Novel silver/poly-1-vinyl-1,2,4-triazole nanocomposite materials—possessing antimicrobial activity against Gram-positive and Gram-negative bacteria—have been synthesized and characterized in the solid state and aqueous solution by complex of modern physical-chemical and biologic methods. TEM-monitoring has revealed the main stages of microbial cell (E. coli) destruction by novel nanocomposite. The concept of direct polarized destruction of microbes by nanosilver proposed by the authors allows the relationship between physicochemical and antimicrobial properties of novel nanocomposites. At the same time, it was shown that the nanocomposite was nontoxic to the fibroblast cell culture. Thus, the synthesized nanocomposite combining antibacterial activity against Gram-positive and Gram-negative bacteria as well as the absence of toxic effects on mammalian cells is a promising material for the development of catheters, coatings for medical devices.

Nanocomposite of heteropolysaccharide arabinogalactan and elemental selenium (0.54% of Se) has been prepared and studied by means of transmission electron microscopy, UV spectroscopy, and X-ray...

The effect an original nanocomposite of elemental selenium and arabinogalactan heteropolysaccharide has on the rate of the calcification of calluses in the case of a traumatic injury is studied experimentally using confocal and fluorescence microscopy. With a local increase in the selenium concentration in the area of the traumatic injury, we observe low intensity of mineralization for the forming callus and a slowing down of bone regeneration. The difficulties of visualizing fluorescent labels introduced simultaneously are discussed.

The relationship between the structures of sulfated arabinogalactan argentic nanocomposites with silver contents of 5.3 to 9.2% is studied along with their antimicrobial activities. It is found that...