Alicia Armentia

Prof. Alicia Armentia


Research Focus & Metrics

Academic Career Length

39Years (1988-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2009 in Allergologia et Immunopathologia
Verified
Journal Article
Closed access
Alicia ArmentiaAlicia Armentia
Alicia Armentia
ADA. Díaz-Perales
A. Díaz-Perales
JCJ. Castrodeza
J. Castrodeza
ADA. Dueñas-Laita
A. Dueñas-Laita
APA. Palacin
A. Palacin
SFS. Fernández
S. Fernández
Diagnosis in patients sensitised to multiple pollens is difficult due to the relationship between pollen and food allergens. Misdiagnosis is often a cause for unsuccessful specific immunotherapy. Wheat is a potent allergen source and is one of the causes of baker's asthma, food and pollen allergy. Recently, we have performed a study on pollen sensitisation in our area, where cereal crops are very important. The clinical data from 19718 patients reviewed showed that grass pollen was the main source of clinical symptoms (6369 patients, 32.30% of asthmatics). However, wheat and cereal crop pollen showed very low prevalence. On the other hand, patients with wheat flour allergy after ingestion and/or with baker's asthma were not sensitised to wheat pollen, despite it containing some common allergens. In the same way, all our asthmatic bakers (135 patients) tolerated the ingestion of bread. Here we try to explain the reason for these surprising observations.

1 June 1996 in Glycobiology
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Journal Article
Open access
PDF file
GGGloria Garcia-Casado
Gloria Garcia-Casado
RSRosa Sanchez-Monge
Rosa Sanchez-Monge
MCMaarten J. Chrispeels
Maarten J. Chrispeels
Alicia ArmentiaAlicia Armentia
Alicia Armentia
GSGabriel Salcedo
Gabriel Salcedo
Luis GomezLuis Gomez
Luis Gomez
Many plant proteins, particularly those found in foods and pollen, are known to act as sensitizing agents in humans upon repeated exposure. Among the cereal flour proteins involved in asthmatic reactions, those members of the α-amylase inhibitor family which are glycosylated, polypeptides BMAI-1, BTAI-CMb*, and WTAI-CM16* are particularly reactive both in vivo and in vitro. We show here that these major glycoprotein allergens carry a single asparagine-linked complex glycan that contains both β1←2 xylose and α1←3 fucose. Evidence is presented that the xylosyl residue and, to a lesser extent, the fucosyl residue are key IgE-binding epitopes and largely responsible for the allergenicity of these and unrelated proteins from plants and insects. Our results suggest that the involvement of xylose- and fucose-containing complex glycans in allergenic responses may have been underestimated previously; these glycans provide a structural basis to help explain the cross-reactivities often observed between pollen, vegetable food, and insect allergens.

1 November 2007 in Journal of Allergy and Clinical Immunology
Verified
Journal Article
Closed access
APArantxa Palacin
Arantxa Palacin
SQSantiago Quirce
Santiago Quirce
Alicia ArmentiaAlicia Armentia
Alicia Armentia
MFMar Fernández-Nieto
Mar Fernández-Nieto
LPLuis F. Pacios
Luis F. Pacios
GSGabriel Salcedo
Gabriel Salcedo

12 February 1990 in FEBS Letters
Verified
Journal Article
Closed access
Luis GomezLuis Gomez
Luis Gomez
EMElena Martin
Elena Martin
DHDolores Hernández
Dolores Hernández
RSRosa Sánchez-Monge
Rosa Sánchez-Monge
DBDomingo Barber
Domingo Barber
FPFilar Palomino
Filar Palomino

1 May 1993 in Clinical & Experimental Allergy
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Journal Article
Closed access
PDF file
Alicia ArmentiaAlicia Armentia
Alicia Armentia
RSR. Sanchez‐Monge
R. Sanchez‐Monge
Luis GomezLuis Gomez
Luis Gomez
DBDomingo Barber
Domingo Barber
GSG. Salcedo
G. Salcedo

1 October 1997 in Clinical & Experimental Allergy
Verified
Journal Article
Closed access
PDF file
RSR. Sánchez‐Monge
R. Sánchez‐Monge
GGG. García‐Casado
G. García‐Casado
CLC. López‐Otín†
C. López‐Otín†
Alicia ArmentiaAlicia Armentia
Alicia Armentia
GSG. Salcedo
G. Salcedo