In recent years, scientific advancements have constantly increased at a significant rate in the field of biomedical science. Keeping this in view, the application of porphyrins and metalloporphyrins in the field of biomedical science is gaining substantial importance. Porphyrins are the most widely studied tetrapyrrole-based compounds because of their important roles in vital biological processes. The cavity of porphyrins containing four pyrrolic nitrogens is well suited for the binding majority of metal ions to form metalloporphyrins. Porphyrins and metalloporphyrins possess peculiar photochemical, photophysical, and photoredox properties which are tunable through structural modifications. Their beneficial photophysical properties, such as the long wavelength of emission and absorption, high singlet oxygen quantum yield, and low in vivo toxicity, have drawn scientists’ interest to discover new dimensions in the biomedical field. Applications of porphyrins and metalloporphyrins have been pursued in the perspective of contrast agents for magnetic resonance imaging (MRI), photodynamic therapy (PDT) of cancer, bio-imaging, and other biomedical applications. This review discusses photophysics and the photochemistry of porphyrins and their metal complexes. Secondly, it explains the current developments and mode of action for contrast agents for MRI. Moreover, the application of porphyrin and metalloporphyrin-based molecules as a photosensitizer in PDT of cancer, the mechanism of the generation of reactive oxygen species (ROS), factors that determine the efficiency of PDT, and the developments to improve this technology are delineated. The last part explores the most recent research and developments on metalloporphyrin-based materials in bio-imaging, drug delivery, and the determination of ferrochelatase in bone marrow indicating their prospective clinical applications.

On the basis of first principle density functional theory, we have studied the stability, electronic structure, and hydrogen storage capacity of a monolayer calcium doped graphane (CHCa). The stability of CHCa was further investigated using the ab initio molecular dynamics study. The binding energy of Ca on graphane sheet was found to be higher than its bulk cohesive energy, which indicates the stability of CHCa. It was observed that with a doping concentration of 11.11% of Ca on graphane sheet, a reasonably good H₂ storage capacity of 6 wt. % could be attained. The adsorption energies of H₂ were found to be 0.1 eV, within the range of practical H₂ storage applications.

In many industrial products stretching surfaces and magnetohydrodynamics are being used. The purpose of this article is to analyze magnetohydrodynamics (MHD) non-Newtonian Maxwell fluid with nanomaterials in a surface which is stretching exponentially. Thermophoretic and Brownian motion effects are incorporated using Buongiorno model. The given partial differential system is converted into nonlinear ordinary differential system by employing adequate self-similarity transformations. Locally series solutions are computed using BVPh 2.0 for wide range of governing parameters. It is observed that the flow is expedite for higher Deborah and Hartman numbers. The impact of thermophoresis parameter on the temperature profile is minimal. Mathematically, this study describes the reliability of BVPh 2.0 and physically we may conclude the study of stretching surfaces for non-Newtonian Maxwell fluid in the presence of nanoparticles can be used to obtain desired qualities.