Asthma and chronic obstructive pulmonary disease are obstructive respiratory diseases that affect negatively the quality of life for patients and their families worldwide. Despite the significance of these diseases, their management has been considered suboptimal around the world, whereas the improper inhaler use has been underlined as one of the main causes. Toward this direction, this paper presents an integrated mHealth system that provides real-time personalized feedback to patients for assessing the proper medication use and educating them and helping them avoid common mistakes. The identification of proper inhaler use is based on conventional and data-driven feature extraction and classification methods employed for the identification of four events (inhaler actuation, inhalation, exhalation, and background noise). The proposed scheme reaches 98% classification accuracy significantly outperforming recent and relevant state-of-the-art approaches. Finally, intuitive feedback interfaces were implemented in the form of a virtual guidance agent integrated with the mobile application, which can help patients follow their action plan and assess their inhaler technique in a more engaging manner. Extensive simulation studies, carried out using 12 subjects, demonstrated the efficiency of the proposed approaches in both indoor and outdoor environments.

Recent advances in 3-D scanning technology have enabled the deployment of 3-D models in various industrial applications such as digital twins, remote inspection, and reverse engineering. Despite their evolving performance, 3-D scanners still introduce noise and artifacts in the acquired dense models. In this article, we propose a fast and robust denoising method for the dense 3-D scanned industrial models. The proposed approach employs conditional variational autoencoders to effectively filter face normals. Training and inference are performed in a sliding patch setup reducing the size of the required training data and execution times. We conducted extensive evaluation studies using 3-D scanned and CAD models. The results verify plausible denoising outcomes, demonstrating similar or higher reconstruction accuracy, compared to other state-of-the-art approaches. Specifically, for 3-D models with more than 1e4 faces, the presented pipeline is twice as fast as methods with equivalent reconstruction error.

Nowadays, the preservation and maintenance of historical objects is the main priority in the area of the heritage culture. The new generation of 3D scanning devices and the new assets of technological improvements have created a fertile ground for developing tools that could facilitate challenging tasks which traditionally required a huge amount of human effort and specialized knowledge of experts (e.g., a detailed inspection of defects in a historical object due to aging). These tasks demand more human effort, especially in some special cases, such as the inspection of a large-scale or remote object (e.g., tall columns, the roof of historical buildings, etc.), where the preserver expert does not have easy access to it. In this work, we propose a saliency aware compression and simplification framework for efficient remote inspection of Structure From Motion (SFM) reconstructed heritage 3D models. More specifically, we present a Convolutional Neural Network (CNN) based saliency map extraction pipeline that highlights the most important information of a 3D model.These include geometric details such as the fine features of the model or surface defects. An extensive experimental study, using a large number of real SFM reconstructed heritage 3D models, verifies the effectiveness and the robustness of the proposed method providing very promising results and draws future directions.

This paper presents AVATREE, a computational modelling framework that generates Anatomically Valid Airway tree conformations and provides capabilities for simulation of broncho-constriction apparent in obstructive pulmonary conditions. Such conformations are obtained from the personalized 3D geometry generated from computed tomography (CT) data through image segmentation. The patient-specific representation of the bronchial tree structure is extended beyond the visible airway generation depth using a knowledge-based technique built from morphometric studies. Additional functionalities of AVATREE include visualization of spatial probability maps for the airway generations projected on the CT imaging data, and visualization of the airway tree based on local structure properties. Furthermore, the proposed toolbox supports the simulation of broncho-constriction apparent in pulmonary diseases, such as chronic obstructive pulmonary disease (COPD) and asthma. AVATREE is provided as an open-source toolbox in C++ and is supported by a graphical user interface integrating the modelling functionalities. It can be exploited in studies of gas flow, gas mixing, ventilation patterns and particle deposition in the pulmonary system, with the aim to improve clinical decision making.

Asthma is a common, usually long-term respiratory disease with negative impact on global society and economy. Treatment involves using medical devices (inhalers) that distribute medication to the airways and its efficiency depends on the precision of the inhalation technique. There is a clinical need for objective methods to assess the inhalation technique, during clinical consultation. Integrated health monitoring systems, equipped with sensors, enable the recognition of drug actuation, embedded with sound signal detection, analysis and identification from intelligent structures, that could provide powerful tools for reliable content management. Health monitoring systems equipped with sensors, embedded with sound signal detection, enable the recognition of drug actuation and could be used for effective audio content analysis. This paper revisits sound pattern recognition with machine learning techniques for asthma medication adherence assessment and presents the Respiratory and Drug Actuation (RDA) Suite ^a for benchmarking and further research. The RDA Suite includes a set of tools for audio processing, feature extraction and classification procedures and is provided along with a dataset, consisting of respiratory and drug actuation sounds. The classification models in RDA are implemented based on conventional and advanced machine learning and deep networks’ architectures. This study provides a comparative evaluation of the implemented approaches, examines potential improvements and discusses on challenges and future tendencies.