Stimulation of the vagus nerve, a parasympathetic nerve that controls the neuro-digestive, vascular, and immune systems, induces pain relief, particularly in clinical conditions such as headache and rheumatoid arthritis. Transmission through vagal afferents towards the nucleus of the solitary tract (NST), the central relay nucleus of the vagus nerve, has been proposed as the main physiological mechanism that reduces pain intensity after vagal stimulation. Chronic pain symptoms of fibromyalgia patients might benefit from stimulation of the vagus nerve via normalization of altered autonomic and immune systems causing their respective symptoms. However, multi-session non-invasive vagal stimulation effects on fibromyalgia have not been evaluated in randomized clinical trials. We propose a parallel group, sham-controlled, randomized study to modulate the sympathetic–vagal balance and pain intensity in fibromyalgia patients by application of non-invasive transcutaneous vagus nerve stimulation (tVNS) over the vagal auricular and cervical branches. We will recruit 136 fibromyalgia patients with chronic moderate to high pain intensity. The primary outcome measure will be pain intensity, and secondary measures will be fatigue, health-related quality of life, sleep disorders, and depression. Heart rate variability and pro-inflammatory cytokine levels will be obtained as secondary physiological measures. We hypothesize that multiple tVNS sessions (five per week, for 4 weeks) will reduce pain intensity and improve quality of life as a result of normalization of the vagal control of nociception and immune–autonomic functions. Since both vagal branches project to the NST, we do not predict significantly different results between the two stimulation protocols.

The objective of this research was to study victimization and aggression in adolescent and young couple relationships, as well as to identify the directionality of violence perpetration in a sample of 984 people between 15 and 31 years of age, of which 58.2% were women and 41.8% were men. Regarding the educational level of the population under study, 26% were students of junior high school, senior high school, or vocational training and 56.5% were college students. The research design followed the nonprobability purposive sampling method and used the DVQ-R questionnaire. The results suggest that violence is 65.2% bidirectional and 14.30% unidirectional, being bidirectionality more frequent in psychological violence and decreasing when physical violence occurs. The results reveal the need to integrate the different modalities of dating violence (unidirectional and bidirectional) and unperceived violence –that gives rise to technical abuse– into the different prevention programs addressed to adolescents and youth.

Anodal transcranial direct current stimulation (tDCS) induces long-term potentiation-like plasticity, which is associated with long-lasting effects on different cognitive, emotional, and motor perform

Alcohol consumption in young people is a public health problem. Due to the harmful consequences and the large population using alcoholic substances, it would be important to determine the biological, psychological, and social factors associated with alcohol use and abuse. The main object of this study is to explore which components of impulsivity, according to the main theoretical models, have predictive power regarding alcohol consumption in young people. A secondary objective is to determine if emotional intelligence has a mediating role between the components of impulsivity and alcohol consumption, and thus specifically contribute to the knowledge about the mediation processes between those variables that are involved in the initiation and maintenance of alcohol consumption. For this purpose, 384 participants were recruited (83.1% females, n = 319), with mean age of 20.46 years (SD = 1.90; range 18–25). All participants were alcohol consumers at the beginning of the study. Data collection was conducted via online survey; impulsivity was evaluated by several questionnaires (Sensation Seeking Scale Form V, Barratt Impulsivity Scales 11, and Sensitivity to Punishment and Sensitivity to Reward), and emotional intelligence was evaluated by the Trait Meta-Mood Scale. The results reveal that the dimension of disinhibition (a dimension of the sensation search scale) significantly has the highest predictive value on alcohol consumption. Moreover, our data show that the total effect and direct effect of disinhibition on frequency of alcohol consumption were both significant. The mediating role of emotional intelligence in this process was also significant. These findings show which variables should be considered to prevent alcohol consumption in young people.

Violence in adolescent and young couples is a major issue given its high prevalence and the serious consequences that it brings. For this reason, this research has stated two main objectives. In the first place, to ascertain the level of agreement between both members of the couple both with regard to occurrence and frequency of violence. Second, to ascertain the level of agreement on the frequency of use of conflict resolution strategies in problematic situations in 141 heterosexual couples. The age of the sample was between 17 and 30. The tools used were the DVQ-R questionnaire and the Spanish adaptation by Bonache, Ramírez-Santana, and González-Mendez (2016) of the Inventory of Conflict Resolution Styles (CSRI)The results indicate that of the 141 couples in the sample, 112 were identified as violent, thus indicating a high prevalence of violence within their partner relationships. Regarding the levels of agreement and accordance, statistically significant discrepancies are reflected in the perception of violence between men and women, analyzing both roles (aggression and victimization). Finally, also noteworthy is use of the strategy of negative involvement in conflicts, with significant differences in relation to sex; it is the girls who make the most use of this strategy, and the high level of agreement on the frequency of problem-solving is reflected on that strategy.

Background: Alzheimer's dementia is characterized by significant cortical and subcortical atrophy, causing diverse neuropsychological deficits. According to the somatic marker hypothesis, the areas responsible for generating the somatic markers that anticipate the consequences of a decision and thereby optimize the process would be affected in these patients. Objective: The aim of this experiment is to study the decision-making processes in Alzheimer type dementia patients to determine potential deficits in these processes as a result of the disease, aside from the cognitive impairment that is typical of aging. In addition, we wish to determine the defining characteristics of decision-making in these patients, on the basis of the prospect valence-learning parameters. Method: We evaluated 30 patients with Alzheimer's disease and a control group of 30 healthy subjects. A short version of the Iowa Gambling Task was used. Results: The results showed that patients made less advantageous choices than did controls. Group differences were quantitative and qualitative, as significant differences in cognitive mechanisms identified in the prospect valence-learning decisions were observed. These results are consistent with evidence from neuroimaging studies as well as with work carried out with amnesic patients. Conclusion: That problems in our patients' decision-making could be due to the characteristic memory deficits of this disease, which prevents them from establishing new stimulus-reward relationships and eliminating previously learned responses as a result of the parietal and temporal atrophy they present.