Izabela Kis

Dr. Izabela Kis

orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 January 2016 in Journal of Cardiothoracic Surgery
Verified
Journal Article
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ZPZrinka Požgain
Zrinka Požgain
GDGrgur Dulić
Grgur Dulić
JKJozo Kristek
Jozo Kristek
JRJasmina Rajc
Jasmina Rajc
SBSiniša Bogović
Siniša Bogović
Izabela KisIzabela Kis
Izabela Kis
Pleomorphic adenomas, also known as benign mixed tumors, are the most common tumors of glandular origin in the head and neck and although they are generally benign they can undergo malignant transformation. Primary pleomorphic adenomas of the lung are extremely rare tumors with less than 40 cases reported in the literature by now. This is the first case in the literature describing overlapping with a traumatic event and also one of the rare cases describing primary adenoma of the lung reaching this impressive size. We report a rare case of a giant primary pleomorphic adenoma of the lung presenting as a post-traumatic pulmonary hematoma. A 38-year-old Caucasian male patient came to the Urgent Trauma Center after being hit in the chest by a bull and, after a number of tests, was diagnosed with primary pleomorphic adenoma of the lung. Operative treatment was performed and the surgical excision was successfully done. Our conclusion is that the surgical excision is the main treatment for pleomorphic adenoma of the lungs and we recommend lifelong follow-up and regular check-ups. Furthermore, we consider our case an interesting one due to its concurrence with the chest trauma and the dilemma about the optimal approach considering the entity could have been a large interlobular hematoma.

18 September 2025 in Medicina
Verified
Journal Article
Open access
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JKJosip Kocur
Josip Kocur
SČSlavko Čičak
Slavko Čičak
DDDamjan Dimnjaković
Damjan Dimnjaković
Izabela KisIzabela Kis
Izabela Kis
GKGordana Kristek
Gordana Kristek
DDDalibor Divković
Dalibor Divković
Background and Objectives: Tibial tuberosity avulsion fractures are rare injuries in pediatric athletes, with limited data on the potential role of an elevated body mass index (BMI) as a risk factor. Previous studies have primarily focused on age, sex, and sport type, but the association between BMI and these injuries remains underexplored. Tibial tuberosity avulsion fractures are rare injuries predominantly affecting adolescent boys during sports activities involving strong quadriceps contractions. This pilot study aimed to analyze the epidemiological and anthropometric characteristics of patients with these fractures, including the distribution of injury mechanisms and the fracture types, to test whether the prevalence of overweight/obesity among cases exceeded national population benchmarks, and to describe the associated clinical outcomes. Materials and Methods: A retrospective analysis was conducted on medical records and radiographs of patients under the age of 18 treated between 2017 and 2024. The data collected included demographic and anthropometric characteristics, injury mechanisms, fracture classification, treatment methods, complications, and outcomes. The patients were categorized as normal weight (<85th percentile) or overweight/obese (≥85th percentile). The primary outcome was whether the prevalence of overweight/obesity among the cases exceeded national pediatric benchmarks. Formal sample size and power analyses were performed to guide future research. Results: Twenty-one patients met the inclusion criteria, with a mean age of 13.7 years; 95.2% were male. Soccer was the most common injury mechanism (52.4%), followed by athletics and running. The predominant fracture type was Ogden IVb (38.1%). Overweight/obesity was present in 52.4% of the patients, significantly higher than the national benchmarks. An open reduction and internal fixation was performed in 90.5% of the cases, with a mean follow-up of 14.6 months (range: 6–36). Complications occurred in 14.3% overall, all within the overweight/obese group (27.3%). Conclusions: This pilot retrospective study suggests a potential link between an elevated BMI and tibial tuberosity avulsion fractures, with overweight/obesity being significantly more prevalent in affected patients than in the general pediatric population. These exploratory findings warrant confirmation in larger, adequately powered studies, and emphasize the importance of weight management and tailored sports activities as potential preventive strategies. An early diagnosis, timely surgical intervention, and adequate rehabilitation are critical for achieving optimal functional recovery.

15 March 2023 in Medicina
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Journal Article
Open access
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VFVlasta Oršić Frič
Vlasta Oršić Frič
VBVladimir Borzan
Vladimir Borzan
ABAndrej Borzan
Andrej Borzan
Izabela KisIzabela Kis
Izabela Kis
BDBranko Dmitrović
Branko Dmitrović
IRIvana Roksandić-Križan
Ivana Roksandić-Križan
The main symptoms of coronavirus disease (COVID-19) are fever, cough, tiredness, and loss of smell and taste. Gastrointestinal symptoms are less common. A 38-year-old female patient, previously healthy, presented with a history of hematochezia up to 8 times per day, followed by abdominal cramps, urgency, and chills for two days. She did not have any respiratory symptoms and was previously vaccinated for COVID-19. She was afebrile, with normal vital signs. Blood samples showed normal complete blood count and increased C-reactive protein (CRP), fibrinogen, and D-dimer levels (66 mg/L, 4.1 g/L, and 2302 μ/L FEU, respectively). Stool samples for stool culture, C. difficile, and viral examination came back negative. On day 3, she reported a mild cough, fever and loss of smell and taste. Nasopharyngeal swab for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) PCR test came back positive. On day 6, the patient still had hematochezia accompanied by abdominal cramps, but fever and respiratory symptoms withdrew. CRP, fibrinogen, and D-dimers were still elevated, as well as liver enzyme levels. Sigmoidoscopy was performed with biopsies taken from sigmoid and rectum for histology and PCR SARS-CoV-2 testing. CT angiography showed no signs of thrombosis in mesenteric veins or arteries. PCR test for SARS-CoV-2 virus from rectal biopsy sample was positive. Patient was treated with methylprednisolone iv for two days and peroral prednisone afterwards, with mesalamine, metronidazole and enoxaparin. Sigmoidoscopy was repeated after two weeks showing only mild hyperemia. At that time, the patient had normal stool, normal CRP, liver enzyme, fibrinogen, and D-dimer levels, and normocytic anemia (hemoglobin level of 103 g/L). We wanted to show that severe gastrointestinal symptoms, such as hemorrhagic colitis, can be the main presentation of COVID-19, even in young patients with no prior comorbidities. In such a case, PCR test in biopsy samples can be performed to prove SARS-CoV-2 infection of bowel mucosa.

14 October 2026 in Pediatric Reports
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Journal Article
Open access
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Izabela KisIzabela Kis
Izabela Kis
Ivana JukićIvana Jukić
Ivana Jukić
BKBorna Kovacic
Borna Kovacic
IBIvancica Bekavac
Ivancica Bekavac
TGTea Grujic-Tomas
Tea Grujic-Tomas
Zenon PogorelićZenon Pogorelić
Zenon Pogorelić
Intestinal mature B-cell non-Hodgkin lymphoma (B-NHL) is the most common pediatric gastrointestinal lymphoma, but presentation as acute mechanical bowel obstruction remains rare and still challenging. Evidence guiding emergency surgical management in children is limited to small retrospective series and case reports. This case series describes three children with intestinal B-NHL presenting with acute mechanical bowel obstruction, or intussusception. All three patients presented to the emergency department with signs of bowel obstruction and an acute abdomen, and in one patient initial diagnosis suggested appendicitis. Imaging revealed either intussusception with a lead mass or large obstructing abdominal tumors. Surgery within 8–48 h consisted of segmental bowel resection with primary anastomosis in all cases. The final diagnoses were Burkitt lymphoma in two patients and diffuse large B-cell lymphoma (DLBCL) in one. The wider literature confirms that lymphoma-related intussusception and obstructing ileal masses occur predominantly in older children, are frequently misdiagnosed preoperatively, and often require emergency surgery both for diagnosis and for treatment of obstruction. Available literature has examined outcomes after emergency surgery for intestinal lymphoma, but the present case series cannot determine its independent effect on long-term oncologic prognosis. Pediatric intestinal B-NHL can present as acute mechanical bowel obstruction or intussusception suggesting common surgical conditions. Surgeons play a crucial role in early recognition, appropriate extent of resection, and timely transition to oncologic care. Further multicenter studies are needed to optimize surgical decision-making and quantify outcomes in this rare but life-threatening presentation.