Introduction: This systematic review synthesizes empirical research on the integration of scientific evidence into public policy formulation across diverse governance contexts. While global support for evidence-informed policymaking is increasing, persistent institutional barriers, political resistance, and limited science-policy interaction continue to constrain the effective use of research in decision-making.Methods: Guided by the PRISMA 2020 framework, the review identified 119 peer-reviewed articles from Scopus and Web of Science databases. Eligible studies included empirical analyses on the mobilization, translation, and institutionalization of scientific knowledge in policy processes. A thematic synthesis was conducted, classifying studies into six categories: science-policy participation, institutional capacity, political dynamics, trust and legitimacy, political support, and international collaboration.Results: Major barriers included fragmented advisory systems, limited data infrastructures, and weak communication between researchers and policymakers. Key enabling factors comprised dedicated scientific advisory bodies, knowledge brokerage mechanisms, international cooperation, and co-production of knowledge. Most studies focused on the health policy sector, with a geographic concentration in high-income countries such as the United Kingdom, the United States, and Canada.Discussion: Findings highlight the urgent need to institutionalize scientific evidence in policy formulation through formal governance frameworks, sustained stakeholder engagement, and robust science-policy interfaces. Advancing transparent, inclusive, and evidence-based governance will require cross-sector collaboration, epistemic trust, and political leadership committed to bridging the gap between research and public policy.

Background/Objectives: Growing evidence suggests that oral microbiota dysbiosis may contribute to the development of systemic conditions, including neurodegenerative diseases. This dysregulation promotes immunoinflammatory responses that are increasingly associated with dementia. This systematic review aimed to evaluate the association between oral microbiota dysbiosis and the risk of dementia in older adults. Methods: Eligible studies evaluated oral microbial composition using validated methods such as genetic sequencing, bacterial culture, or metagenomic analysis. Following PRISMA guidelines and a PICO framework, the review included cohort, case–control, and cross-sectional studies. Searches were conducted across PubMed, Scopus, Web of Science, Embase, and Cochrane Library. Two independent reviewers screened and selected studies, resolving disagreements through a third evaluator. Results: This systematic review revealed that Tannerella forsythia, Fusobacterium nucleatum, Porphyromonas, Prevotella, Leptotrichia, Fusobacteriota, Peptostreptococcaceae, and Candida spp. were consistently associated with Alzheimer’s disease and mild cognitive impairment, indicating their potential role in neurodegeneration. In contrast, Streptococcus gordonii, Gemella haemolysans, Rothia, Neisseria, and Haemophilus were reduced in cognitively impaired individuals, suggesting a link with healthy cognition. Studies also showed decreased microbial diversity in Alzheimer’s disease and the possible modifying effect of the APOE4 allele. Oral health interventions improved microbial composition and slowed cognitive decline, supporting the diagnostic and therapeutic potential of oral microbiota modulation. Conclusions: The findings suggest that oral microbiota dysbiosis may not only result from cognitive decline but also contribute to its pathogenesis. Future studies with larger and more diverse cohorts are recommended to validate these associations.

The concept of Teledentistry started after Telemedicine at the beginning of the 20 th Century. Facebook Messenger, WhatsApp, Google Hangouts, ICQ, iMessage, and recently Telegram Messenger, are some of the most popular instant messaging communication softwares that can be applied in Teledentistry. Motivated by the benefits that Teledentistry can provide to the dental gild, we aim to describe the advantages and characteristics of Telegram Messenger. This particular tool may be the most suitable software given its advantages and features described herein. Finally, this software platform available for Android, iOS, and Desktop. The system allows a significant number of users in channel and groups providing globalization of information, research data, and media files that add to the body of knowledge and good practices resulting in better quality of life for oral and maxillofacial patients. Telemedicine technology has its roots at the beginning of the 20 th Century for emergencies cases, and was later used in the international space stations. 1 Posteriorly, those concepts evolved and entered the dentistry field. Dental medicine, in combination with telecommunication technologies and the internet, has yielded an exciting field that has endless potential, and is commonly known as Teledentistry. 2 This concept has a few branches such as Telestomatology, Teleradiology, Telepathology, Teleoral surgery, and Teleorthodontics. 3 The use of technology through smartphones, personal computers (PC), and other electronic media used in our daily life has become in a regular practice. Technology today is seeing a paradigm shift towards better inter-professional communication, which can help doctors, patients, and the population as a whole. 3,4 Remarkable advances have been made in the use of computers, telecommunication technologies, digital diagnostic imaging services, and specialized hardware and software for patient screening and follow-up; capabilities that were considered out of reach 20 years ago are now a reality in dental care. 5 Since the introduction of social network sites (SNSs) such as MySpace, Facebook, Cyworld, and Bebo, millions of users have adopted these technologies, many of whom have implemented these sites into their daily practices. 4 However, eventually those SNSs were blended with instant messaging chats (IMCh) that acknowledge a rapid communication between users with an interchange of files and media (video, pictures, and sound files) suitable for all users that employ them. 6 Facebook Messenger, WhatsApp, Hangouts, ICQ, iMessage, and recently Telegram Messenger, are a few of the most popular IMCh that can be utilized

Artificial intelligence (AI)-powered adaptive learning systems are revolutionizing higher education by delivering real-time, personalized learning experiences that align with individual student progress. This scoping review maps current evidence on the implementation of such systems in e-learning platforms and evaluates their educational impacts. Fourteen empirical studies published between 2013 and 2025 were systematically analyzed following Arksey & O’Malley and Joanna Briggs Institute methodologies. Findings reveal consistent improvements in academic performance, engagement, retention, and satisfaction across diverse disciplines including law, engineering, dentistry, and language education. Key features enhancing these outcomes include adaptive feedback, curriculum-aligned personalization, and real-time analytics. Nonetheless, barriers such as faculty resistance, ethical concerns like data privacy and algorithmic bias, and regional disparities in adoption—especially in Latin America and Sub-Saharan Africa—persist. The review underscores the transformative potential of AI-based adaptive learning systems while highlighting the need for inclusive design, long-term evaluation, and equitable implementation strategies in higher education.