We report a case of delirium with anticholinergic symptoms in a 19-year-old female patient with schizophrenia. On the day the symptoms emerged, the patient received olanzapine long-acting injection and a higher dose of paliperidone. We observed symptoms ranging from confusion to delirium as well as some anticholinergic symptoms. The delirium lasted 24 hours and was managed by intravenous fluid substitution and oral benzodiazepines. Olanzapine pamoate, paliperidone and cannabis are central nervous system (CNS) depressants, and their combination can increase the risks of CNS depression. In this case report, we review the symptoms of delirium in a case of antipsychotic overdose and provide general guidelines for managing these symptoms. We also review possible complications in combined use of cannabis, olanzapine and paliperidone.
When designing a single tube practical acoustic thermometer (PAT), certain considerations should be addressed for optimal performance. This paper is concerned with the main issues involved in building a reliable PAT. It has to be emphasised that a PAT measures the ratio of the time delay between the single temperature calibration point (ice point) and any other temperature. Here, we present different models of the speed of sound in tubes, including the effects of real gases and an error analysis of the most accurate model with a Monte Carlo simulation. Additionally, we introduce the problem of acoustic signal overlap and some possible solutions, one of which is acoustic signal cancellation, which aims to eliminate the unwanted parts of an acoustic signal, and another is to optimize the tube length for the parameters of the gas used and specific temperature range.
This article presents a Johnson noise thermometer with a signal acquisition system based on a sound card. The thermometer uses a simple analogue circuit to measure the Johnson noise on a resistor. No external hardware or power supply is necessary, except for a reference multimeter. Data processing is performed in real time on a personal computer using LabView software. The results show that the developed thermometer has an expanded uncertainty (k = 2) of 0.8 ℃ over a temperature range from − 196 ℃ to 300 ℃, with a measurement time of 5 min.
2 September 2015 in Journal of Health Policy & Outcomes Research