The NW Mediterranean region experiences every year heavy rainfall and flash floods that occasionally produce catastrophic damages. Less frequent are floods that affect large regions. Although a large number of databases devoted exclusively to floods or considering all kind of natural hazards do exist, usually they only record catastrophic flood events. This paper deals with the new flood database that is being developed within the framework of HYMEX project. Results are focused on four regions representative of the NW sector of Mediterranean Europe: Catalonia, Spain; the Balearic Islands, Spain; Calabria, Italy; and Languedoc-Roussillon, Midi-Pyrénées and PACA, France. The common available 30-yr period starts in 1981 and ends in 2010. The paper shows the database structure and criteria, the comparison with other flood databases, some statistics on spatial and temporal distribution, and an identification of the most important events. The paper also provides a table that includes the date and affected region of all the catastrophic events identified in the regions of study, in order to make this information available for all audiences.

Floods and landslides are frequent and destructive geo-hydrological hazards that cause harm to people every year. We analysed data on 1292 landslide and 771 flood fatalities that occurred in Italy in the 50-year period 1965-2014, to determine the dependence of the fatalities on gender and age and the circumstances of death by type of hazard. The multinomial probability mass function of the expected fatalities by gender and age, as reported by national census data, were estimated and compared with the observed landslide and flood fatalities. We identified the age categories over or under represented when the observed fatalities were respectively higher or lower than the modelled expected deaths. We found that in Italy males are more vulnerable to floods and landslides for most of the age categories. Apart from children, males are over-represented up to the age of 89 for floods and up to 79 for landslides, whereas females are under-represented up to the age of 59 for floods and landslides, and over-represented above 70 for floods and between 60 and 79 for landslides. To consider the demographic and socio-cultural changes over time, we performed a temporal analysis splitting the record into two non-overlapping subsets of 25year each. The analysis demonstrated that the over-representation of males compared to the females, both for landslide and flood is statistically significant and does not vary in time, indicating a different propensity towards the risk taking and a different degree of exposure between males and females. Analysis of the data allowed to identify the common circumstances of death. Landslides fatalities occurred frequently indoor, whereas the majority of the flood fatalities occurred outdoor, outlining the different dynamics of the hazards. Floods killed numerous people along roads and drivers or passengers travelling in vehicles. We expect that the results of this work will be helpful to design recommendations for self-protecting actions, and proactive policies that can contribute to reduce the human toll of floods and landslides in Italy, and elsewhere.

Floods are still a significant threat to people, despite of the considerable developments in forecasting, management, defensive, and rescue works. In the near future, climate and societal changes as both urbanization of flood prone areas and individual dangerous behaviors could increase flood fatalities. This paper analyzes flood mortality in eight countries using a 39-year database (1980–2018) named EUFF (EUropean Flood Fatalities), which was built using documentary sources. The narratives of fatalities were investigated and standardized in the database reporting the details of the events. The entire dataset shows a stable trend on flood fatalities, despite the existence of individual increasing (Greece, Italy, and South France) and decreasing (Turkey and Catalonia) trends. The 2466 fatalities were mainly males, aged between 30–49 years and the majority of them happened outdoor. Most often people were dragged by water/mud when travelling by motor vehicles. Some cases of hazardous behaviors, such as fording rivers, were also detected. The primary cause of death was drowning, followed by heart attack. This work contributes to understand the human–flood interaction that caused fatalities. The changes in society’s vulnerability highlighted throughout this study contribute to manage future risks, to improve people protection actions, and to reduce risk behaviors.

Background: Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is caused by mutations in the α4 subunit of the neuronal nicotinic acetylcholine receptor (CHRNA4) gene, mapping on chromosome 20q13.2. A second ADNFLE locus was mapped on chromosome 15q24. Objective: To report a new third ADNFLE locus on chromosome 1 in a large Italian family. Methods: The authors performed a clinical and genetic study in a large, three-generation ADNFLE family from southern Italy, including eight affected individuals and three obligate carriers. Results: The age at onset of seizures was around 9 years of age and all affected individuals manifested nocturnal partial seizures of frontal lobe origin. Interictal awake and sleep EEG recordings showed no definite epileptiform abnormalities in most patients. Ictal video-EEG showed that the attacks were partial seizures with a frontal lobe semiology. Intellectual and neurologic examinations, and brain CT or MRI results were always normal. Carbamazepine was effective in all treated patients. Exclusion mapping of the known loci linked to ADNFLE—ENFL1, and ENFL2, on chromosomes 20q13.2 and 15q24—was performed on the pedigree before starting the genome-wide linkage analysis. The whole genome scan mapping allowed the identification of a new ADNFLE locus spanning the pericentromeric region of chromosome 1. Conclusions: The authors provided evidence for a third locus associated to autosomal dominant nocturnal frontal lobe epilepsy on chromosome 1. Among the known genes mapping within this critical region, the β2 subunit of the nicotinic receptor (CHRNB2) represents the most obvious candidate.

Recent events in Western Attica in Greece (24 deaths in November 2017), in the Balearic Islands (13 deaths in October 2018), and in southern France (15 deaths in October 2018) show that flood-related mortality remains a major concern in Mediterranean countries facing flash floods. Over the past several years, many initiatives have arisen to create databases on flood-related mortality. An international initiative started in 2011 pooling regional and national databases on flood mortality from region and/or countries bordering the Mediterranean Sea. The MEditerranean Flood Fatality Database (MEFF DB) brings together, in 2018, six Mediterranean regions/countries: Catalonia (Spain), Balearic Islands (Spain), Southern France, Calabria (Italy), Greece, and Turkey, and covers the period 1980–2018. MEFF DB is on progress and, every year, new data are included, but for this study, we kept only the preliminary data that were geolocated and validated on 31st of December 2018. This research introduces a new step in the analysis of flood-related mortality and follows the statistical description of the MEFF DB already published. The goals of this paper are to draw the spatial distribution of flood mortality through a geographical information system (GIS) at different spatial scales: country, NUTS 3 (Nomenclature of Territorial Units for Statistics. Level 3) regions, catchment areas, and grid. A fatality rate (F: number of deaths/year/million of inhabitants) is created to help this analysis. Then, we try to relate mortality to basic (human or physical) drivers such as population density, rainfall seasonality, or rainfall frequency across the Mediterranean Basin. The mapping of F shows a negative mortality gradient between the western and the eastern parts of the Mediterranean Sea. The south of France appears to be the most affected region. The maps also highlight the seasonality of flood-related deaths with the same west–east gradient. It confirms that flood mortality follows the climatological seasonal patterns across the Mediterranean Basin. Flood-related fatalities mainly occur during the early fall season in the western part of the Mediterranean area, while the Easter Basin is affected later, in November or during the winter season. Eastern Turkey introduces another pattern, as mortality is more severe in summer. Mortality maps are then compared with factors that potentially contribute to the occurrence of flood fatalities, such as precipitation intensity (rainfall hazard), to explain geographical differences in the fatality rate. The density of a fatal event is correlated to the population density and the rainfall frequency. Conversely, the average number of deaths per event depends on other factors such as prevention or crisis management.