Christian Hans Nickel

Dr. Christian Hans Nickel

orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 September 2020 in Annals of Emergency Medicine
Verified
Journal Article
Closed access
TKTobias Kaeppeli
Tobias Kaeppeli
MRMarco Rueegg
Marco Rueegg
TDThomas Dreher-Hummel
Thomas Dreher-Hummel
MBMikkel Brabrand
Mikkel Brabrand
SKSøren Kabell-Nissen
Søren Kabell-Nissen
CNChristian Hans Nickel
Christian Hans Nickel

21 July 2022 in Internal and Emergency Medicine
Verified
Journal Article
Open access
PDF file
CFChristophe Fehlmann
Christophe Fehlmann
CNChristian Hans Nickel
Christian Hans Nickel
ECEmily Cino
Emily Cino
ZAZinnia Al-Najjar
Zinnia Al-Najjar
NLNigèle Langlois
Nigèle Langlois
DEDebra Eagles
Debra Eagles
Background: Frailty is a common condition present in older Emergency Department (ED) patients that is associated with poor health outcomes. The Clinical Frailty Scale (CFS) is a tool that measures frailty on a scale from 1 (very fit) to 9 (terminally ill). The goal of this scoping review was to describe current use of the CFS in emergency medicine and to identify gaps in research. Methods: We performed a systemic literature search to identify original research that used the CFS in emergency medicine. Several databases were searched from January 2005 to July 2021. Two independent reviewers completed screening, full text review and data abstraction, with a focus on study characteristics, CFS assessment (evaluators, timing and purpose), study outcomes and statistical methods. Results: A total of 4818 unique citations were identified; 34 studies were included in the final analysis. Among them, 76% were published after 2018, mainly in Europe or North America (79%). Only two assessed CFS in the pre-hospital setting. The nine-point scale was used in 74% of the studies, and patient consent was required in 69% of them. The main reason to use CFS was as a main exposure (44%), a potential predictor (15%) or an outcome (15%). The most frequently studied outcomes were mortality and hospital admission. Conclusion: The use of CFS in emergency medicine research is drastically increasing. However, the reporting is not optimal and should be more standardized. Studies evaluating the impact of frailty assessment in the ED are needed. Registration: https://doi.org/10.17605/OSF.IO/W2F8N

28 August 2015 in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Verified
Journal Article
Open access
PDF file
KJKarin Jordi
Karin Jordi
FGFlorian Grossmann
Florian Grossmann
GGGary M. Gaddis
Gary M. Gaddis
ECEva Cignacco
Eva Cignacco
KDKris Denhaerynck
Kris Denhaerynck
CNChristian Hans Nickel
Christian Hans Nickel
The Emergency Severity Index (ESI) is an English language emergency department patient triage tool. After translation, it has been adapted for use to triage patients in growing numbers of emergency departments in non-English-speaking countries. Few reports of the proficiency of triage nurses to score an ESI exist. We sought to determine accuracy, inter-rater reliability, and subjective confidence of triage nurses at four hospitals to determine an ESI from standardized ESI scenarios. Triage nurses assigned an ESI score to each of 30 standard ESI (ESI Implementation Handbook Version 4) translated teaching case scenarios. Accuracy and Inter-rater reliability (Krippendorff’s alpha) of the ESI scoring was measured. Nurses’ subjective confidence applying the ESI algorithm was obtained by a Likert scale. Sixty-nine nurses from four EDs participated in the study. They scored 59.6 % of the case scenarios correctly. Inter-rater reliability was 0.78 (Krippendorff’s alpha). Most (54/69, 78 %) felt confident in their ability to apply the ESI. Low accuracy of ESI score assignment was observed when nurses scored an ESI for 30 standard written case scenarios, translated into nurses’ native language, despite a good inter-rater reliability and high nurse confidence in their ability to apply the ESI. Although feasible, using standard written case scenarios to determine ESI triage scoring effectiveness may not be the optimum means to rate nurses’ triage skills.

25 August 2014 in PLOS ONE
Verified
Journal Article
Open access
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FGFlorian F Grossmann
Florian F Grossmann
TZThomas Zumbrunn
Thomas Zumbrunn
SCSandro Ciprian
Sandro Ciprian
FSFrank-Peter Stephan
Frank-Peter Stephan
NWNatascha Woy
Natascha Woy
CNChristian Hans Nickel
Christian Hans Nickel
The aim of this study was to investigate the long-term effect of a teaching intervention designed to reduce undertriage rates in older ED patients. Further, to test the hypothesis that non-adherence to the Emergency Severity Index (ESI) triage algorithm is associated with undertriage. Additionally, to detect patient related risk factors for undertriage. Pre-post-test design. The study sample consisted of all patients aged 65 years or older presenting to the ED of an urban tertiary and primary care center in the study periods. A teaching intervention designed to increase adherence to the triage algorithm. To assess, if the intervention resulted in an increase of factual knowledge, nurses took a test before and immediately after the teaching intervention. Undertriage rates were assessed one year after the intervention and compared to the pre-test period. In the pre-test group 519 patients were included, and 394 in the post-test-group. Factual knowledge among triage nurses was high already before the teaching intervention. Prevalence of undertriaged patients before (22.5%) and one year after the intervention (24.2%) was not significantly different (χ2 = 0.248, df = 1, p = 0.619). Sex, age, mode of arrival, and type of complaint were not identified as independent risk factors for undertriage. However, undertriage rates increased with advancing age. Adherence to the ESI algorithm is associated with correct triage decisions. Undertriage of older ED patients remained unchanged over time. Reasons for undertriage seem to be more complex than anticipated. Therefore, additional contributing factors should be addressed.

13 March 2014 in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Verified
Journal Article
Open access
PDF file
FGFlorian F Grossmann
Florian F Grossmann
Wolfgang HasemannWolfgang Hasemann
Wolfgang Hasemann
AGAndreas Graber
Andreas Graber
RBRoland Bingisser
Roland Bingisser
RKReto W Kressig
Reto W Kressig
CNChristian Hans Nickel
Christian Hans Nickel
Delirium in emergency department (ED) patients occurs frequently and often remains unrecognized. Most instruments for delirium detection are complex and therefore unfeasible for the ED. The aims of this pilot study were first, to confirm our hypothesis that there is an unmet need for formal delirium assessment by comparing informal delirium ratings of ED staff with formal delirium assessments performed by trained research assistants. Second, to test the feasibility of an algorithm for delirium screening, detection and management, which includes the newly developed modified Confusion Assessment Method for the Emergency Department (mCAM-ED) at the ED bedside. Third, to test interrater reliability of the mCAM-ED.

1 August 2021 in European Journal of Radiology
Verified
Journal Article
Open access
LSLena Schmuelling
Lena Schmuelling
FFFabian C. Franzeck
Fabian C. Franzeck
CNChristian Hans Nickel
Christian Hans Nickel
GMGregory Mansella
Gregory Mansella
RBRoland Bingisser
Roland Bingisser
GSGregor Sommer
Gregor Sommer
Rapid communication of CT exams positive for pulmonary embolism (PE) is crucial for timely initiation of anticoagulation and patient outcome. It is unknown if deep learning automated detection of PE on CT Pulmonary Angiograms (CTPA) in combination with worklist prioritization and an electronic notification system (ENS) can improve communication times and patient turnaround in the Emergency Department (ED). In 01/2019, an ENS allowing direct communication between radiology and ED was installed. Starting in 10/2019, CTPAs were processed by a deep learning (DL)-powered algorithm for detection of PE. CTPAs acquired between 04/2018 and 06/2020 (n = 1808) were analysed. To assess the impact of the ENS and the DL-algorithm, radiology report reading times (RRT), radiology report communication time (RCT), time to anticoagulation (TTA), and patient turnaround times (TAT) in the ED were compared for three consecutive time periods. Performance measures of the algorithm were calculated on a per exam level (sensitivity, specificity, PPV, NPV, F1-score), with written reports and exam review as ground truth. Sensitivity of the algorithm was 79.6 % (95 %CI:70.8-87.2%), specificity 95.0 % (95 %CI:92.0-97.1%), PPV 82.2 % (95 %CI:73.9-88.3), and NPV 94.1 % (95 %CI:91.4-96 %). There was no statistically significant reduction of any of the observed times (RRT, RCT, TTA, TAT). DL-assisted detection of PE in CTPAs and ENS-assisted communication of results to referring physicians technically work. However, the mere clinical introduction of these tools, even if they exhibit a good performance, is not sufficient to achieve significant effects on clinical performance measures.