Dr. Takumi Kawaguchi
Kurume University School of Medicine
'%3e%3cpath%20d='M22.1642%2019.0924C21.7317%2018.068%2021.1041%2017.1375%2020.3163%2016.3527C19.5309%2015.5656%2018.6006%2014.9381%2017.5766%2014.5048C17.5674%2014.5002%2017.5582%2014.4979%2017.5491%2014.4933C18.9774%2013.4616%2019.9059%2011.7811%2019.9059%209.88504C19.9059%206.74408%2017.3611%204.19922%2014.2201%204.19922C11.0792%204.19922%208.53429%206.74408%208.53429%209.88504C8.53429%2011.7811%209.46282%2013.4616%2010.8912%2014.4956C10.882%2014.5002%2010.8728%2014.5025%2010.8636%2014.5071C9.83652%2014.9404%208.91487%2015.5617%208.1239%2016.355C7.33685%2017.1404%206.70933%2018.0707%206.276%2019.0947C5.85031%2020.0972%205.62072%2021.172%205.59967%2022.2609C5.59905%2022.2853%205.60335%2022.3097%205.61229%2022.3325C5.62123%2022.3553%205.63465%2022.376%205.65174%2022.3935C5.66883%2022.4111%205.68926%2022.425%205.71182%2022.4345C5.73437%2022.444%205.7586%2022.4489%205.78308%2022.4489H7.15868C7.25956%2022.4489%207.3398%2022.3686%207.3421%2022.2701C7.38795%2020.5001%208.09868%2018.8425%209.35506%2017.5861C10.655%2016.2862%2012.3814%2015.5709%2014.2201%2015.5709C16.0588%2015.5709%2017.7852%2016.2862%2019.0852%2017.5861C20.3415%2018.8425%2021.0523%2020.5001%2021.0981%2022.2701C21.1004%2022.3709%2021.1807%2022.4489%2021.2815%2022.4489H22.6571C22.6816%2022.4489%2022.7058%2022.444%2022.7284%2022.4345C22.751%2022.425%2022.7714%2022.4111%2022.7885%2022.3935C22.8056%2022.376%2022.819%2022.3553%2022.8279%2022.3325C22.8369%2022.3097%2022.8412%2022.2853%2022.8406%2022.2609C22.8176%2021.165%2022.5907%2020.0989%2022.1642%2019.0924ZM14.2201%2013.8284C13.1678%2013.8284%2012.1773%2013.418%2011.4322%2012.6729C10.6871%2011.9278%2010.2767%2010.9374%2010.2767%209.88504C10.2767%208.83271%2010.6871%207.84227%2011.4322%207.09715C12.1773%206.35204%2013.1678%205.94165%2014.2201%205.94165C15.2724%205.94165%2016.2629%206.35204%2017.008%207.09715C17.7531%207.84227%2018.1635%208.83271%2018.1635%209.88504C18.1635%2010.9374%2017.7531%2011.9278%2017.008%2012.6729C16.2629%2013.418%2015.2724%2013.8284%2014.2201%2013.8284Z'%20fill='%238590A2'/%3e%3c/g%3e%3c/svg%3e)
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Academic Career Length
29Years (1998-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 January 2017 in Journal of Hepatology
Journal Article
RHRyuki Hashida
Ryuki Hashida
Takumi KawaguchiMBMasafumi Bekki
Masafumi Bekki
MOMasayuki Omoto
Masayuki Omoto
HMHiroo Matsuse
Hiroo Matsuse
TTTakuji Torimura
Takuji Torimura
+6
1 November 2004 in The American Journal of Pathology
Journal Article
Takumi KawaguchiTYTakafumi Yoshida
Takafumi Yoshida
MHMasaru Harada
Masaru Harada
THTakao Hisamoto
Takao Hisamoto
YNYumiko Nagao
Yumiko Nagao
MSMichio Sata
Michio Sata
+11
30 November 2020 in Liver International
Journal Article
SYSakura Yamamura
Sakura YamamuraMEMohammed Eslam
Mohammed EslamTakumi KawaguchiTTTsubasa Tsutsumi
Tsubasa TsutsumiDNDan Nakano
Dan NakanoTTTakuji Torimura
Takuji Torimura
+4
11 May 2011 in Hepatology
Journal Article
Takumi KawaguchiNINamiki Izumi
Namiki Izumi
MCMichael R. Charlton
Michael R. Charlton
MSMichio Sata
Michio Sata
Branched-chain amino acids (BCAAs) are a group of essential amino acids comprising valine, leucine, and isoleucine. A low ratio of plasma BCAAs to aromatic amino acids is a physiological hallmark of liver cirrhosis, and BCAA supplementation was originally devised with the intention of normalizing amino acid profiles and nutritional status. However, recent studies on BCAAs have revealed that, in addition to their role as protein constituents, they may have a role as pharmacological nutrients for patients with chronic liver disease. Large-scale, multicenter, randomized, double-blinded, controlled trials on BCAA supplementation have been performed in Italy and Japan, and results demonstrate that BCAA supplementation improves not only nutritional status, but also prognosis and quality of life in patients with liver cirrhosis. Moreover, accumulating experimental evidence suggests that the favorable effects of BCAA supplementation on prognosis may be supported by unforeseen pharmacological actions of BCAAs. This review summarizes the possible effects of BCAAs on albumin synthesis and insulin resistance from clinical and basic viewpoints. We also review the newly discovered clinical impact of BCAAs on hepatocellular carcinoma and the prognosis and quality of life of patients with liver cirrhosis. (HEPATOLOGY 2011;)
1 January 2013 in World Journal of Gastroenterology
Journal Article
MIMinoru Itou
Minoru Itou
Takumi KawaguchiETEitaro Taniguchi
Eitaro Taniguchi
MSMichio Sata
Michio Sata
Dipeptidyl peptidase-4: A key player in chronic liver disease
15 June 2021 in Hepatology Research
Journal Article
TTTsubasa Tsutsumi
Tsubasa TsutsumiMEMohammed Eslam
Mohammed Eslam
Takumi KawaguchiSYSakura Yamamura
Sakura YamamuraAKAtsushi Kawaguchi
Atsushi Kawaguchi
TTTakuji Torimura
Takuji Torimura +6
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