Bruxism-related orofacial pain is a common clinical manifestation associated with muscular hyperactivity, psychoemotional factors, and altered pain sensitivity. Immersive virtual reality (iVR) has emerged as a non-pharmacological strategy for pain management; however, evidence in individuals with bruxism-related pain remains limited. This pilot study evaluated the feasibility, tolerability, and preliminary clinical responses associated with an iVR intervention in adults with bruxism-related orofacial pain. A longitudinal pilot study with repeated assessments (T0–T4) was conducted in 15 adults with self-reported bruxism-related orofacial pain. Participants completed two standardized relaxation-oriented iVR sessions using an Oculus Quest 3 head-mounted display. Feasibility, immersive experience, cybersickness symptoms, pain intensity, and pressure pain threshold (PPT) were evaluated. All participants completed the intervention protocol and follow-up assessments, resulting in 100% adherence. Cybersickness symptoms were mild, and immersive experience scores indicated high perceived presence. Pain intensity decreased progressively throughout follow-up, with the greatest reduction observed at T4. The pressure pain threshold demonstrated modest temporal increases, particularly in the splenius, upper trapezius, and temporalis regions. The intervention was feasible and well tolerated and was accompanied by exploratory reductions in pain-related outcomes over time. These findings support future controlled studies to clarify the clinical effects of immersive virtual reality in individuals with bruxism-related orofacial pain.

Background and Objectives: Comprehensive physical profiling is important for monitoring athletic development in youth soccer players (YSP), yet integrated data from competitive South American players remain limited. This study aimed to characterize the anthropometric profile, neuromuscular performance, and cardiorespiratory fitness of competitive Chilean YSP and explore associations among these components. Methods: This cross-sectional study included 24 male YSP from a Chilean professional club academy. Participants underwent anthropometric assessment, bilateral quadriceps isometric strength testing, vertical jump testing (Squat Jump [SJ], Countermovement Jump [CMJ], and Abalakov Jump [ABK]), and maximal cardiopulmonary exercise testing. The primary analysis was an integrated characterization of anthropometric, neuromuscular performance, and cardiorespiratory fitness. Secondary exploratory analyses included correlations with false discovery rate adjustment and multiple linear regression. Results: Participants had a median age of 13.5 years (IQR: 13.0–14.0) and a BMI of 21.1 ± 1.6 kg·m⁻². Mean bilateral quadriceps strength was 406.1 ± 70.0 N, while mean jump heights were 24.6 ± 4.2 cm for SJ, 28.4 ± 3.7 cm for CMJ, and 33.4 ± 5.3 cm for ABK. The average relative VO₂peak was 55.0 ± 4.7 mL·kg⁻¹·min⁻¹, while absolute VO₂peak was slightly higher than predicted. Bilateral quadriceps strength was positively associated with all three jumps before FDR adjustment; after FDR correction, the associations with CMJ and ABK remained statistically significant, whereas the association with SJ did not. Relative VO₂peak was not associated with CMJ performance. Conclusions: This study provides an integrated characterization of physical performance within this cohort of youth soccer players. Quadriceps strength was associated with vertical jump performance, whereas relative VO₂peak was not associated with CMJ, supporting assessment of neuromuscular and cardiorespiratory capacities.