Geir Bjørklund

Dr. Geir Bjørklund

Council for Nutritional and Environmental Medicine, Mo i Rana, Nordland, Norway
orcid

Research Focus & Metrics

Academic Career Length

38Years (1989-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2018 in International Journal of Nanomedicine
Verified
Journal Article
Open access
PDF file
BHBožena Hosnedlová
Božena Hosnedlová
MKMarta Kepinska
Marta Kepinska
SSSylvie Skalickova
Sylvie Skalickova
Carlos FernandezCarlos Fernandez
Carlos Fernandez
BRBranislav Ruttkay-Nedecky
Branislav Ruttkay-Nedecky
Rene KizekRene Kizek
Rene Kizek
Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this element and allow its controlled release in the organism. Nanoscale selenium has attracted a great interest as a food additive especially in individuals with selenium deficiency, but also as a therapeutic agent without significant side effects in medicine. This review is focused on the incorporation of nanotechnological applications, in particular exploring the possibilities of a more effective way of administration, especially in selenium-deficient organisms. In addition, this review summarizes the survey of knowledge on selenium nanoparticles, their biological effects in the organism, advantages, absorption mechanisms, and nanotechnological applications for peroral administration.

23 February 2023 in Antibiotics
Verified
Journal Article
Open access
PDF file
YAYernar Amangelsin
Yernar Amangelsin
YSYuliya Semenova
Yuliya Semenova
MDMaryam Dadar
Maryam Dadar
MAMohamad Aljofan
Mohamad Aljofan
Geir BjørklundGeir Bjørklund
Geir Bjørklund
Antibacterial drugs are among the most commonly used medications in the world. Tetracycline is a widely used antibiotic for human and animal therapy due to its broad-spectrum activity, high effectiveness, and reasonable cost. The indications for treatment with tetracycline include pneumonia, bone and joint infections, infectious disorders of the skin, sexually transmitted and gastrointestinal infections. However, tetracycline has become a serious threat to the environment because of its overuse by humans and veterinarians and weak ability to degrade. Tetracycline is capable of accumulating along the food chain, causing toxicity to the microbial community, encouraging the development and spread of antibiotic resistance, creating threats to drinking and irrigation water, and disrupting microbial flora in the human intestine. It is essential to address the negative impact of tetracycline on the environment, as it causes ecological imbalance. Ineffective wastewater systems are among the main reasons for the increased antibiotic concentrations in aquatic sources. It is possible to degrade tetracycline by breaking it down into small molecules with less harmful or nonhazardous effects. A range of methods for physical, chemical, and biological degradation exists. The review will discuss the negative effects of tetracycline consumption on the aquatic environment and describe available removal methods.

1 November 2017 in Environmental Research
Verified
Journal Article
Closed access
Geir BjørklundGeir Bjørklund
Geir Bjørklund
Maryam DadarMaryam Dadar
Maryam Dadar
JMJoachim Mutter
Joachim Mutter
JAJan Aaseth
Jan Aaseth

7 May 2020 in Coordination Chemistry Reviews
Verified
Journal Article
Closed access
OAOlga P. Ajsuvakova
Olga P. Ajsuvakova
ATAlexey A. Tinkov
Alexey A. Tinkov
MAMichael Aschner
Michael Aschner
JRJoão B. T. Rocha
João B. T. Rocha
BMBernhard Michalke
Bernhard Michalke
Geir BjørklundGeir Bjørklund
Geir Bjørklund

5 February 2020 in Molecular Neurobiology
Verified
Journal Article
Closed access
PDF file
Geir BjørklundGeir Bjørklund
Geir Bjørklund
NMNagwa A. Meguid
Nagwa A. Meguid
MEMona A. El-Bana
Mona A. El-Bana
ATAlexey A. Tinkov
Alexey A. Tinkov
Khaled SaadKhaled Saad
Khaled Saad
Salvatore ChirumboloSalvatore Chirumbolo
Salvatore Chirumbolo

1 September 2017 in Critical Reviews in Food Science and Nutrition
Verified
Journal Article
Closed access
Joanna Kaluzna-CzaplinskaJoanna Kaluzna-Czaplinska
Joanna Kaluzna-Czaplinska
PGPaulina Gątarek
Paulina Gątarek
Salvatore ChirumboloSalvatore Chirumbolo
Salvatore Chirumbolo
MCMax Stanley Chartrand
Max Stanley Chartrand
Geir BjørklundGeir Bjørklund
Geir Bjørklund
Tryptophan (Trp) is an amino acid and an essential component of the human diet. It plays a crucial role in many metabolic functions. Clinicians can use Trp levels in the course of diagnosing various metabolic disorders and the symptoms associated with those diseases. Furthermore, supplementation with this amino acid is considered in the treatment of depression and sleep disorders, mainly due to the Trp relationship with the synthesis of serotonin (5-HT) and melatonin. It is also used in helping to resolve cognitive disorders, anxiety, or neurodegenerative diseases. Reduced secretion of serotonin is associated with autism spectrum disorder, obesity, anorexia and bulimia nervosa, and other diseases presenting peripherals symptoms. The literature strongly suggests that Trp has a significant role in the correct functionality of the brain-gut axis and immunology. This information leads to the consideration of Trp as an essential dietary component due to its role in the serotonin pathway. A reduced availability of Trp in diet and nutraceutical supplementation should be considered with greater concern than one might expect. This paper constitutes a review of the more salient aspects gleaned from the current knowledge base about the role of Trp in diseases, associated nutritional disorders, and food science, in general.