papalia; Mauro Ciuffreda; Erika Albo; Chiara De Andreis; Lorenzo Alirio Diaz Balzani; Anna Maria Alifano; Chiara Fossati; Andrea Macaluso; Riccardo Borzuola; Antonio De Vincentis; Vincenzo Denaro. Return to Sport after Anatomic and Reverse Total Shoulder Arthroplasty in Elderly Patients: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine 2020, 9, 1576 .

AMA Style

Rocco Papalia, Mauro Ciuffreda, Erika Albo, Chiara De Andreis, Lorenzo Alirio Diaz Balzani, Anna Maria Alifano, Chiara Fossati, Andrea Macaluso, Riccardo Borzuola, Antonio De Vincentis, Vincenzo Denaro. Return to Sport after Anatomic and Reverse Total Shoulder Arthroplasty in Elderly Patients: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2020; 9 (5):1576.

Chicago/Turabian Style

Rocco Papalia; Mauro Ciuffreda; Erika Albo; Chiara De Andreis; Lorenzo Alirio Diaz Balzani; Anna Maria Alifano; Chiara Fossati; Andrea Macaluso; Riccardo Borzuola; Antonio De Vincentis; Vincenzo Denaro. 2020. "Return to Sport after Anatomic and Reverse Total Shoulder Arthroplasty in Elderly Patients: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 9, no. 5: 1576.

Review
Published: 09 May 2020 in Journal of Clinical Medicine
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Hip and knee replacement is an effective treatment for symptomatic, end-stage hip and knee osteoarthritis, aiming to relieve pain and restore joint function. Several postoperative rehabilitation protocols and physical activities are proposed in routine clinical practice. However, their effect on clinical outcome and implant revision in patients undergoing joint replacement is still unclear. A systematic review of the literature was performed through a comprehensive search on online databases including Pubmed-Medline, Cochrane central, and Google scholar. We included all the available studies on postoperative physical activity and rehabilitation protocols after total knee and total hip arthroplasty in patients older than 65 years. The primary endpoint was to evaluate the effect of physical activity and rehabilitation on clinical outcome; the secondary outcome was to determine the effect on patients’ quality of life (QoL) and implant survival. Although the heterogeneity of the rehabilitation protocols and outcome measures did not allow to draw definitive conclusions, most studies suggested that aquatic therapy, ergometer cycling, and fast-track protocols have a beneficial effect on muscle strength, gait speed, and main clinical scores after total hip arthroplasty. Similarly, enhanced rehabilitation protocols produced an improvement in primary and secondary outcomes after total knee arthroplasty.

ACS Style

Rocco Papalia; Stefano Campi; Ferruccio Vorini; Biagio Zampogna; Sebastiano Vasta; Giuseppe Papalia; Chiara Fossati; Guglielmo Torre; Vincenzo Denaro. The Role of Physical Activity and Rehabilitation Following Hip and Knee Arthroplasty in the Elderly. Journal of Clinical Medicine 2020, 9, 1401 .

AMA Style

Rocco Papalia, Stefano Campi, Ferruccio Vorini, Biagio Zampogna, Sebastiano Vasta, Giuseppe Papalia, Chiara Fossati, Guglielmo Torre, Vincenzo Denaro. The Role of Physical Activity and Rehabilitation Following Hip and Knee Arthroplasty in the Elderly. Journal of Clinical Medicine. 2020; 9 (5):1401.

Chicago/Turabian Style

Rocco Papalia; Stefano Campi; Ferruccio Vorini; Biagio Zampogna; Sebastiano Vasta; Giuseppe Papalia; Chiara Fossati; Guglielmo Torre; Vincenzo Denaro. 2020. "The Role of Physical Activity and Rehabilitation Following Hip and Knee Arthroplasty in the Elderly." Journal of Clinical Medicine 9, no. 5: 1401.

Review
Published: 18 April 2020 in Journal of Clinical Medicine
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The aim of this systematic review and meta-analysis is to determine the role of physical activity as a conservative treatment for older people with knee or hip osteoarthritis. The effect on pain, physical function, stiffness, quality of life, and dynamic balance of Aquatic Exercise, Land-based Exercise, and Sports were compared in a specific population composed of osteoarthritic patients aged 65 or over. A systematic search using Pubmed-Medline, Google Scholar, and the Cochrane Library was carried out to select randomized clinical trials, observational studies, or case series that evaluated outcome measures after physical activity. Twenty randomized controlled trials (RCTs) and two case series were included in this review. Four trials were at low risk of bias (A), 12 at unclear risk of bias (B), and four at high risk of bias (C). Compared to controls, Aquatic Exercise, Land-based Exercise, Tai Chi, and Yoga showed a small to high effect for improving pain, physical function, quality of life, and stiffness. Active exercise and sport are effective to improve pain and physical function in elderly people with osteoarthritis. Nevertheless, further studies are required to validate the use of land-based exercise, aquatic exercise, or sport to treat the symptoms of older adults that suffer from knee and hip osteoarthritis.

ACS Style

Biagio Zampogna; Rocco Papalia; Giuseppe Francesco Papalia; Stefano Campi; Sebastiano Vasta; Ferruccio Vorini; Chiara Fossati; Guglielmo Torre; Vincenzo Denaro. The Role of Physical Activity as Conservative Treatment for Hip and Knee Osteoarthritis in Older People: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine 2020, 9, 1167 .

AMA Style

Biagio Zampogna, Rocco Papalia, Giuseppe Francesco Papalia, Stefano Campi, Sebastiano Vasta, Ferruccio Vorini, Chiara Fossati, Guglielmo Torre, Vincenzo Denaro. The Role of Physical Activity as Conservative Treatment for Hip and Knee Osteoarthritis in Older People: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2020; 9 (4):1167.

Chicago/Turabian Style

Biagio Zampogna; Rocco Papalia; Giuseppe Francesco Papalia; Stefano Campi; Sebastiano Vasta; Ferruccio Vorini; Chiara Fossati; Guglielmo Torre; Vincenzo Denaro. 2020. "The Role of Physical Activity as Conservative Treatment for Hip and Knee Osteoarthritis in Older People: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 9, no. 4: 1167.

Review
Published: 13 April 2020 in Journal of Clinical Medicine
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In the scientific landscape, there is a growing interest in defining the role of several biomolecules and humoral indicators of the aging process and in the modifications of these biomarkers induced by physical activity and exercise. The main aim of the present narrative review is to collect the available evidence on the biohumoral indicators that could be modified by physical activity (PA) in the elderly. Online databases including Pubmed, Web of science (Medline), and Scopus were searched for relevant articles published in the last five years in English. Keywords and combination of these used for the search were the following: “biological”, “indicators”, “markers”, “physical”, “activity”, and “elderly”. Thirty-four papers were analyzed for inclusion. Twenty-nine studies were included and divided into four categories: cardiovascular (CV) biomarkers, metabolic biomarkers, inflammatory markers-oxidative stress molecules, and other markers. There are many distinct biomarkers influenced by PA in the elderly, with promising results concerning the metabolic and CV indexes, as a growing number of studies demonstrate the role of PA on improving parameters related to heart function and CV risk like atherogenic lipid profile. Furthermore, it is also a verified hypothesis that PA is able to modify the inflammatory status of the subject by decreasing the levels of pro-inflammatory cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α). PA seems also to be able to have a direct effect on the immune system. There is a strong evidence of a positive effect of PA on the health of elderly people that could be evidenced and “quantified” by the modifications of the levels of several biohumoral indicators.

ACS Style

Chiara Fossati; Guglielmo Torre; Paolo Borrione; Arrigo Giombini; Federica Fagnani; Matteo Turchetta; Erika Albo; Maurizio Casasco; Attilio Parisi; Fabio Pigozzi. Biohumoral Indicators Influenced by Physical Activity in the Elderly. Journal of Clinical Medicine 2020, 9, 1115 .

AMA Style

Chiara Fossati, Guglielmo Torre, Paolo Borrione, Arrigo Giombini, Federica Fagnani, Matteo Turchetta, Erika Albo, Maurizio Casasco, Attilio Parisi, Fabio Pigozzi. Biohumoral Indicators Influenced by Physical Activity in the Elderly. Journal of Clinical Medicine. 2020; 9 (4):1115.

Chicago/Turabian Style

Chiara Fossati; Guglielmo Torre; Paolo Borrione; Arrigo Giombini; Federica Fagnani; Matteo Turchetta; Erika Albo; Maurizio Casasco; Attilio Parisi; Fabio Pigozzi. 2020. "Biohumoral Indicators Influenced by Physical Activity in the Elderly." Journal of Clinical Medicine 9, no. 4: 1115.

Review
Published: 31 March 2020 in Journal of Clinical Medicine
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Total hip arthroplasty (THA) and total knee arthroplasty (TKA) represent two of the most common procedures in orthopedic surgery. The growing need to avoid physical impairment in elderly patients undergoing this kind of surgery puts the focus on the possibility to undertake a preoperative physical activity program to improve their fit and physical health at the time of surgery. A systematic review has been carried out with online databases including PubMed-Medline, Cochrane Central and Google Scholar. The aim was to retrieve available evidence concerning preoperative physical activity and exercise, before total knee or total hip arthroplasty in patients older than 65 years, and to clarify the role of this practice in improving postoperative outcomes. Results of the present systematic analysis showed that, for TKA, most of the studies demonstrated a comparable trend of postoperative improvement of Visual Analogue Scale (VAS), range of movement (ROM) and functional scores, and those of quality of life. There is insufficient evidence in the literature to draw final conclusions on the topic. Prehabilitation for patients undergoing TKA leads to shorter length of stay but not to an enhanced postoperative recovery. Concerning THA, although currently available data showed better outcomes in patients who underwent prehabilitation programs, there is a lack of robust evidence with appropriate methodology.

ACS Style

Sebastiano Vasta; Rocco Papalia; Guglielmo Torre; Ferruccio Vorini; Giuseppe Papalia; Biagio Zampogna; Chiara Fossati; Marco Bravi; Stefano Campi; Vincenzo Denaro. The Influence of Preoperative Physical Activity on Postoperative Outcomes of Knee and Hip Arthroplasty Surgery in the Elderly: A Systematic Review. Journal of Clinical Medicine 2020, 9, 969 .

AMA Style

Sebastiano Vasta, Rocco Papalia, Guglielmo Torre, Ferruccio Vorini, Giuseppe Papalia, Biagio Zampogna, Chiara Fossati, Marco Bravi, Stefano Campi, Vincenzo Denaro. The Influence of Preoperative Physical Activity on Postoperative Outcomes of Knee and Hip Arthroplasty Surgery in the Elderly: A Systematic Review. Journal of Clinical Medicine. 2020; 9 (4):969.

Chicago/Turabian Style

Sebastiano Vasta; Rocco Papalia; Guglielmo Torre; Ferruccio Vorini; Giuseppe Papalia; Biagio Zampogna; Chiara Fossati; Marco Bravi; Stefano Campi; Vincenzo Denaro. 2020. "The Influence of Preoperative Physical Activity on Postoperative Outcomes of Knee and Hip Arthroplasty Surgery in the Elderly: A Systematic Review." Journal of Clinical Medicine 9, no. 4: 969.

Review
Published: 09 March 2020 in Journal of Clinical Medicine
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Ageing is accompanied by a severe muscle function decline presumably caused by structural and functional adaptations at the central and peripheral level. Although researchers have reported an extensive analysis of the alterations involving muscle intrinsic properties, only a limited number of studies have recognised the importance of the central nervous system, and its reorganisation, on neuromuscular decline. Neural changes, such as degeneration of the human cortex and function of spinal circuitry, as well as the remodelling of the neuromuscular junction and motor units, appear to play a fundamental role in muscle quality decay and culminate with considerable impairments in voluntary activation and motor performance. Modern diagnostic techniques have provided indisputable evidence of a structural and morphological rearrangement of the central nervous system during ageing. Nevertheless, there is no clear insight on how such structural reorganisation contributes to the age-related functional decline and whether it is a result of a neural malfunction or serves as a compensatory mechanism to preserve motor control and performance in the elderly population. Combining leading-edge techniques such as high-density surface electromyography (EMG) and improved diagnostic procedures such as functional magnetic resonance imaging (fMRI) or high-resolution electroencephalography (EEG) could be essential to address the unresolved controversies and achieve an extensive understanding of the relationship between neural adaptations and muscle decline.

ACS Style

Riccardo Borzuola; Arrigo Giombini; Guglielmo Torre; Stefano Campi; Erika Albo; Marco Bravi; Paolo Borrione; Chiara Fossati; Andrea Macaluso. Central and Peripheral Neuromuscular Adaptations to Ageing. Journal of Clinical Medicine 2020, 9, 741 .

AMA Style

Riccardo Borzuola, Arrigo Giombini, Guglielmo Torre, Stefano Campi, Erika Albo, Marco Bravi, Paolo Borrione, Chiara Fossati, Andrea Macaluso. Central and Peripheral Neuromuscular Adaptations to Ageing. Journal of Clinical Medicine. 2020; 9 (3):741.

Chicago/Turabian Style

Riccardo Borzuola; Arrigo Giombini; Guglielmo Torre; Stefano Campi; Erika Albo; Marco Bravi; Paolo Borrione; Chiara Fossati; Andrea Macaluso. 2020. "Central and Peripheral Neuromuscular Adaptations to Ageing." Journal of Clinical Medicine 9, no. 3: 741.

Journal article
Published: 12 September 2019 in British Journal of Clinical Pharmacology
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While several generic preparations of levodopa/carbidopa and levodopa/benserazide (LBD) are currently available, pharmacokinetic (PK) equivalence and therapeutic equivalence studies with levodopa generics are not available in Italy. Lack of data on generic formulations is a critical factor for their limited use in this country and often lead patients to refuse the generic version of the branded drug. An experimental, 2-centre, randomized, double-blind, 2-sequence, noninferiority cross-over study was designed to evaluate both the PK equivalence and clinical equivalence of multiple doses of the generic preparation of LDB, Teva Italia, compared to the originator (Madopar). Forty-three out-patients with a diagnosis of idiopathic Parkinson's disease on LDB, were recruited and randomly assigned to 1 of 2 study sequences: generic-originator or originator-generic. Clinical evaluations were performed at the end of each study period. A PK study with an LDB fixed dose (100 + 25 mg) was performed in a subpopulation of 14 subjects. Clinical data showed a reduction of 0.49 and 1.54 in the mean UPDRS III scores for the LDB and the originator, respectively. The 95% CIs [-2.21: 0.11] of the mean difference original vs LDB are smaller than the clinically significant difference of 3 UPDRS III points, supporting the conclusion that the treatment with LDB is not inferior to the originator. No statistically significant differences were found with respect to area under the curve to last dose, half-life, maximum concentration, time to maximum concentration and last observed concentration. These findings prove the therapeutic clinical equivalence as well the PK equivalence of the generic LDB and the originator (Madopar).

ACS Style

Margherita Torti; Jhessica Alessandroni; Daniele Bravi; Miriam Casali; Paola Grassini; Chiara Fossati; Cristiano Ialongo; Marco Onofrj; Fabiana Giada Radicati; Laura Vacca; Stefano Bonassi; Fabrizio Stocchi. Clinical and pharmacokinetics equivalence of multiple doses of levodopa benserazide generic formulation vs the originator (Madopar). British Journal of Clinical Pharmacology 2019, 85, 2605 -2613.

AMA Style

Margherita Torti, Jhessica Alessandroni, Daniele Bravi, Miriam Casali, Paola Grassini, Chiara Fossati, Cristiano Ialongo, Marco Onofrj, Fabiana Giada Radicati, Laura Vacca, Stefano Bonassi, Fabrizio Stocchi. Clinical and pharmacokinetics equivalence of multiple doses of levodopa benserazide generic formulation vs the originator (Madopar). British Journal of Clinical Pharmacology. 2019; 85 (11):2605-2613.

Chicago/Turabian Style

Margherita Torti; Jhessica Alessandroni; Daniele Bravi; Miriam Casali; Paola Grassini; Chiara Fossati; Cristiano Ialongo; Marco Onofrj; Fabiana Giada Radicati; Laura Vacca; Stefano Bonassi; Fabrizio Stocchi. 2019. "Clinical and pharmacokinetics equivalence of multiple doses of levodopa benserazide generic formulation vs the originator (Madopar)." British Journal of Clinical Pharmacology 85, no. 11: 2605-2613.

Review
Published: 15 June 2019 in Nutrients
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The role of oxidative stress, an imbalance between reactive oxygen species production (ROS) and antioxidants, has been described in several patho-physiological conditions, including cardiovascular, neurological diseases and cancer, thus impacting on individuals' lifelong health. Diet, environmental pollution, and physical activity can play a significant role in the oxidative balance of an organism. Even if physical training has proved to be able to counteract the negative effects caused by free radicals and to provide many health benefits, it is also known that intensive physical activity induces oxidative stress, inflammation, and free radical-mediated muscle damage. Indeed, variations in type, intensity, and duration of exercise training can activate different patterns of oxidant-antioxidant balance leading to different responses in terms of molecular and cellular damage. The aim of the present review is to discuss (1) the role of oxidative status in athletes in relation to exercise training practice, (2) the implications for muscle damage, (3) the long-term effect for neurodegenerative disease manifestations, (4) the role of antioxidant supplementations in preventing oxidative damages.

ACS Style

Cristina Nocella; Vittoria Cammisotto; Fabio Pigozzi; Paolo Borrione; Chiara Fossati; Alessandra D’Amico; Roberto Cangemi; Mariangela Peruzzi; Giuliana Gobbi; Evaristo Ettorre; Giacomo Frati; Elena Cavarretta; Roberto Carnevale; SMiLe Group. Impairment between Oxidant and Antioxidant Systems: Short- and Long-term Implications for Athletes' Health. Nutrients 2019, 11, 1353 .

AMA Style

Cristina Nocella, Vittoria Cammisotto, Fabio Pigozzi, Paolo Borrione, Chiara Fossati, Alessandra D’Amico, Roberto Cangemi, Mariangela Peruzzi, Giuliana Gobbi, Evaristo Ettorre, Giacomo Frati, Elena Cavarretta, Roberto Carnevale, SMiLe Group. Impairment between Oxidant and Antioxidant Systems: Short- and Long-term Implications for Athletes' Health. Nutrients. 2019; 11 (6):1353.

Chicago/Turabian Style

Cristina Nocella; Vittoria Cammisotto; Fabio Pigozzi; Paolo Borrione; Chiara Fossati; Alessandra D’Amico; Roberto Cangemi; Mariangela Peruzzi; Giuliana Gobbi; Evaristo Ettorre; Giacomo Frati; Elena Cavarretta; Roberto Carnevale; SMiLe Group. 2019. "Impairment between Oxidant and Antioxidant Systems: Short- and Long-term Implications for Athletes' Health." Nutrients 11, no. 6: 1353.

Research article
Published: 06 January 2019 in European Journal of Preventive Cardiology
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Background The aim of this study was to compare the acute effects produced by a single bout of three different exercise modalities on short-term blood pressure variability. Methods The study enrolled 21 sedentary male patients with hypertension and a mean age of 63 ± 7.2 years. Blood pressure variability was evaluated through ambulatory blood pressure monitoring that was performed twice: during an ordinary daily activity and after an exercise session lasting 60 minutes. Patients were divided into three groups according to the different exercise modality performed during the session: aerobic continuous training, interval training or combined training including aerobic and resistance training. Results Twenty-four-hour systolic blood pressure variability increased in the interval training group, was unchanged in the aerobic continuous training group and decreased in the combined training group (intergroup P = 0.03). Daytime systolic blood pressure variability increased in the interval training and aerobic continuous training groups while it decreased in the combined training group (intergroup P = 0.0006). Twenty-four-hour diastolic blood pressure variability decreased in the aerobic continuous training and combined training groups while it increased in the interval training group (intergroup P = 0.002). Conclusion Different training modalities have similar hypotensive action but exert different acute effects on blood pressure variability. Combined training seems to be the most suitable training modality for sedentary men with hypertension.

ACS Style

Giuseppe Caminiti; Annalisa Mancuso; Ana Filipa Raposo; Chiara Fossati; Serena Selli; Maurizio Volterrani. Different exercise modalities exert opposite acute effects on short-term blood pressure variability in male patients with hypertension. European Journal of Preventive Cardiology 2019, 26, 1028 -1031.

AMA Style

Giuseppe Caminiti, Annalisa Mancuso, Ana Filipa Raposo, Chiara Fossati, Serena Selli, Maurizio Volterrani. Different exercise modalities exert opposite acute effects on short-term blood pressure variability in male patients with hypertension. European Journal of Preventive Cardiology. 2019; 26 (10):1028-1031.

Chicago/Turabian Style

Giuseppe Caminiti; Annalisa Mancuso; Ana Filipa Raposo; Chiara Fossati; Serena Selli; Maurizio Volterrani. 2019. "Different exercise modalities exert opposite acute effects on short-term blood pressure variability in male patients with hypertension." European Journal of Preventive Cardiology 26, no. 10: 1028-1031.

Journal article
Published: 01 December 2018 in Current Sports Medicine Reports
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Exercise training is increasingly promoted for physical and mental health and represents a major factor in both primary and secondary prevention of cardiovascular (CV) diseases. The beneficial effects of exercise, in part, can be ascribed to adaptations of neural CV regulation through several mechanisms. In this article, we summarize how exercise training affects neural CV regulation and outline the plasticity of neural network in the continuum from cardiac patients to elite athletes.

ACS Style

Ferdinando Iellamo; Maurizio Volterrani; Alessia Di Gianfrancesco; Chiara Fossati; Maurizio Casasco. The Effect of Exercise Training on Autonomic Cardiovascular Regulation. Current Sports Medicine Reports 2018, 17, 473 -479.

AMA Style

Ferdinando Iellamo, Maurizio Volterrani, Alessia Di Gianfrancesco, Chiara Fossati, Maurizio Casasco. The Effect of Exercise Training on Autonomic Cardiovascular Regulation. Current Sports Medicine Reports. 2018; 17 (12):473-479.

Chicago/Turabian Style

Ferdinando Iellamo; Maurizio Volterrani; Alessia Di Gianfrancesco; Chiara Fossati; Maurizio Casasco. 2018. "The Effect of Exercise Training on Autonomic Cardiovascular Regulation." Current Sports Medicine Reports 17, no. 12: 473-479.

Research article
Published: 18 May 2018 in European Journal of Preventive Cardiology
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Background Several articles have proposed reference values in healthy paediatric subjects, but none of them has evaluated a large population of healthy trained adolescents. Design The study purpose was to establish normal echocardiographic measurements of left heart (aortic root, left atrium and left ventricular dimensions and mass) in relation to age, weight, height, body mass index, body surface area and training hours in this specific population. Methods We retrospectively evaluated 2151 consecutive, healthy, peri-pubertal athletes (100% male, mean age 12.4 ± 1.4 years, range 8–18) referred to a single centre for pre-participation screening. All participants were young soccer athletes who trained for a mean of 7.2 ± 1.1 h per week. Results Left ventricular internal diameters, wall thickness, left ventricular mass, aortic root and left atrium diameters were significantly correlated to age, body surface area, height and weight ( p < 0.01). Age, height, weight and body surface area were found associated with chamber size, while body mass index and training hours were not. Inclusion of both age and body size parameters in the statistical models resulted in improved overall explained variance for diameters and left ventricular mass. Conclusion Equations, mean values and percentile charts for the different age groups may be useful as reference data in efficiently assessing left ventricular parameters in young athletes.

ACS Style

Elena Cavarretta; Francesco Maffessanti; Fabio Sperandii; Emanuele Guerra; Federico Quaranta; Antonia Nigro; Monia Minati; Marco Rebecchi; Chiara Fossati; Leonardo Calò; Fabio Pigozzi. Reference values of left heart echocardiographic dimensions and mass in male peri-pubertal athletes. European Journal of Preventive Cardiology 2018, 25, 1204 -1215.

AMA Style

Elena Cavarretta, Francesco Maffessanti, Fabio Sperandii, Emanuele Guerra, Federico Quaranta, Antonia Nigro, Monia Minati, Marco Rebecchi, Chiara Fossati, Leonardo Calò, Fabio Pigozzi. Reference values of left heart echocardiographic dimensions and mass in male peri-pubertal athletes. European Journal of Preventive Cardiology. 2018; 25 (11):1204-1215.

Chicago/Turabian Style

Elena Cavarretta; Francesco Maffessanti; Fabio Sperandii; Emanuele Guerra; Federico Quaranta; Antonia Nigro; Monia Minati; Marco Rebecchi; Chiara Fossati; Leonardo Calò; Fabio Pigozzi. 2018. "Reference values of left heart echocardiographic dimensions and mass in male peri-pubertal athletes." European Journal of Preventive Cardiology 25, no. 11: 1204-1215.

Journal article
Published: 01 November 2017 in International Journal of Cardiology
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ACS Style

Chiara Fossati; Maurizio Volterrani; Noemi Punzo; Giuseppe Campolongo; Giovanna Cascelli; Giuseppe Caminiti. Dose-dependent effects of ivabradine on heart rate during maximal efforts in a woman with permanent atrial fibrillation. International Journal of Cardiology 2017, 247, 37 .

AMA Style

Chiara Fossati, Maurizio Volterrani, Noemi Punzo, Giuseppe Campolongo, Giovanna Cascelli, Giuseppe Caminiti. Dose-dependent effects of ivabradine on heart rate during maximal efforts in a woman with permanent atrial fibrillation. International Journal of Cardiology. 2017; 247 ():37.

Chicago/Turabian Style

Chiara Fossati; Maurizio Volterrani; Noemi Punzo; Giuseppe Campolongo; Giovanna Cascelli; Giuseppe Caminiti. 2017. "Dose-dependent effects of ivabradine on heart rate during maximal efforts in a woman with permanent atrial fibrillation." International Journal of Cardiology 247, no. : 37.

Original articles
Published: 12 September 2017 in Platelets
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The aim of the present retrospective observational study was to evaluate the time of functional recovery following a specific combined therapeutic approach characterized by an active exercise therapy carried out immediately after Platelet-rich plasma (PRP) injections for the treatment of the muscular lesion of the distal musculotendinous junction of the gastrocnemius medial head.Medical records of 31 subjects treated with three PRP intra-lesional ultrasound guided injections and 30 patients treated with the standard therapeutic approach (control group) were analyzed. Both groups followed the same rehabilitation therapy. Patients in the control group were able to start active exercise with a significant delay when compared to the PRP treated subjects: 17 ± 7.2 days and 9 ± 3.8 days (p = 0.0001), respectively. This delay was mainly due to the persistence of pain in the subjects in the control group. The time necessary to return to walk without pain was significantly shorter in the PRP treated group: 24.27 ± 12.36 days versus 52.4 ± 20.03 days in the control group (p < 0.001) as well as the time needed to fully return to practice the previous sport activity: 53.33 ± 27.74 days versus 119.3 ± 43.87 days in the control group (p < 0.001).The present study showed that ultrasound guided delivery of PRP into the site of muscle injury has to be considered a valid therapeutic approach with the potentiality of significantly reduce time and costs for reaching a complete functional recovery.

ACS Style

Paolo Borrione; Chiara Fossati; Maria Teresa Pereira; Silvana Giannini; Marco Davico; Carlo Minganti; Fabio Pigozzi. The use of platelet-rich plasma (PRP) in the treatment of gastrocnemius strains: a retrospective observational study. Platelets 2017, 29, 596 -601.

AMA Style

Paolo Borrione, Chiara Fossati, Maria Teresa Pereira, Silvana Giannini, Marco Davico, Carlo Minganti, Fabio Pigozzi. The use of platelet-rich plasma (PRP) in the treatment of gastrocnemius strains: a retrospective observational study. Platelets. 2017; 29 (6):596-601.

Chicago/Turabian Style

Paolo Borrione; Chiara Fossati; Maria Teresa Pereira; Silvana Giannini; Marco Davico; Carlo Minganti; Fabio Pigozzi. 2017. "The use of platelet-rich plasma (PRP) in the treatment of gastrocnemius strains: a retrospective observational study." Platelets 29, no. 6: 596-601.