Ana (R) Miljkovic

Dr. Ana (R) Miljkovic

University of Novi Sad, Novi Sad, Serbia
orcid
Primarius, PhD-Asist., Specialist in general medicine,Depart...

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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31 March 2022 in Plants
Verified
Journal Article
Open access
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Milica AćimovićMilica Aćimović
Milica Aćimović
Olja ŠovljanskiOlja Šovljanski
Olja Šovljanski
Vanja TravičićVanja Travičić
Vanja Travičić
LPLato Pezo
Lato Pezo
Valtcho ZheljazkovValtcho Zheljazkov
Valtcho Zheljazkov
Ljubodrag VujisićLjubodrag Vujisić
Ljubodrag Vujisić
Steam distillation was used for the isolation of Dracocephalum moldavica L. (Moldavian dragonhead) essential oil (DMEO). This aromatic herbaceous plant is widespread across the Northern Hemisphere regions and has been utilized in health-improving studies and applications. In addition to the DMEO, the hydrolate (DMH), a byproduct of the distillation process, was also collected. The DMEO and DMH were analyzed and compared in terms of their chemical composition, as well as their in vitro biological activities. The main component in DMEO was geranyl acetate, while geranial was dominant in DMH. The DMEO demonstrated better antioxidant and antimicrobial activities compared with the DMH against Staphylococcus aureus, Escherichia coli, Salmonella Typhimurium, and Listeria monocytogenes, which represent sources of food-borne illness at the global level. The DMEO and DMH show promise as antioxidant and antimicrobial additives to various products.

29 June 2022 in Agronomy
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Journal Article
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Milica AćimovićMilica Aćimović
Milica Aćimović
MRMilica Rat
Milica Rat
LPLato Pezo
Lato Pezo
Biljana LončarBiljana Lončar
Biljana Lončar
MPMilada Pezo
Milada Pezo
JLJovan Lazarević
Jovan Lazarević
Garden angelica (Angelica archangelica L.), native to the northern temperate region, is widespread in Europe and Asia. Since the middle ages, it has been used for healing and as a vegetable in traditional dishes. In the modern era, it has been proven that A. archangelica has a complex chemical composition. The main derivatives that contribute to the plant’s biological activities are essential oil and coumarins. In this review, the focus is on the cross-analysis of the taxonomy of A. archangelica, and its distribution in different regions, with the presentation of the richness of its biochemical composition, which overall contributes to the widespread use of the roots of this plant in folk medicine. It belongs to the plants that were introduced to the wider area of Central, Eastern, and Southern Europe; as a medicinal plant, it represents a significant part of the medical flora of many areas. Cluster analysis of pooled data indicates a clear differentiation of chemotypes.

1 August 2024 in Antibiotics
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Journal Article
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Olja ŠovljanskiOlja Šovljanski
Olja Šovljanski
Milica AćimovićMilica Aćimović
Milica Aćimović
AVAna Tomić (ex. Vidaković)
Ana Tomić (ex. Vidaković)
Biljana LončarBiljana Lončar
Biljana Lončar
Ana (R) MiljkovicAna (R) Miljkovic
Ana (R) Miljkovic
LPLato Pezo
Lato Pezo
Helichrysum italicum (Roth) G. Don is a typical Mediterranean plant, with limited distribution on the islands of Sardinia, Corsica, and the Iberian Peninsula, as well as the islands of the Adriatic Sea and the Balkan Peninsula. In these regions, H. italicum is mainly collected from spontaneous nature, while in recent years, there has been a pronounced cultivation trend due to increased demand and market requirements for constant quality of raw materials. Bearing in mind that biological activity is linked with chemical composition, this review aimed to collect data from different scientific databases (Scopus, PubMed, Web of Science, and Google Scholar) on the antimicrobial activity of essential oil and its chemical composition. A total of 20 papers investigating the antibacterial, antibiofilm, and antifungal activities of H. italicum essential oil were found. Furthermore, in these samples, several compounds occurred as dominant: neryl acetate, α-pinene, and γ-curcumene. These compounds are known for their antimicrobial properties, which likely contribute to the essential oil’s efficacy against various microbial strains.

7 June 2023 in Molecules
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Milica AćimovićMilica Aćimović
Milica Aćimović
JJJovana Stanković Jeremić
Jovana Stanković Jeremić
Ana (R) MiljkovicAna (R) Miljkovic
Ana (R) Miljkovic
MRMilica Rat
Milica Rat
Biljana LončarBiljana Lončar
Biljana Lončar
Ironwort (Sideritis montana L.), mountain germander (Teucrium montanum L.), wall germander (Teucrium chamaedrys L.), and horehound (Marrubium peregrinum L.) are species widely distributed across Europe and are also found in North Africa and West Asia. Because of their wide distribution they express significant chemical diversity. For generations, these plants have been used as medical herbs for treating different aliments. The aim of this paper is to analyze volatile compounds of four selected species that belong to the subfamily Lamioideae, family Lamiaceae, and inspect scientifically proven biological activities and potential uses in modern phytotherapy in relation to traditional medicine. Therefore, in this research, we analyze the volatile compounds from this plants, obtained in laboratory by a Clevenger-type apparatus, followed by liquid–liquid extraction with hexane as the solvent. The identification of volatile compounds is conducted by GC-FID and GC-MS. Although these plants are poor in essential oil, the most abundant class of volatile components are mainly sesquiterpenes: germacrene D (22.6%) in ironwort, 7-epi-trans-sesquisabinene hydrate (15.8%) in mountain germander, germacrene D (31.8%) and trans-caryophyllene (19.7%) in wall germander, and trans-caryophyllene (32.4%) and trans-thujone (25.1%) in horehound. Furthermore, many studies show that, in addition to the essential oil, these plants contain phenols, flavonoids, diterpenes and diterpenoids, iridoids and their glycosides, coumarins, terpenes, and sterols, among other active compounds, which affect biological activities. The other goal of this study is to review the literature that describes the traditional use of these plants in folk medicine in regions where they grow spontaneously and compare them with scientifically confirmed activities. Therefore, a bibliographic search is conducted on Science Direct, PubMed, and Google Scholar to gather information related to the topic and recommend potential applications in modern phytotherapy. In conclusion, we can say that selected plants could be used as natural agents for promoting health, as a source of raw material in the food industry, and as supplements, as well as in the pharmaceutical industry for developing plant-based remedies for prevention and treatment of many diseases, especially cancer.

20 March 2024 in Journal of Agronomy, Technology and Engineering Management (JATEM)
Verified
Journal Article
Closed access
Ana (R) MiljkovicAna (R) Miljkovic
Ana (R) Miljkovic
Milica AćimovićMilica Aćimović
Milica Aćimović
BTBiljana Božanić Tanjga
Biljana Božanić Tanjga
Biljana LončarBiljana Lončar
Biljana Lončar
VRVidak Raicevic
Vidak Raicevic
LPLato Pezo
Lato Pezo
The purpose of this systematic overview is to establish the impact of inhalation and topical application of Rosa damascena essential oil in aromatherapy practice. A bibliometric analysis using the different scientific databases was conducted to examine scientific documents related to “rose aromatherapy” and “Rosa damascena aromatherapy”. Microsoft Excel and VOSviewer software were used to extract and visualize information. Founded on a review of 93 papers, the scent of rose essential oil has applications in aromatherapy for reducing anxiety, alleviating pain, improving sleep quality, as well as alleviating physiological symptoms during menopause and PMS. It aids in mitigating stress and reducing stress and reducing depression and fatigue, for relaxation and improving cognitive function, among other benefits. Ultimately, rose essential oil is safe and suitable for self-administration via inhalation or topical application, either alone or with other essential oils.

9 November 2023 in Pathogens
Verified
Journal Article
Open access
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Olja ŠovljanskiOlja Šovljanski
Olja Šovljanski
ARAleksandra Ranitović
Aleksandra Ranitović
AVAna Tomić (ex. Vidaković)
Ana Tomić (ex. Vidaković)
NĆNenad Ćetković
Nenad Ćetković
Ana (R) MiljkovicAna (R) Miljkovic
Ana (R) Miljkovic
DCDragoljub Cvetković
Dragoljub Cvetković
The food industry has recognized a pressing need for highly effective disinfection protocols to decrease the risk of pathogen emergence and proliferation in food products. The integration of antimicrobial treatments in food production has occurred as a potential strategy to attain food items of superior quality with respect to microbiological safety and sensory attributes. This study aims to investigate the individual and synergistic effects of heat and peroxyacetic acid on the inactivation of bacterial cells, considering various contact times and environmental conditions. Four Salmonella serotypes, isolated from industrial meat production surfaces, were employed as model organisms. By systematically assessing the impacts of individual factors and synergistic outcomes, the effectiveness of bacterial cell inactivation and the efficiency of heat and peroxyacetic acid could be predicted. To better approximate real-world food processing conditions, this study also incorporated a bovine albumin-rich condition as a simulation of the presence of organic loads in processing steps. The findings revealed the essential need for a synergistic interplay of investigated parameters with the following optimized values: 1.5% concentration of peroxyacetic acid, temperature range of 60–65 °C, and contact time of 3 min for the complete effect regardless of the degree of contamination.