Said Mekary

Dr. Said Mekary


Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 February 2020 in Brain Sciences
Verified
Journal Article
Open access
PDF file
SMSaid Mekary
Said Mekary
MEMeghan Earle
Meghan Earle
RMRicardo Martins
Ricardo Martins
SDSara Drisdelle
Sara Drisdelle
MKMelanie Killen
Melanie Killen
Olivier DupuyOlivier Dupuy
Olivier Dupuy
To improve cognitive function, moving the body is strongly recommended; however, evidence regarding the proper training modality is still lacking. The purpose of this study was therefore to assess the effects of high intensity interval training (HIIT) compared to moderate intensity continuous exercise (MICE), representing the same total training load, on improving cognitive function in healthy adults. It was hypothesized that after 6 weeks (3 days/week) of stationary bike training, HIIT would improve executive functions more than MICE. Twenty-five participants exercised three times a week for 6 weeks after randomization to the HIIT or MICE training groups. Target intensity was 60% of peak power output (PPO) in the MICE group and 100% PPO in the HIIT group. After training, PPO significantly increased in both the HIIT and MICE groups (9% and 15%, p < 0.01). HIIT was mainly associated with a greater improvement in overall reaction time in the executive components of the computerized Stroop task (980.43 ± 135.27 ms vs. 860.04 ± 75.63 ms, p < 0.01) and the trail making test (42.35 ± 14.86 s vs. 30.35 ± 4.13 s, p < 0.01). T exercise protocol was clearly an important factor in improving executive functions in young adults.

29 October 2020 in Brain Sciences
Verified
Journal Article
Open access
PDF file
SMSaid Mekary
Said Mekary
HNHeather F. Neyedli
Heather F. Neyedli
SFSarah Fraser
Sarah Fraser
MOMyles O'Brien
Myles O'Brien
RMRicardo Martins
Ricardo Martins
Olivier DupuyOlivier Dupuy
Olivier Dupuy
Introduction: Regular aerobic exercise is associated with better executive function in older adults. It is unclear if high-intensity-interval-training (HIIT) elicits moderate-intensity continuous training (MICT) or resistance training (RT). We hypothesized that HIIT would augment executive function more than MICT and RT. Methods: Sixty-nine older adults (age: 68 ± 7 years) performed six weeks (three days/week) of HIIT (2 × 20 min bouts alternating between 15 s intervals at 100% of peak power output (PPO) and passive recovery (0% PPO); n = 24), MICT (34 min at 60% PPO; n = 19), or whole-body RT (eight exercise superior improvements in executive function of older adults than moderate-intensity-continuous-training, 2 × 10 repetitions; n = 26). Cardiorespiratory fitness (i.e., V˙O2max) and executive function were assessed before and after each intervention via a progressive maximal cycle ergometer protocol and the Stroop Task, respectively. Results: The V˙O2max findings revealed a significant group by time interaction (p = 0.001) in which all groups improved following training, but HIIT and MICT improved more than RT. From pre- to post-training, no interaction in the naming condition of the Stroop Task was observed (p > 0.10). However, interaction from pre- to post-training by group was observed, and only the HIIT group exhibited a faster reaction time (from 1250 ± 50 to 1100 ± 50 ms; p < 0.001) in switching (cognitive flexibility). Conclusion: Despite similar improvements in cardiorespiratory fitness, HIIT, but not MICT nor RT, enhanced cognitive flexibility in older adults. Exercise programs should consider using HIIT protocols in an effort to combat cognitive decline in older adults.

1 October 2019 in GeroScience
Verified
Journal Article
Closed access
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SMSaid Mekary
Said Mekary
Olivier DupuyOlivier Dupuy
Olivier Dupuy
RMRicardo Martins
Ricardo Martins
KEKailey Evans
Kailey Evans
DKDerek S. Kimmerly
Derek S. Kimmerly
HNHeather F. Neyedli
Heather F. Neyedli

3 June 2021 in GeroScience
Verified
Journal Article
Closed access
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MOMyles W. O’brien
Myles W. O’brien
DKDerek S. Kimmerly
Derek S. Kimmerly
SMSaid Mekary
Said Mekary

31 May 2022 in Brain Sciences
Verified
Journal Article
Open access
PDF file
MLMichel T. Léger
Michel T. Léger
SMSaid Mekary
Said Mekary
Purpose: This one-group pretest–posttest, designed within a subject study, looks to compare the effects of an outdoor nature walk (ONW) to those of a virtual nature walk (VRW) on memory and cognitive function. Implications are discussed for education as well as for the world of virtual reality. Methods: Sixty-four healthy university students were asked to complete an ONW and a VRW, which was created using 3D video of the same nature trail used for the ONW. The VRW condition involved a five-minute walk on a treadmill, while wearing a virtual reality mask (Oculus, San Francisco, USA) that projected a previously recorded three-dimensional capture of the same nature walk they experienced outdoors. Both experimental conditions lasted approximately 5 min and were counterbalanced between participants. A Digit Span Test (Digit) for working memory and a Trail Test (TMT) for executive function were administered to all study participants, immediately before and after each type of walk. Results: For executive function testing (Trail Making Test), our results demonstrate that both the ONW and VRW condition improved the TMT time, when compared to a baseline (ONW 37.06 ± 1.31 s vs. 31.75 ± 1.07 s, p < 0.01 and VRW 36.19 ± 1.18 s vs. 30.69 ± 1.11 s, p < 0.01). There was no significant difference between the ONW and VRW groups. Similarly, for the Digit memory task, both conditions improved compared to the baseline (ONW 54.30 ± 3.01 vs. 68.4 ± 2.66, p < 0.01 and VRW 58.1 ± 3.10 vs. 67.4 ± 2.72, p < 0.01). There was a difference at the baseline between the ONW and VRW conditions (54.3 ± 3.01 vs. 58.1 ± 3.10, p < 0.01), but this baseline difference in memory performance was no longer significant post exercise, between groups at follow-up (68.4 ± 2.66 vs. 67.4 ± 2.72, p < 0.08). Conclusions: Our results suggest that both a virtual reality protocol and a nature walk can have positive outcomes on memory and executive function in younger adults.

17 July 2024 in GeroScience
Verified
Journal Article
Closed access
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MCMolly K. Courish
Molly K. Courish
MOMyles O'Brien
Myles O'Brien
SMSelena Maxwell
Selena Maxwell
SMSaid Mekary
Said Mekary
DKDerek Kimmerly
Derek Kimmerly
OTOlga Theou
Olga Theou