Mohamad Sawan

Prof. Mohamad Sawan

Westlake University, Hangzhou, Zhejiang, China
orcid

Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 June 2020 in Micromachines
Verified
Journal Article
Open access
PDF file
NANeda Azizipour
Neda Azizipour
RARahi Avazpour
Rahi Avazpour
Derek RosenzweigDerek Rosenzweig
Derek Rosenzweig
Mohamad SawanMohamad Sawan
Mohamad Sawan
AAAbdellah Ajji
Abdellah Ajji
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel biomedical application for microfluidic based devices has emerged in recent years and microengineered cell culture platforms have been created. These micro-devices, known as organ-on-a-chip (OOC) platforms mimic the in vivo like microenvironment of living organs and offer more physiologically relevant in vitro models of human organs. Consequently, the concept of OOC has gained great attention from researchers in the field worldwide to offer powerful tools for biomedical researches including disease modeling, drug development, etc. This review highlights the background of biochip development. Herein, we focus on applications of LOC devices as a versatile tool for POC applications. We also review current progress in OOC platforms towards body-on-a-chip, and we provide concluding remarks and future perspectives for OOC platforms for POC applications.

31 May 2021 in Sensors
Verified
Journal Article
Open access
PDF file
Guoguang RongGuoguang Rong
Guoguang Rong
YZYuqiao Zheng
Yuqiao Zheng
Mohamad SawanMohamad Sawan
Mohamad Sawan
Wearable sensors have gained popularity over the years since they offer constant and real-time physiological information about the human body. Wearable sensors have been applied in a variety of ways in clinical settings to monitor health conditions. These technologies require energy sources to carry out their projected functionalities. In this paper, we review the main energy sources used to power wearable sensors. These energy sources include batteries, solar cells, biofuel cells, supercapacitors, thermoelectric generators, piezoelectric and triboelectric generators, and radio frequency (RF) energy harvesters. Additionally, we discuss wireless power transfer and some hybrids of the above technologies. The advantages and drawbacks of each technology are considered along with the system components and attributes that make these devices function effectively. The objective of this review is to inform researchers about the latest developments in this field and present future research opportunities.

31 May 2018 in IEEE Transactions on Very Large Scale Integration (VLSI) Systems
Verified
Journal Article
Closed access
Ahmad HassanAhmad Hassan
Ahmad Hassan
YSYvon Savaria
Yvon Savaria
Mohamad SawanMohamad Sawan
Mohamad Sawan
Several industrial applications require specific electronic systems installed in harsh environments to perform measurements, monitoring, and control tasks such as in space exploration, aerospace missions, automotive industries, down-hole oil and gas industry, and geothermal power plants. The extreme environment could be surrounding high-, low-, and wide-range temperature, intense radiation, or even a combination of above conditions. We review, in this paper, the main leading applications that demand advanced technologies to fit the unconventional requirements of extreme operating conditions, discussing their main merits and limits compared to established and emerging technologies in this field, including silicon (Si), silicon on insulator (SOI), silicon germanium (SiGe), silicon carbide (SiC) as well as III-V semiconductors particularly the gallium nitride (GaN) semiconductor. In spite of successfully exceeding extreme conditions borders by developing advanced semiconductor devices dedicated for harsh environments, especially in high-temperature applications, the packaging challenges are still limiting the reliability of the developed technologies. Those challenges are examined in this review in terms of limitations and proposed solutions.

12 April 2021 in IEEE Sensors Journal
Verified
Journal Article
Closed access
Mohamed AliMohamed Ali
Mohamed Ali
AEAli Elsayed
Ali Elsayed
AMArnaldo Mendez
Arnaldo Mendez
YSYvon Savaria
Yvon Savaria
Mohamad SawanMohamad Sawan
Mohamad Sawan
Breathing rate monitoring is a must for hospitalized patients with the current coronavirus disease 2019 (COVID-19). We review in this paper recent implementations of breathing monitoring techniques, where both contact and remote approaches are presented. It is known that with non-contact monitoring, the patient is not tied to an instrument, which improves patients’ comfort and enhances the accuracy of extracted breathing activity, since the distress generated by a contact device is avoided. Remote breathing monitoring allows screening people infected with COVID-19 by detecting abnormal respiratory patterns. However, non-contact methods show some disadvantages such as the higher set-up complexity compared to contact ones. On the other hand, many reported contact methods are mainly implemented using discrete components. While, numerous integrated solutions have been reported for non-contact techniques, such as continuous wave (CW) Doppler radar and ultrawideband (UWB) pulsed radar. These radar chips are discussed and their measured performances are summarized and compared.

1 February 2021 in Journal of Pharmaceutical Analysis
Verified
Journal Article
Open access
SBSumin Bian
Sumin Bian
BZBowen Zhu
Bowen Zhu
GRGuoguang Rong
Guoguang Rong
Mohamad SawanMohamad Sawan
Mohamad Sawan
Continuous drug monitoring is a promising alternative to current therapeutic drug monitoring strategies and has strong potential to reshape our understanding of pharmacokinetic variability and to improve individualised therapy. This review highlights recent advances in biosensing technologies that support continuous drug monitoring in real time. We focus primarily on aptamer-based biosensors, wearable and implantable devices. Emphasis is given to the approaches employed in constructing biosensors. We pay attention to sensors’ biocompatibility, calibration performance, long-term characteristics stability and measurement quality. In the end, we discuss about the current challenges and issues to address in continuous drug monitoring to make it a promising, future tool for individualised therapy. The ongoing efforts are expected to result in fully integrated implantable drug biosensing technology. Thus, we may anticipate an era of advanced healthcare in which wearable and implantable biochips automatically adjust drug dosing in response to patient health conditions enabling the management of diseases and enhancing individualised therapy.

2 August 2021 in IEEE Transactions on Circuits and Systems I: Regular Papers
Verified
Journal Article
Closed access
SNSeyed Mohammad Noghabaei
Seyed Mohammad Noghabaei
RRRafael L. Radin
Rafael L. Radin
YSYvon Savaria
Yvon Savaria
Mohamad SawanMohamad Sawan
Mohamad Sawan
Radio frequency energy harvesting (RFEH) is very attractive for the Internet of things (IoT) and self-powered micro-systems such as wearable biomedical devices and wireless sensor networks. This paper proposes, analyzes, and implements a new RF-DC converter in standard 130 nm CMOS technology. The developed converter is designed and optimized for ultra-low-power IoT and wearable biomedical applications using the 900 MHz ISM band. The proposed 10-stage cross-connected rectifier compensates the transistors threshold voltage by using both dynamic and static bias compensation techniques. An analytical model of the rectifier based on the MOSFET transistor equations is presented, allowing optimization of the rectifier as a function of the number of stages and transistors sizing, improving the sensitivity and the input power range of the converter. The measurement results demonstrate a sensitivity of −25.5 dBm for 1 V output across a 5- $\text{M}\Omega $ resistive load and −29 dBm for a 100 $\text{M}\Omega $ load, which is better than the best previously reported results. The measured peak end-to-end efficiency of the proposed harvester is 42.4% at −16 dBm input power, delivering 2.19 V to a 450 $\text{k}\Omega $ load.