A crosstalk established between tumor microenvironment and tumor cells leads to contribution or inhibition of tumor progression. Mesenchymal stem cells (MSCs) are critical cells that fundamentally participate in modulation of the tumor microenvironment, and have been reported to be able to regulate and determine the final destination of tumor cell. Conflicting functions have been attributed to the activity of MSCs in the tumor microenvironment; they can confer a tumorigenic or anti-tumor potential to the tumor cells. Nonetheless, MSCs have been associated with a potential to modulate the tumor microenvironment in favouring the suppression of cancer cells, and promising results have been reported from the preclinical as well as clinical studies. Among the favourable behaviours of MSCs, are releasing mediators (like exosomes) and their natural migrative potential to tumor sites, allowing efficient drug delivering and, thereby, efficient targeting of migrating tumor cells. Additionally, angiogenesis of tumor tissue has been characterized as a key feature of tumors for growth and metastasis. Upon introduction of first anti-angiogenic therapy by a monoclonal antibody, attentions have been drawn toward manipulation of angiogenesis as an attractive strategy for cancer therapy. After that, a wide effort has been put on improving the approaches for cancer therapy through interfering with tumor angiogenesis. In this article, we attempted to have an overview on recent findings with respect to promising potential of MSCs in cancer therapy and had emphasis on the implementing MSCs to improve them against the suppression of angiogenesis in tumor tissue, hence, impeding the tumor progression.

Every industry now takes clean technology very seriously. Particularly in textile dying facilities, a lot of water, energy, dyeing colours, and chemicals are used. Significant issues with air and water pollution may result from this. The wastewater is quite colourful and smells poisonous. It also has high chemical oxygen demand (COD) and biochemical oxygen demand (BOD) levels. Reactive dyes found in wastewater include orange OGR, red DB-8, black DN, and turquoise DG. It has been demonstrated that the type of dye, the dosage of coagulant, and the pH of the sample all affect how effectively dye is removed. Also, the effectiveness of COD and colour elimination in single-stage and multi-stage ozonation-biological process methods were studied. The functional groups of azo dye are changed by ozonation to produce more readily removable biodegradable byproducts. Ozonation changes the functional groups in azo dye, resulting in more biologically degradable byproducts that are simply eliminated through biological treatment. Activated sludge treatment as well as the coagulation-flocculation technique with 80% waste water removal efficiency. Sequencing batch reactor is a fill-and- draw activated sludge-based system for wastewater treatment and has been proposed as an alternative technique for treating industrial effluents. We briefed a promising novel technology for textile effluent de-colorisation in this chapter.